Hero or Villain?—Sir Richard Doll and Occupational Cancer

Abstract

In 2006, the English media broke the story that Sir Richard Doll had for many years been retained on a, secret consultancy by Monsanto. Doll's colleagues rushed to his defense, arguing that the story was an unjustified smear on a great man whose work had saved millions of lives. However, Doll's conflicts of interest in his occupational health epidemiology are shown to sit uneasily alongside his more independent smoking/lung cancer studies.     

Distinctiveness of APCS Programs: Commentary

[Clin Psychol Sci Prac 18: 21–23, 2011] This brief article comments on “The Heterogeneity of Clinical Psychology Ph.D. Programs and the Distinctiveness of APCS Programs” (Sayette, Norcross, & Dimoff, 2011). I wish to make three points: First, what point was there in selecting “specialized institutions” as a comparative category? Second, without doubt it is very desirable to have gifted students and be able to support them. The fact that such students populate Academy of Psychological Clinical Science (APCS) programs represents favorable national public policy decisions regarding research universities. The broader underlying question regarding both programs and students is “how good is good enough” regarding grades and GREs in light of the range of viable roles for psychologists in the country? Third, the espoused epistemology of APCS should be less narrow.     

Richard钉治疗股骨转子间骨折

2002～2006年，我科应用Richard钉治疗股骨转子间骨折患者41例，取得满意疗效。     

Smooth muscle cells of human veins show an increased response to injury at valve sites

Objective

Venous valves are essential but are prone to injury, thrombosis, and fibrosis. We compared the behavior and gene expression of smooth muscle cells (SMCs) in the valve sinus vs nonvalve sites to elucidate biologic differences associated with vein valves.

Pain measurement: an overview

The practice and theoretical basis of pain measurement is reviewed and critically examined in the areas of animal research, human subjects laboratory investigation and clinical study. The advantages and limitations of both physiological and behavioral methods are discussed in each area, and subjective report procedures are evaluated in human laboratory and clinical areas. The need for procedures that bridge these areas is emphasized and specific issues are identified. Progress in the technology of pain measurement over recent decades is reviewed and directions for future work are suggested.     

Computed Tomography Measures of Nutrition in Patients With End-Stage Liver Disease Provide a Novel Approach to Characterize Deficits

Background

Patients with cirrhosis and end-stage liver disease (ESLD) develop severe nutrition deficits that affect morbidity and mortality. Laboratory measures of nutrition fail to fully assess clinical deficits in muscle mass and fat stores. This study employs computed tomography imaging to assess muscle mass and subcutaneous and visceral fat stores in patients with ESLD.

Has the Expansion in Extended Criteria Deceased Donors Led to a Different Type of Delayed Graft Function and Poorer Outcomes?

Objectives

There has been considerable change in the practice of deceased kidney transplantation in the past 15 years, with more extreme phenotypes implanted. The aim of this study was to determine whether increased use of expanded criteria donors (extended criteria donors and donors after circulatory death) affected clinical outcomes, including the incidence and pattern of delayed graft function.