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101.
[背景 ]总结分析先天性肥厚性幽门狭窄临床诊断、治疗经验及影响治疗的相关因素 .[病例报告 ]回顾 1990~ 1999年收治的先天性肥厚性幽门狭窄 2 0例 ,对其临床表现、诊断以及治疗进行分析 .2 0例中手术治疗 18例 ,其中 3例幽门十二指肠交界处粘膜在术中破裂 ,修补后覆盖大网膜 ,术后无 1例消化道瘘 .[讨论 ]先天性肥厚性幽门狭窄患儿在生后 3~ 4周出现呕吐症状 .根据典型的临床表现和X线钡餐透视可确定诊断 ,及时发现并修补破裂的粘膜可防止消化道瘘 .术后少量多次输血对患儿早日康复大有益处 相似文献
102.
早期口服祛黄汤防治新生儿黄疸的临床研究 总被引:8,自引:0,他引:8
目的 为降低新生儿黄疸减少高胆红素血症发生,我们采用早期口服祛黄汤的方法,观察其对新生儿黄疸的影响,将出生后新生儿随机分为实验组100例,常规处理后于6小时内口服祛黄汤,连服3日。对照组100例,不服用任何药物。结果 新生儿生后6小时内第一次排便例数实验组明显高于对照组;新生儿第一次大便变黄时间,实验组较对照组明显缩短;4日龄新生儿黄染的例数、程度实验组明显低于对照组;血胆红素浓度实验组明显低于对 相似文献
103.
目的 :了解新生儿缺氧缺血性脑病 (HIE)时血浆和脑脊液 (CSF)中 NO水平的动态变化。方法 :采用硝酸根还原酶法 ,对 35例 HIE患儿 (轻度 10例、中度 13例、重度 12例 )分别于急性期、恢复期进行了血浆和 CSF NO水平测定。结果 :HIE急性期血浆 NO水平除轻度组外 ,中、重度组明显高于对照组 ,重度组又明显高于轻、中度组 ;恢复期轻、中、重度组血浆 NO水平均降至正常 ,与对照组比较差异无显著性。CSF中 NO水平增加的幅度与血浆成正比。结论 :血浆和 CSF中 NO水平与 HIE的脑损伤程度密切相关 相似文献
104.
AB-type amphiphilic copolymers (abbreviated as LE) composed of poly (L-leucine) (PLL) as the A component and poly (ethylene
oxide) (PEO) as the B component were synthesized by the ring-opening polymerization of L-leucine N-carboxy-anhydride initiated
by methoxy polyoxyethylene amine (Me-PEO-NH2) and characterized. Core-shell type nanoparticles were prepared by the diafiltration method. Particle size distribution obtained
by dynamic light scattering was dependent on PLL composition and the size for LE-1, LE-2 and LE-3 was 369.6±267, 523.4±410
and 561.2±364 nm, respectively. Shapes of the nanoparticles observed by transmission electron microscope (TEM) were almostly
spherical. The critical micelle concentration (CMC) of the nanoparticles determined by a fluorescence probe technique was
dependent on the composition of hydrophobic PLL, and the CMC for LE-1, LE-2 and LE-3 was 2. 0×10−6, 1.7×10−6 and 1.5×10−6 (mol/l), respectively. Clonazepam release from core-shell type nanoparticles in vitro was dependent on PLL composition and
drug loading content. 相似文献
105.
106.
1994年初我校妇产科学教研室引进了体外受精-胚胎移植(IVF-ET)术,1995年1月5日山东省首例“试管婴儿”在山东省立医院出生。作者详述了实施IVF-ET的经过。此项技术的应用成功为开展生殖生理学、遗传学和优生学研究及临床应用奠定了基础。 相似文献
107.
新生儿严重脑室内出血连续腰穿的疗效 总被引:16,自引:0,他引:16
目的为了治疗和预防脑室内出血后脑积水的发生和发展,改善新生儿严重脑室内出血的不良预后。方法1989年以来,对19例在出生后早期经头颅B超诊断为严重脑室内出血(IVH)患儿进行了连续腰穿(LP)治疗。结果有效16例,自动出院1例,失败2例。有效率为84.2%。有效16例初次LP日龄为14.6±5.7d,疗程23.4±12d,平均LP次数9.3±4.7次,平均LP间隔期3.1±1.6d,平均每次放液量6.7±2ml,LP治疗后起效天数为10.1±7.8d。2例在连续LP的同时联用乙酰唑胺治疗亦取得显著疗效。16例平均随访月龄为3.2±1月,体格发育均正常,B超显示12例脑室形态正常,4例脑室呈稳定的轻度增大。失败的2例初次LP迟,初期LP间隔期延长为7-9d,放液量<5ml。同期另有17例严重IVH患儿未予LP治疗。其中4例并发脑积水,5例自动出院,4例早期死亡,余4例其后脑室形态稳定。结论连续LP不失为治疗新生儿严重IVH实用安全有效的方法,LP疗效欠佳时可联用乙酰唑胺治疗。 相似文献
108.
目的:探讨新生儿通气相关性肺炎病因、病原菌、耐药情况、相关防治措施。方法:分析103 例新生儿通气相关性肺炎患儿痰培养结果、诊治情况。结果:醋酸不动杆菌、铜绿假单胞菌、肺炎克雷伯杆菌是三种主要致病菌,耐药率高,对泰能、环丙沙星最为敏感。结论:革兰阴性杆菌是新生儿通气相关性肺炎重要病原菌,耐药率高,治疗较为困难,应积极预防。 相似文献
109.
Venoarterial extracorporeal membrane oxygenation (ECMO) was performed in five dogs without systemic heparinization to assess the feasibility of heparin-free ECMO. The surfaces of the inverted hollow-fiber-type oxygenator and circuit of the ECMO system were coated with heparin by the endpoint-attached (covalent-bonded) technique. No heparin was administered to the animal except for a small dose to maintain patency of the arterial line (1 IU/h). ECMO was run for 24 h at a pump flow of 50 ml/kg · min and was successful throughout the experiment in four of the five dogs. Scanning electron microscopy did not detect any blood clots in the oxygenator or circuit except for inside and outside the cannulas that were not coated with heparin in the carotid artery and jugular vein. Activated clotting time (ACT), fibrinogen, and anti-thrombin III (AT-III) activity remained within the normal physiological range. Serum heparin concentrations were low throughout the experiment, indicating minimal heparin release. Platelet levels decreased and fibrinopeptide B 15–42 (FPB 15–42) increased significantly after 6 h ECMO. D-dimer levels did not change throughout the experiment. ECMO was discontinued in one case after successful a 23-h run because of macroscopic clot formation at the oxygenator blood inlet. ACT had suddenly increased to 160 s approximately 1 h prior to this clot formation. These results suggest that the amount of systemic heparinization required can be substantially reduced by a heparin-coated ECMO system. Total abolishment of heparin administration in pediatric venoarterial ECMO may be possible by refinement of this technique. Monitoring of AT-III and FPB 15–42 in addition to ACT may be useful for early diagnosis of latent but ongoing coagulopathies during ECMO. 相似文献
110.
Adenohypophyses of human newborns contain characteristic psammoma bodies. Their numbers are maximal within 2 weeks of the
neonatal period and diminish thereafter. They are very rare in infant pituitaries, seeming to disappear by shrinkage in that
there is a significant direct correlation between their number and size. The bodies were found to contain a high concentration
of endogenous peroxidase, thus suggesting that the enzyme may be responsible for their disappearance. A statistical majority
of psammoma bodies were located within follicular lumens. By immunohistochemistry, the follicular epithelium surrounding psammoma
bodies showed immunoreactivity for various pituitary hormones. Light microscopy demonstrated that adenohypophysial cells surrounding
psammoma bodies contain randomly, scattered granules or globules exhibiting peroxidase activity. Extrusion of such granules
into follicular lumens may play a role in the genesis of the concretions. The conspicuous lamellar nature of the calcified
psammoma bodies suggests that waves of calcium deposition occur during their morphogenesis. Despite histologic similarities,
the histochemical characteristics of this type of psammoma body differ from those in other organs as well as from the calcification
encountered in prolactin (PRL)-producing pituitary adenomas. 相似文献