乌鸡调经丸对动物子宫和卵巢的影响

实验观察了乌鸡调经丸对动物子宫和卵巢的影响。结果发现乌鸡调经丸小鼠按１．０,２．０,４．０ｇ／ｋｇ ｉｇ给药。可使幼年和成年血虚症小鼠子宫、卵巢重量显著增加,生长卵泡数明显增多;大鼠按１．０,２．０ｇ／ｋｇ给药,可使大鼠在体子宫明显松弛,并显著对抗催产素对子宫的兴奋作用。     

Expression of the somatostatin subtype 2A receptor in the rabbit retina

In the retina, somatostatin influences neuronal activity likely by acting at one or more somatostatin subtype (sst) receptors. Somatostatin and somatostatin-binding sites are distributed predominantly to the inner retina. The present study has investigated the cellular expression of one of the sst receptors, the sst_2A receptor isoform, in the rabbit retina. These studies have used a new polyclonal antibody directed to the predicted C-terminus of mouse sst_2A(361–369) receptor. Antibody specificity was tested by preadsorption of the primary antibody with a peptide corresponding to sst_2A(361–369). sst_2A Receptor immunoreactivity was localized mainly to the plasma membrane of rod bipolar cells and to sparsely occurring, wide-field amacrine cells. Immunostaining in rod bipolar cells was strongest in the axon and axon terminals in lamina 5 of the inner plexiform layer (IPL) and was weakest in the cell body and dendrites. Double-labeling experiments using a monoclonal antibody against protein kinase C (PKC; α and β), a rod bipolar cell-selective marker, showed complete colocalization. In horizontal sections of retina, immunostained bipolar cell bodies had a dense distribution, which is in agreement with the reported distribution of rod bipolar cell bodies. Immunoreactive amacrine cell bodies were located at the border of the inner nuclear layer and the IPL, and thin varicose processes ramified mainly in laminae 2 and 4 of the IPL. These observations indicate that somatostatin influences visual information processing in the retina 1) by acting presynaptically on rod bipolar cell axon terminals and b) by influencing the activity of sparsely occurring amacrine cells. J. Comp. Neurol. 393:93–101, 1998. © 1998 Wiley-Liss, Inc.     

寰枢椎后路椎弓根钉棒内固定技术在幼儿上颈椎疾患中的应用

目的：探讨后路寰枢椎椎弓根钉棒内固定技术在1～5岁幼儿上颈椎疾患中的应用效果。方法：回顾性研究本团队2013年5月～2022年3月采用寰枢椎椎弓根钉棒内固定技术治疗的上颈椎疾患幼儿13例，男10例，女3例；年龄15～68个月，平均43.85±17.56个月；体重9～22.5kg，平均16.32±3.23kg。患儿的主要临床表现为颈部疼痛伴活动受限，其中2例患儿伴有四肢乏力，1例患儿颈部偏斜为主要表现；术前美国脊髓损伤协会（American Spinal Injury Association,ASIA）分级C级2例，D级1例，E级10例。术前常规行张口位正侧位以及动力位X线片、CT骨三维重建、椎动脉CT血管造影（CT angiography,CTA）、MRI平扫或增强检查。常规行床边枕颌带或颅骨牵引，麻醉下颅骨牵引，13例患儿皆可获得完全或大部分复位，遂行后路寰枢椎复位椎弓根钉棒内固定术，所有椎弓根螺钉直径为3.5mm；除外4例新鲜单纯Ⅱ型齿状突骨折伴寰枢椎脱位患儿，其他病例皆行自体髂骨植骨融合；对3例因颅颈交界畸形或寰枢椎发育异常无法行寰枢椎椎弓根钉棒内固定术患儿采用枕颈固定融合方式治...