全文获取类型
收费全文 | 2832篇 |
免费 | 56篇 |
国内免费 | 45篇 |
专业分类
耳鼻咽喉 | 42篇 |
儿科学 | 83篇 |
妇产科学 | 306篇 |
基础医学 | 154篇 |
口腔科学 | 80篇 |
临床医学 | 342篇 |
内科学 | 137篇 |
皮肤病学 | 25篇 |
神经病学 | 47篇 |
特种医学 | 95篇 |
外科学 | 286篇 |
综合类 | 631篇 |
预防医学 | 255篇 |
眼科学 | 10篇 |
药学 | 325篇 |
7篇 | |
中国医学 | 72篇 |
肿瘤学 | 36篇 |
出版年
2024年 | 2篇 |
2023年 | 33篇 |
2022年 | 34篇 |
2021年 | 63篇 |
2020年 | 49篇 |
2019年 | 57篇 |
2018年 | 37篇 |
2017年 | 51篇 |
2016年 | 60篇 |
2015年 | 92篇 |
2014年 | 203篇 |
2013年 | 204篇 |
2012年 | 217篇 |
2011年 | 239篇 |
2010年 | 231篇 |
2009年 | 193篇 |
2008年 | 146篇 |
2007年 | 167篇 |
2006年 | 148篇 |
2005年 | 120篇 |
2004年 | 101篇 |
2003年 | 82篇 |
2002年 | 55篇 |
2001年 | 54篇 |
2000年 | 39篇 |
1999年 | 22篇 |
1998年 | 24篇 |
1997年 | 28篇 |
1996年 | 14篇 |
1995年 | 20篇 |
1994年 | 13篇 |
1993年 | 17篇 |
1992年 | 10篇 |
1991年 | 10篇 |
1990年 | 19篇 |
1989年 | 11篇 |
1988年 | 6篇 |
1987年 | 9篇 |
1986年 | 4篇 |
1985年 | 6篇 |
1984年 | 7篇 |
1983年 | 3篇 |
1982年 | 7篇 |
1981年 | 3篇 |
1980年 | 5篇 |
1979年 | 5篇 |
1978年 | 2篇 |
1977年 | 4篇 |
1972年 | 2篇 |
1971年 | 2篇 |
排序方式: 共有2933条查询结果,搜索用时 31 毫秒
101.
Carneiro FP de Nazareth Sobreira M de Azevedo AE Alves AP Campos KM 《World journal of gastroenterology : WJG》2008,14(6):966-968
Duplications of the alimentary tract are uncommon congenital malformations that can present diagnostic difficulties. We report a rare case of a cystic colonic duplication in a female adult. Preoperative investigations were suggestive of pancreatic tumor. The diagnosis was established based on the histopathological examination of the resected specimen. We concluded that, though uncommon, intestinal duplication should be considered in differential diagnosis of abdominal mass. 相似文献
102.
胆囊浆膜面异位肝组织1例 总被引:10,自引:0,他引:10
病例资料:患者,男,38岁。因体检B超检查发现胆囊息肉,于2005年11月21日入院。入院检查:生命体征正常,全身皮肤及巩膜无黄染,浅表淋巴结无肿大,腹平软,无压痛及反跳痛,肝脾肋下未触及。实验室检查:血、尿、粪常规正常,肝、肾功能正常 。 相似文献
103.
目的:探讨经腹部B超检查和经阴道B超检查在诊断孕妇异位妊娠中的临床价值。方法:选取2011年1月-2013年10月来本院就诊且确诊的异位妊娠患者126例作为研究对象,将其按随机数字表法分为经腹部B超检查组和经阴道B超检查组,每组63例,利用HD7彩色超声诊断仪分别进行腹部B超检查和阴道B超检查,根据B超诊断标准,以确定两种方法的诊断符合率。结果:经腹部B超检查组的诊断符合率为74.61%,经阴道B超检查组为95.24%,差异有统计学意义(P〈0.05);在超声图像的各种指标检出率方面,经阴道B超检查组均明显优于经腹部B超检查组,差异有统计学意义(P〈0.05)。结论:与经腹部B超检查相比,经阴道B超检查的优势更为明显:诊断符合率高、快速、简便,更值得在临床上推广。 相似文献
104.
目的研究分析采用腹腔镜手术治疗异位妊娠合并失血性休克的临床治疗效果。方法选择我院2011年12月—2013年12月收治的80例异位妊娠合并失血性休克患者作为研究对象,将所有患者按照数字随机发分为观察组和对照组两组,每组各40例。观察组采取腹腔镜手术治疗,而对照组采取常规开腹手术治疗。观察对比两组患者在手术时间、腹腔内出血量、需镇痛例数情况、肛门排气时间以及住院时间情况。结果观察组患者手术时间为(40.6±20.2)min,肛门排气时间(10.1±4.2)h,住院时间为(4.5±1.4)d,均明显短于对照组的(63.8±23.1)min、(20.3±5.4)h和(6.4±1.7)d,差异具有统计学意义(P〈0.05)。观察组在术后无需要镇痛患者,对照组有12例,差异具有统计学意义(P〈0.05)。两组患者在腹腔内出血量情况的差异没有统计学意义(P〉0.05)。结论对于异位妊娠合并失血性休克患者采取腹腔镜手术治疗效果显著,能够有效减少术后镇痛,缩短肛门排气时间与住院时间,值得临床推广运用。 相似文献
105.
目的探讨米非司酮联合中药方剂治疗异位妊娠的临床疗效。方法依据随机原则,将该院收治的60例宫外孕患者分为两组,治疗组(30例)采用米非司酮联合中药方剂(宫外孕Ⅱ号)治疗,对照组(30例)给予单纯米非司酮治疗。观察两组治愈效果及临床症状改善情况。结果治疗组治愈率为96.67%,对照组治愈率为73.34%,两组比较具有统计学意义(P〈0.05);两组血HCG下降值(3 d,U/L)、血HCG值恢复正常时间及妊娠包块消失时间治疗组和对照组分别为(210.57±24.38)U/L和(187.86±25.43)U/L;(18.46±11.15)d和(28.38±12.64)d;(36.19±16.28)d和(49.24±17.07)d,分析比较有统计学意义(P〈0.05)。结论米非司酮联合中药方剂治疗异位妊娠疗效满意,且能够有效改善临床症状,是理想的治疗方法。 相似文献
106.
《Journal of cranio-maxillo-facial surgery》2019,47(8):1274-1279
Restoration of the mandible after defects caused by ablative surgery remains challenging. Microvascular free flaps from the scapula, fibula or iliac crest remain the ‘gold standard’. A drawback of these methods is donor-side morbidity, availability and the shape of the bone. Former cases have shown that prefabrication of a customized bone flap in the latissimus dorsi muscle may be successful; however, this method is still associated with high donor-side morbidity. Osteogenesis in the omentum majus of rabbits by wrapping the periosteum into it was confirmed recently and is particularly interesting for bone endocultivation.Twelve adult male New Zealand white rabbits were used. In each, two hydroxyapatite blocks were implanted in the greater omentum with autologous bone or autologous bone + rhBMP-2.Bone density measurements were performed by CT scans. Fluorochrome labelling was used for new bone formation detection. The animals were sacrificed at week 10, and the specimens were harvested for histological and histomorphometric analysis. In histological and fluorescence microscopic analysis, new bone formation could be found, as well as new blood vessels and connective tissue. No significant differences were found regarding the histological analysis and bone density measurements between the groups.It could be demonstrated that the omentum majus is a practical way to use one's own body as a bioreactor for prefabrication of tissue-engineered bony constructs. Regarding the influence and exact dose of rhBMP-2, further research is necessary. To establish and improve this method, further large-animal experimental studies are also necessary. 相似文献
107.
目的探讨介入栓塞治疗继发性肾源性异位甲状旁腺功能亢进的有效性、安全性及可行性。
方法术前通过高频超声、99mTc-MIBI甲状旁腺核素显像、增强CT或增强MRI检查评估异位甲状旁腺的解剖位置及动脉血供情况,采用介入栓塞的方式阻断其供血动脉,从而使其逐渐缺血坏死失去功能。
结果第1例患者的异位甲状旁腺通过介入栓塞治疗后,其甲状旁腺素(parathyroid hormone,PTH)水平迅速下降,血钙、血磷亦迅速下降,皮肤瘙痒、周身骨痛等临床症状明显缓解;第2例患者因供血动脉显示不清,加之术中难以配合,仅完成部分血管栓塞,其PTH、血钙、血磷等指标呈一过性下降,但最终疗效不佳。
结论介入栓塞治疗异位甲状旁腺是一种创伤小、操作简便、疗效相对可靠、安全性高的方法,成功的关键是术前明确定位及供血动脉,术中尽量完全栓塞其供血动脉,但其长期有效性尚需进一步评价。 相似文献
108.
目的:探讨宫内节育器异位的原因、诊断方法,分析IUD异位的危险因素、处理方法。方法回顾性分析42例节育器异位的临床资料。结果爱母环占61.90%(26/42),O形环占28.57%(12/42),T环形占4.76%(21/42),吉妮环占4.76%(2/42);爱母环发生异位的机率明显高于其它类型节育器;位于子宫肌层内30例,穿破浆膜层4例;子宫外异位:位于盆腔内6例,阔韧带后叶3例;爱母环的一条金属臂穿入乙状结肠1例,穿入宫旁1例,1例位于右上腹大网膜内,1例位于肠管表面。取器方式利用宫腔镜、腹腔镜、宫腹腔镜联合、膀胱镜及开腹等方式,均成功。有随访记录的14例占33.4%,其中,术后1+月随访3例占7.1%,1年内随访者有12例占21.4%,3年内随访者2例占4.8%,无随访者28例占66.7%。节育环异位穿孔率无随访者高于有随访记录者。在节育器异位患者中,上环后有再次妊娠15例占35.7%。结论选择合适的节育器,适宜的安环时间可减少节育器异位的发生。充分术前评估,选择适宜的手术方式、及时、合理转换术式是取环成功的关键。 相似文献
109.
María Sol Ruiz Soledad Mac Keon Sabrina Campisano Alicia Inés Bravo Silvina Gazzaniga Rosa Wainstok 《Vaccine》2014
De novo ectopic lymphoid tissue formation is known to occur in certain disease and inflammatory settings. After an effective vaccination with dendritic cells (DC) charged with melanoma apoptotic/necrotic cells (Apo/Nec), a subcutaneous tertiary lymphoid structure was organized, where retained vaccine cells interacted with recruited inflammatory and T cells. In this work we report for the first time the recruitment of two morphologically different CD207+ cells to vaccination site. The time-course behavior of CD207+ cells was reciprocal between vaccination site and draining lymph nodes (DLNs). After 6–10 days, CD207+ cells localized at the paracortical region of DLNs, in close contact with T cell population. DLNs were enriched in a peculiar MHCII+ CD11c(−) CD207+ population, whose role remains to be determined. Whether CD207+ cells migration to the vaccination site can be associated with a differential anti-tumoral response remains as an open and exciting question. 相似文献
110.
Objective: To evaluate the periodontal health and tooth vitality of palatally impacted and buccal ectopic maxillary canines after completion of orthodontic treatment.Materials and Methods:Fifteen patients who had unilateral, palatally impacted canines and 15 patients who had unilateral, buccal ectopic canines comprised the subjects of the study. Clinical and radiographic data was collected by recalling the patients in both groups after a mean period of 3.82 ± 1.54 years following completion of their orthodontic treatment. In both groups, the contralateral, normally placed canines served as controls.Results:Palatally impacted canines had greater pocket depths, higher gingival levels, higher electric pulp testing scores, and reduced bone levels compared to their contralaterals. Buccal ectopic canines had increased plaque and gingival bleeding index, greater pocket depths, reduced attached gingival width, higher gingival levels, increased clinical crown lengths, and higher electric pulp testing scores compared to their contralaterals. Buccal ectopic canines had lower electric pulp testing scores and higher bone levels compared to palatally impacted canines.Conclusion:All ectopic canines had increased plaque and gingival bleeding index, greater pocket depths, reduced attached gingival width, higher gingival levels, increased crown lengths, higher electric pulp testing scores, and reduced bone levels compared to their contralaterals. 相似文献