消肿止痛纱治疗尺桡骨骨折所致前臂肿胀疼痛的临床研究

目的探讨消肿止痛纱外敷对早期尺桡骨骨折所致的肿胀、疼痛的治疗效果。方法将220例早期尺桡骨骨折患者随机分为两组,每组110例,治疗组患肢抬高制动,使用消肿止痛纱外敷,对照组患肢抬高制动,伤处冰袋冷敷。观察两组伤后第1天,第3天和第6天肿胀、疼痛的治疗效果,统计各项积分变化情况并加以分析。结果消肿止痛纱外敷治疗尺桡骨骨折所致的软组织肿胀、疼痛疗效明显优于对照组（P〈0.01）。结论消肿止痛纱在治疗尺桡骨骨折后软组织肿胀、疼痛方面,效果良好,在临床上应加以推广。     

中药熏洗结合功能锻炼治疗四肢骨折后期关节功能障碍的疗效观察

目的：评价中药熏洗结合功能锻炼治疗四肢骨折后期关节功能障碍的临床观察。方法通过回顾分析64例四肢骨折后期关节功能障碍经过中药熏洗结合功能锻炼治疗的临床资料。结果64例患者获得随访,优49例,占76.6%;良11例,占17.2%;可3例,占4.7%;差1例,占1.5%,优良率93.8%。结论中药熏洗结合功能锻炼治疗四肢骨折后期关节功能障碍是一种安全、有效的治疗方法。     

Prevalence of use and reported side effects of herbal medicine among adults in Saudi Arabia

ObjectiveDespite the availability of well characterized and scientifically proven medicines, many people prefer the use of the less known herbal therapies that have no-scientific or evidence-based values as their first line of treatment. While this represents a growing worldwide issue, it is commonly practiced in developing countries including Saudi Arabia. Hence, the aim of the present study is to assess the prevalence of herbal medicine use, the most reported side effects and influencing factors in Saudi Arabia.DesignA community based cross sectional survey study.SettingsParticipants were recruited by convenience sampling method from local malls and family recreation sites.Main outcome measuresPrevalence of herbal medicine use and the associated risks.ResultsOut of the 1300 surveyed individuals, 1226 respondents (94 %) used herbal medicines for therapeutic purposes with the majority of the respondents using them based on traditional beliefs 699 (57 %) or family recommendations 417 (34 %). Young respondents <35 year olds who live in urban cities, showed a significantly better knowledge about herbal medicines use and the associated risks than their counterparts (p < 0.001). Despite the high percentage of reported side effects (46 %), more than half of the respondents 702 (54 %) use herbal medicines as their first line of therapy. However, the most reported reasons for the use of herbal medicine are the belief that they are safer, more effective and cheaper to buy than the standard medicines.ConclusionThere is a high prevalence use of non-scientifically proven herbal medicine and a low level of knowledge about their risks amongst participants.     

Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis

ObjectiveTo evaluate the efficacy of Western herbal medicines in the treatment of irritable bowel syndrome (IBS).DesignA computer-based search of MEDLINE, EMBASE, CINAHL, AMED, GreenFILE, Health Source: Nursing/Academic Edition, and the Cochrane Library was conducted. A hand-search of the bibliographies of relevant papers and previous meta-analyses and reviews was also undertaken. Trials were included in the review if they were double-blind and placebo-controlled investigating the effects of Western herbal medicines on IBS-related symptoms or quality of life. There were no language restrictions. Eligibility assessment and data extraction were performed by two independent researchers. For herbal medicines where there was more than 1 trial of similar design, data were synthesised using relative risk of symptoms improving using the random effects model.ResultsThirty-three trials were identified that met all eligibility criteria. Seventeen of these evaluated peppermint essential oil, fifteen other Western herbal medicines, and one trial evaluated peppermint oil in one arm and aniseed essential oil in the other arm. Eighteen different herbal preparations were evaluated in these trials. Data suggests that a number of Western herbal medicines may provide relief of IBS symptoms. Meta-analyses suggest that peppermint essential oil is both efficacious and well-tolerated in the short-term management of IBS. Aloe vera and asafoetida also demonstrated efficacy in reducing global IBS symptoms in meta-analyses. The herbal formulas STW 5, STW 5-II and Carmint, along with Ferula assa-foetida, Pimpenella anisum oil, the combination of Curcumin and Foeniculum vulgare oil, and the blend of Schinopsis lorentzii, Aesculus hippocastanum, and peppermint essential oil also demonstrated efficacy in rigorously-designed clinical trials.ConclusionA number of Western herbal medicines show promise in the treatment of IBS. With the exception of peppermint essential oil, Aloe vera, and asafoetida, however, none of the positive trials have been replicated. This lack of replication limits the capacity to make definitive statements of efficacy for these herbal medicines.     

艾灸结合中药熏蒸干预对慢性腰肌劳损患者疼痛及腰背功能恢复的影响

目的探究艾灸结合中药熏蒸干预对慢性腰肌劳损患者疼痛及腰背功能恢复的影响.方法选取某院2016年7月至2018年5月诊治的慢性腰肌劳损患者90例,采用随机数表法分为两组,各45例.对照组给予功能康复锻炼干预,观察组在对照组基础上采用艾灸联合中药熏蒸,对比两组临床疗效、治疗前后疼痛评分及腰背功能恢复情况.结果观察组治疗总有效率91.11%,高于对照组的66.67%,差异有统计学意义(P<0.05);观察组治疗后视觉模拟评分法(VAS)评分低于对照组,背肌力高于对照组,腰肌耐力时间长于对照组,差异有统计学意义(P<0.05).结论艾灸结合中药熏蒸干预可有效改善慢性腰肌劳损患者的临床症状,降低其腰痛评分,利于促进腰背功能的恢复,改善预后.     

Toxic acute hepatitis and hepatic fibrosis after consumption of chaparral tablets

In this report we describe a young, previously healthy woman who developed severe acute hepatitis after consumption of chaparral tablets, a commonly used herbal product. In this case, the elimination-rechallenge event and the exclusion of other possible aetiologic factors strongly supported true causality between the herbal product and the liver damage. Primary liver biopsy showed severe toxic hepatitis consistent with previous reports of chaparral-induced liver damage. Later, 6 months after the liver function tests had normalized, permanent hepatic fibrosis could still be seen.     

The chronic hepatotoxicity assessment of the herbal formula Zishen Yutai pill

Zishen Yutai pill (ZYP) is an oriental herbal formula, while hepatotoxicity assessment of ZYP was rarely evaluated. Therefore, our aim is to re-evaluate its hepatotoxicity in both normal and carbon tetrachloride (CCl₄) induced chronic liver injury rats. In the normal model, two doses of ZYP (1.575 and 9.450 g kg⁻¹ d⁻¹; i.e. 1 × , 6 × clinical doses) were given orally to rats for 24 weeks. In the chronic liver injury model, 10% CCl₄ was administered to rats abdominally twice a week at a dose of 5 mL kg⁻¹ for 12 consecutive weeks. Administration time started from 4 weeks after the beginning of CCl₄ treatment. Toxicological parameters included mortality, body weight, food consumption, clinical signs, biochemical parameters, gross observation, organ weight, necropsy findings and histopathology were monitored. In the normal model, we found no any mortality or abnormality in clinical signs, relative liver weight, biochemical parameters and histopathology in ZYP treatment groups. In the chronic liver injury model, liver damage related parameter such as ALT was elevated at the high dose of ZYP treatment in contrast to the CCl₄-treated group (P < 0.01). In histopathological assessment, there were no significant difference between ZYP treatment groups and CCl₄-treated group. No observed adverse effect on livers were established for 9.450 g kg⁻¹ d⁻¹ ZYP in the normal rats and 9.450 g kg⁻¹ d⁻¹ ZYP in the injury rats.     

中药灌肠并针灸佐治小儿病毒性肠炎60例疗效观察

目的：观察中药灌肠并针灸对小儿病毒性肠炎的疗效。方法：临床上将110例病儿随机分为治疗组和对照组,对照组不用抗生素,纠正水电解质及酸碱平衡紊乱,并常规口服思密达12包-1包;治疗组：在对照组相同治疗的基础上加用中药30m l-50m l灌肠2次/d,针灸1次/d,观察患儿治疗后症状缓解情况。结果：治疗后,治疗组总有效率96.7%,对照组总有效率68.0%,疗效明显优于对照组,且减少了不良反应。结论：中药灌肠并针灸治疗小儿病毒性肠炎操作简单,使用方便,不良反应少的优点,可明显提高治愈率。