Database analysis of hypersensitivity pneumonitis in Japan

BackgroundThree epidemiological small-scale studies on hypersensitivity pneumonitis (HP) have been performed in Japan to date. Herein, we aimed to clarify the clinical characteristics of various types of HP diseases using a large nationwide database in Japan.MethodsWe used the Japanese Diagnostic Procedure Combination database that includes data from 1,031 participant hospitals. Patients with HP from 2011 to 2017 were identified using International Classification of Diseases 10th Revision codes. We analyzed patient characteristics, the yearly transition of the number of HP cases, rate per one million hospitalizations, geographical distribution, seasonality, and risk factors for in-hospital mortality.ResultsIn total, 3,634 patients with HP were identified, including summer-type HP (SHP) (n = 490), bird fancier's lung (BFL) (n = 199), ventilation pneumonitis (n = 106), farmer's lung (n = 48), and unspecified HP (n = 2761). The length of hospital stay was significantly longer in patients with BFL (19 days) than in patients with SHP (15 days). SHP was more prevalent in the southwestern region of Japan, and hospitalization occurred mainly in summer (37.8%) and fall (37.3%). Ventilation pneumonitis was predominant in winter (28.6%) and spring (38.7%). In-hospital mortality was significantly associated with old age (p < 0.001), low body mass index (p = 0.016), severe dyspnea (p < 0.001), and BFL diagnosis on admission (p = 0.031).ConclusionsThis study revealed the clinical characteristics of SHP and BFL, including the frequency of causative antigens, geographical distribution, seasonality, and risk factors for mortality, which may help in diagnosing HP and identifying causative antigens.     

超声三维斑点追踪技术评估左室型单心室Glenn术后心功能变化

目的 应用超声三维斑点追踪技术(three-dimensional speckle tracking imaging,3DSTI)观察左室型单心室患儿Glenn手术前、后左心功能的变化.方法 对17例左室型单心室患儿于Glenn术前及术后分别进行三维超声和心脏磁共振检查,估测左心功能;术前、术后分别与年龄、性别匹配的1...     

日间手术模式下吻合器痔上黏膜环切术与外剥内扎术治疗混合痔的临床疗效对比

目的 比较日间手术模式下吻合器痔上黏膜环切术（PPH）与外剥内扎术（MMH）治疗混合痔的临床疗效。方法 回顾性收集2019年10月至2021年5月在新疆医科大学第一附属医院日间手术治疗病房接受手术治疗的161例混合痔病人的临床资料。按手术方式的不同分为两组：P组病人接受PPH，共96例，M组接受MMH，共65例。比较两组病人住院时间、住院总费用、手术切口视觉模拟法（VAS）疼痛评分、术后延迟出院率、非计划再入院率、术后复发率以及临床疗效等资料。术后随访6个月。结果 P组与M组在治愈率（94.79%比96.92%）、延迟出院率（10.42%比12.31%）、住院时间以及术后复发率等方面比较均差异无统计学意义（P>0.05）。M组非计划再入院率（0.00%比7.29%）、住院总费用低于P组，均差异有统计学意义（P<0.05）。P组术后1、3、5、7 d的VAS疼痛评分均小于M组，均差异有统计学意义（P<0.05）。结论 日间手术模式下MMH与PPH有同样的临床疗效，同时MMH住院总费用更低且更为安全。PPH虽然有着较小的术后疼痛，但是术后非计划再入院率较高，故目前在日间模...