全文获取类型
收费全文 | 34862篇 |
免费 | 2232篇 |
国内免费 | 642篇 |
专业分类
耳鼻咽喉 | 324篇 |
儿科学 | 604篇 |
妇产科学 | 221篇 |
基础医学 | 1730篇 |
口腔科学 | 402篇 |
临床医学 | 6746篇 |
内科学 | 2602篇 |
皮肤病学 | 57篇 |
神经病学 | 2928篇 |
特种医学 | 12239篇 |
外科学 | 3095篇 |
综合类 | 3657篇 |
预防医学 | 609篇 |
眼科学 | 198篇 |
药学 | 998篇 |
10篇 | |
中国医学 | 188篇 |
肿瘤学 | 1128篇 |
出版年
2024年 | 20篇 |
2023年 | 314篇 |
2022年 | 973篇 |
2021年 | 1312篇 |
2020年 | 1083篇 |
2019年 | 827篇 |
2018年 | 1169篇 |
2017年 | 1337篇 |
2016年 | 1549篇 |
2015年 | 1295篇 |
2014年 | 2479篇 |
2013年 | 2010篇 |
2012年 | 2142篇 |
2011年 | 2340篇 |
2010年 | 2018篇 |
2009年 | 2051篇 |
2008年 | 2047篇 |
2007年 | 1902篇 |
2006年 | 1643篇 |
2005年 | 1523篇 |
2004年 | 1269篇 |
2003年 | 872篇 |
2002年 | 539篇 |
2001年 | 693篇 |
2000年 | 675篇 |
1999年 | 507篇 |
1998年 | 495篇 |
1997年 | 468篇 |
1996年 | 414篇 |
1995年 | 390篇 |
1994年 | 263篇 |
1993年 | 235篇 |
1992年 | 243篇 |
1991年 | 174篇 |
1990年 | 127篇 |
1989年 | 84篇 |
1988年 | 80篇 |
1987年 | 61篇 |
1986年 | 40篇 |
1985年 | 25篇 |
1984年 | 6篇 |
1983年 | 10篇 |
1982年 | 4篇 |
1981年 | 5篇 |
1980年 | 3篇 |
1978年 | 4篇 |
1977年 | 2篇 |
1976年 | 5篇 |
1975年 | 4篇 |
1972年 | 2篇 |
排序方式: 共有10000条查询结果,搜索用时 468 毫秒
81.
MRI在心脏瓣膜病中的诊断价值 总被引:1,自引:0,他引:1
目的 探讨多序列MR扫描在心脏瓣膜病中的诊断价值。方法 回顾性分析56例心脏瓣膜病患者的影像学资料,患者分别采用超声心动图(UCG)、二维(2D)黑血及亮血序列、K-空间节段真实稳态进动快速扫描序列(True FISP)对瓣膜病进行定性评价,15例患者还进行小角度快速激发(FLASH)电影序列和流速编码电影(VEC)定量分析,并将MR结果与UCG进行对比。结果 UCG和MRI诊断二尖瓣狭窄(MS)2例,二尖瓣关闭不全(MI)23例;主动脉瓣狭窄(AS)7例,其中二瓣畸形5例;主动脉瓣关闭不全(AI)13例;三尖瓣关闭不全(TI)2例;复合或联合瓣膜病9例。受累心腔的增大和升主动脉的扩张是其主要形态学改变,异常的血液湍流信号是受累瓣膜的直接征象。VEC-MR定量分析与多普勒超声一致性好:6例AS,MR和UCG检查结果相关性分析,相关系数和校正相关系数分别为:R=0,975、Rsq=0.951(P〈0.01),AI9例,分别为R=0.965、Rsq=0.932(P〈0.01)。结论 MR多序列综合扫描可对心脏瓣膜病特别是主动脉瓣疾病进行准确的定性及定量评价。 相似文献
82.
83.
Dr. E. Mietzsch M. Koch M. Schaldach J. Werner B. Bellenberg K. U. Wentz 《Medical & biological engineering & computing》1998,36(6):673-678
The application of spin-echo magnetic resonance imaging sequences on non-invasive temperature imaging for temperature mapping
of human limbs is investigated. In an in vitro expriment performed on a meat sample, the equilibrium magnetisation P and the
spin-lattice relaxation time T1 are calculated from the values for the repetition time TR and the signal intensities obtained by a spin-echo sequence at
different tissue temperatures tures as measured by a fibre-optic probe. T1 is linearly correlated to the tissue temperature, and P is linearly correlated to the reciprocal value of the absolute temperature.
Both effects, taken together, lead to a non-linear dependency of the signal intensity on temperature. Therefore a TR leading
to maximum temperature dependency of the signal intensity is calculated and used in the futher experiments. In the in vivo
experiments, the lower legs of two volunteers are cooled from outside. Images are acquired with a spin-echo sequence (1.5T,
TR=1200 ms, TE=10 ms). A rise in signal intensity in the muscle with falling skin temperature is observed, particularly in
more peripheral muscle layers. This study shows that spin-echo sequences can be used to monitor temperature changes and temperature
differences in living muscle tissue. 相似文献
84.
磁共振成像对颅内脑膜瘤水肿分析 总被引:1,自引:0,他引:1
目的:探讨脑膜瘤周围脑水肿的程度和肿瘤的生长部位.质地.组织学亚型的相关性.研究其瘤周水肿的形成原因.材料和方法:使用经手术和病理证实的65例脑膜瘤MRI和临床病理资料.观察分析脑膜瘤的瘤周水肿的程度.肿瘤的质地,组织学亚型等.结果:发生于大脑颅盖部或/和有矢状窦受累的脑膜瘤有明显的脑水肿.而发生于其它部位(颅底,丘脑、小脑、脑池等)无或只有轻度脑水肿.结论:轻度脑水肿主要是脑膜瘤对脑组织的直接压迫,而中,重度脑水肿主要是脑膜瘤对大脑表面引流静脉尤其是矢状窦的压迫或阻塞.脑水肿和肿瘤的发生部位有关,面和肿瘤的质地、组织学亚型无关. 相似文献
85.
Gliomatosis cerebri with good prognosis 总被引:4,自引:0,他引:4
Seiji Kannuki Hideki Hondo Kunio Ii Takanori Hirose Keizo Matsumoto 《Brain tumor pathology》1997,14(1):53-57
A 52-year-old man was admitted to our clinic with severe headache and bilateral papilledema. Magnetic resonance (MR) images
on admission demonstrated diffuse swelling of the cerebral cortex without formation of a tumor mass. Biopsy revealed diffuse
infiltration with neoplastic glial cells. After radiation and chemotherapy, the MR images returned to normal. The morphological
and neurological features of the present case met the criteria for gliomatosis cerebri. However, this patient showed an unusually
good response to radiation and chemotherapy. 相似文献
86.
Juhani Trmnen Osmo Tervonen Antero Koivula Juhani Junila Ilkka Suramo 《Journal of magnetic resonance imaging : JMRI》1996,6(5):805-811
The purpose of this study was to explore systematically the effect of the imaging parameters changeable by the user in spin-echo (SE) imaging sequences to minimize image distortion when imaging joint prostheses. A titanium alloy hip joint prosthesis was studied at 1.0 T. The SE imaging parameters were bandwidth/pixel (BW/p), TE, strength of encoding gradients (matrix size), echo train length (ETL), and direction of phase and frequency encoding. The effect of ETL in rapid acquisition relaxation enhanced (RARE) sequences was also evaluated with a turbo-SE sequence using a different ETL with the same TR and an effective TE. It is concluded that an optimized image quality can be achieved in SE imaging by using a high bandwidth/pixel value (at least 130 Hz/pixel), a high resolution matrix (256–512), sequences with multiple refocusing, and a frequency-encoding axis parallel to the long axis of the prosthesis. The degree of distortion is reduced with this optimized technique. 相似文献
87.
Posterior cranial fossa dimensions in the Chiari I malformation: Relation to pathogenesis and clinical presentation 总被引:8,自引:0,他引:8
Summary Skull dimensions were measured on lateral skull radiographs in 33 adult patients with MRI-verified Chiari I malformations and in 40 controls. The posterior cranial fossa was significantly smaller and shallower in patients than in controls. In the patients, there was a positive correlation between posterior fossa size and the degree of the cerebellar ectopia, which might indicate that a posterior cranial fossa which was originally too small had been expanded by the herniation of hindbrain structures at an early stage. Pyramidal signs and cerebellar symptoms and signs, which may be due to compression of neural structures, were associated with a large degree of ectopia and a relatively large posterior cranial fossa. Syringomyelia and headache, which may be due to the valve action of the herniated cerebellar tissue, were not associated with a particularly large posterior fossa or herniation. No special clinical presentation was associated with a very small posterior cranial fossa, which may indicate that a small posterior cranial fossa per se has little or no clinical significance, although it may be the primary developmental anomaly. 相似文献
88.
A case of MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) which presented as migraine
complicated by stroke is reported. Strokes associated with migraine have often been reported, but the mechanism remains unclear
and may include a variety of pathologies. MELAS also presents with migrainous headache, vomiting, and stroke-like symptoms.
Magnetic resonance imaging demonstrates characteristic findings. MELAS should be considered in the differential diagnosis
of infarct-like lesions with migrainous headaches in young adults, especially if the symptoms fluctuate and are accompanied
by a homonymous hemianopia.
Received: 23 September 1996 Accepted: 19 February 1997 相似文献
89.
Lyme disease is a cause of illness involving multiple organ systems, including, in 10–15 % of cases, the nervous system.
Peripheral radiculoneuritis, cranial neuritis, encephalitis and myelitis are among the neurological manifestations found in
the second and third stages. We present the MRI findings in isolated oculomotor nerve involvement by Lyme disease and discuss
the differential diagnosis.
Received: 14 June 1995 Accepted: 16 January 1996 相似文献
90.
We correlated MRI features with histopathological findings in an HIV-positive patient with vacuolar myelopathy. On MRI symmetrical
nonenhancing high-signal areas in the posterior columns on T2-weighted images result from extensive vacuolation visible on
histological sections.
Received: 18 November 1997 Accepted: 23 March 1997 相似文献