全文获取类型
收费全文 | 8761篇 |
免费 | 637篇 |
国内免费 | 181篇 |
专业分类
耳鼻咽喉 | 38篇 |
儿科学 | 115篇 |
妇产科学 | 32篇 |
基础医学 | 754篇 |
口腔科学 | 805篇 |
临床医学 | 1043篇 |
内科学 | 806篇 |
皮肤病学 | 59篇 |
神经病学 | 27篇 |
特种医学 | 123篇 |
外科学 | 283篇 |
综合类 | 1263篇 |
现状与发展 | 1篇 |
预防医学 | 2575篇 |
眼科学 | 74篇 |
药学 | 1226篇 |
7篇 | |
中国医学 | 251篇 |
肿瘤学 | 97篇 |
出版年
2024年 | 15篇 |
2023年 | 99篇 |
2022年 | 196篇 |
2021年 | 462篇 |
2020年 | 294篇 |
2019年 | 280篇 |
2018年 | 212篇 |
2017年 | 224篇 |
2016年 | 434篇 |
2015年 | 494篇 |
2014年 | 680篇 |
2013年 | 781篇 |
2012年 | 684篇 |
2011年 | 734篇 |
2010年 | 529篇 |
2009年 | 415篇 |
2008年 | 348篇 |
2007年 | 417篇 |
2006年 | 310篇 |
2005年 | 279篇 |
2004年 | 259篇 |
2003年 | 204篇 |
2002年 | 145篇 |
2001年 | 152篇 |
2000年 | 123篇 |
1999年 | 97篇 |
1998年 | 79篇 |
1997年 | 76篇 |
1996年 | 64篇 |
1995年 | 56篇 |
1994年 | 63篇 |
1993年 | 71篇 |
1992年 | 51篇 |
1991年 | 35篇 |
1990年 | 41篇 |
1989年 | 22篇 |
1988年 | 20篇 |
1987年 | 25篇 |
1986年 | 6篇 |
1985年 | 10篇 |
1984年 | 12篇 |
1983年 | 9篇 |
1982年 | 9篇 |
1981年 | 9篇 |
1980年 | 7篇 |
1979年 | 12篇 |
1978年 | 8篇 |
1977年 | 8篇 |
1976年 | 10篇 |
1974年 | 4篇 |
排序方式: 共有9579条查询结果,搜索用时 15 毫秒
991.
Chase-Topping ME Rosser T Allison LJ Courcier E Evans J McKendrick IJ Pearce MC Handel I Caprioli A Karch H Hanson MF Pollock KG Locking ME Woolhouse ME Matthews L Low JC Gally DL 《Emerging infectious diseases》2012,18(3):439-448
Escherichia coli O26 and O157 have similar overall prevalences in cattle in Scotland, but in humans, Shiga toxin-producing E. coli O26 infections are fewer and clinically less severe than E. coli O157 infections. To investigate this discrepancy, we genotyped E. coli O26 isolates from cattle and humans in Scotland and continental Europe. The genetic background of some strains from Scotland was closely related to that of strains causing severe infections in Europe. Nonmetric multidimensional scaling found an association between hemolytic uremic syndrome (HUS) and multilocus sequence type 21 strains and confirmed the role of stx(2) in severe human disease. Although the prevalences of E. coli O26 and O157 on cattle farms in Scotland are equivalent, prevalence of more virulent strains is low, reducing human infection risk. However, new data on E. coli O26-associated HUS in humans highlight the need for surveillance of non-O157 enterohemorrhagic E. coli and for understanding stx(2) phage acquisition. 相似文献
992.
Guillot S Descours G Gillet Y Etienne J Floret D Guiso N 《Emerging infectious diseases》2012,18(6):966-968
A macrolide antimicrobial drug was administered to a newborn with cough. On day 23 of hospitalization, macrolide-resistant Bordetella pertussis was isolated from nasopharyngeal aspirates. DNA sequencing and PCR-restriction fragment length polymorphism showed a 2047 A-to-G mutation in the 3 copies of the 23S rRNA gene. Monitoring for macrolide resistance is essential in infants <6 months of age. 相似文献
993.
E Macdonald BT Heier K Nygård T Stalheim KS Cudjoe T Skjerdal AL Wester BA Lindstedt TL Stavnes L Vold 《Emerging infectious diseases》2012,18(9):1496-1499
In 2011, an outbreak of illness caused by Yersinia enterocolitica O:9 in Norway was linked to ready-to-eat salad mix, an unusual vehicle for this pathogen. The outbreak illustrates the need to characterize isolates of this organism, and reinforces the need for international traceback mechanisms for fresh produce. 相似文献
994.
F Laurent H Chardon M Haenni M Bes ME Reverdy JY Madec E Lagier F Vandenesch A Tristan 《Emerging infectious diseases》2012,18(9):1465-1467
We describe human cases and clustered animal cases of mecA(LGA251)-positive methicillin-resistant Staphylococcus aureus in France. Our report confirms that this new variant has a large distribution in Europe. It may represent a public health threat because phenotypic and genotypic tests seem unable to detect this new resistance mechanism. 相似文献
995.
Kamiya H Otsuka N Ando Y Odaira F Yoshino S Kawano K Takahashi H Nishida T Hidaka Y Toyoizumi-Ajisaka H Shibayama K Kamachi K Sunagawa T Taniguchi K Okabe N 《Emerging infectious diseases》2012,18(7):1166-1169
We describe the epidemiology of a pertussis outbreak in Japan in 2010-2011 and Bordetella holmesii transmission. Six patients were infected; 4 patients were students and a teacher at the same junior high school. Epidemiologic links were found between 5 patients. B. holmesii may have been transmitted from person to person. 相似文献
996.
997.
Barry PM Gardner TJ Funk E Oren E Field K Shaw T Langer AJ 《Emerging infectious diseases》2012,18(1):113-116
In 2008, diagnosis and investigation of 2 multidrug-resistant tuberculosis cases with matching genotypes led to identification of an outbreak among foreign-born persons who performed short-term seafood production work in Alaska during 2006. Tuberculosis control programs should consider the possibility of domestic transmission even among foreign-born patients. 相似文献
998.
Bergeron CR Prussing C Boerlin P Daignault D Dutil L Reid-Smith RJ Zhanel GG Manges AR 《Emerging infectious diseases》2012,18(3):415-421
We previously described how retail meat, particularly chicken, might be a reservoir for extraintestinal pathogenic Escherichia coli (ExPEC) causing urinary tract infections (UTIs) in humans. To rule out retail beef and pork as potential reservoirs, we tested 320 additional E. coli isolates from these meats. Isolates from beef and pork were significantly less likely than those from chicken to be genetically related to isolates from humans with UTIs. We then tested whether the reservoir for ExPEC in humans could be food animals themselves by comparing geographically and temporally matched E. coli isolates from 475 humans with UTIs and from cecal contents of 349 slaughtered animals. We found genetic similarities between E. coli from animals in abattoirs, principally chickens, and ExPEC causing UTIs in humans. ExPEC transmission from food animals could be responsible for human infections, and chickens are the most probable reservoir. 相似文献
999.
1000.
Sequencing of the 16S rRNA gene (16S) is a reference method for bacterial identification. Its expanded use has led to increased recognition of novel bacterial species. In most clinical laboratories, novel species are infrequently encountered, and their pathogenic potential is often difficult to assess. We reviewed partial 16S sequences from >26,000 clinical isolates, analyzed during February 2006-June 2010, and identified 673 that have <99% sequence identity with valid reference sequences and are thus possibly novel species. Of these 673 isolates, 111 may represent novel genera (<95% identity). Isolates from 95 novel taxa were recovered from multiple patients, indicating possible clinical relevance. Most repeatedly encountered novel taxa belonged to the genera Nocardia (14 novel taxa, 42 isolates) and Actinomyces (12 novel taxa, 52 isolates). This systematic approach for recognition of novel species with potential diagnostic or therapeutic relevance provides a basis for epidemiologic surveys and improvement of sequence databases and may lead to identification of new clinical entities. 相似文献