霉菌性鼻窦炎的CT诊断

目的探讨霉菌性鼻窦炎CT特征性表现及诊断价值。方法回顾性分析25例经手术病理证实的霉菌性鼻窦炎CT表现。结果25例主要CT表现为病变均为单侧性,位于上颌窦或以上颌窦为主,累及其他鼻窦;病变窦腔密度不均匀增高,内有局灶性点状、絮状(9例),砂粒状、小斑片状(16例)高密度影;可有窦壁骨质破坏(13例)。结论霉菌性鼻窦炎在CT表现有特异性,CT对该病的诊断有很高的价值。     

肛瘘的挂线治疗

肛瘘是常见的外科难治性疾病,治疗的主要目的是引流脓液,根治瘘管,保护括约肌的完整性和肛门功能。大多数低位肛瘘可以通过切开或切除就可以达到根治的目的。同时肛门功能也能得到保护。因为低位瘘管仅累及括约肌的下1/3。但高位复杂性肛瘘的处理仍比较棘手,当瘘管经过肛管括约     

经尿道电切治疗小体积前列腺增生36例

我院自2002年以来对经B超测量体积在30 mL以下的小体积前列腺行经尿道前列腺电切术(transurethral resection of prostate,TURP) 经尿道膀胱颈部切开术(transurethral incision of bladder neck,TUIBN),随访3～6月效果满意,报告如下.……     

人抵抗素基因cDNA的克隆

目的克隆人抵抗素基因(hRETN)cDNA,为进一步研究RETN的结构和功能提供实验基础.方法应用RT-PCR方法从中国人网膜脂肪垫总RNA中扩增出RETN 基因cDNA,克隆入载体pMD18-T中,形成重组载体pMD18-T/hRETN.通过蓝白斑筛选出阳性克隆,限制性内切酶酶切鉴定后对其进行测序.结果从脂肪组织总RNA中扩增得到363 bp片段hRETN基因,其cDNA序列与Genbank hRETN基因序列基本相同.结论成功地克隆中国人hRETN cDNA.     

经皮穿刺腰椎间盘切除术的护理

<正>自1975年GIJAKATA首次采用经皮穿刺腰椎间盘切除术(PLD)治疗腰椎间盘突出症并取得较好疗效后,这一介入手术被推广应用于临床,我院1998~2002年对180例腰椎间盘突出患者进行PLD的治疗,取得满意疗效。报告如下。     

腹腔镜胆总管切开取石术后内置管引流与T管引流临床研究

目的 :比较分析腹腔镜胆总管切开取石术后内置管引流与T管引流两种方法对患者康复的影响。方法 :回顾性总结分析 1999年以来行腹腔镜胆总管切开取石术后内置管引流的 2 6例患者临床疗效 ,并与同期行T管引流的 31例患者进行了比较。结果 :内置管引流组术后无胆汁丢失 ,较T管引流组痛苦小、胃肠功能恢复快。两组比较 ,手术时间无明显差异 ,术后开始进食时间分别为 13.8± 3.4,35 .5± 6 .8h ,(P <0 .0 5 ) ,恢复肠蠕动时间为 30 .5± 5 .6 ,43.8± 7.4h ,(P <0 .0 5 ) ,抗生素平均使用天数 3.5± 0 .6 ,6 .4± 1.1d ,(P <0 .0 5 ) ,术后输液量 45 5 0± 5 84,135 0 0± 12 5 0ml,(P <0 .0 1) ,术后平均住院日 4.6± 1.7,9.6± 2 .4d ,(P <0 .0 1) ,平均住院费用 815 0± 910 ,5 0 0± 12 70元 (P <0 .0 5 ) ,恢复日常工作时间 12 .8± 2 .5 ,2 7.4± 6 .9d ,(P <0 .0 5 )。结论 :腹腔境胆总管探查、内置管引流术后胆总管一期缝合避免了T管引起的并发症 ,大大减轻了患者的痛苦 ,缩短了输液时间和住院时间 ,减少了抗生素的用量 ,值得推广应用。     

三维液体刀在腰椎间盘突出症的治疗应用129例报告

目的 探讨一种腰椎间盘突出症(LDH)非手术的治疗方法。方法 在临床工作中采用三维正脊加骶管封闭(称为三维液体刀疗法)治疗腰椎间盘突出症129例。结果 129例患者采用三维液体刀治疗后，进行3个月～1年6个月的随诊，其中显效110例(85．27％)，有效17例(13．28％)，总有效率98．45％，疗效满意。结论 三维液体刀使腰椎间盘突出部分和受刺激的神经根的炎症水肿加速消退，从而减轻或解除对神经根的压迫，是一种快速有效的非手术治疗方法，值得临床推广应用。     

环戊硫酮治疗干眼的临床疗效评价

Objective To investigate anethol trithione therapic efficiency on dry eye. Methods It was a prospective random double-blind controlled study. Eighty cases diagnosed dry eye in Ocular Surface Out-patient Clinic of Xiamen University Affiliated Xiamen Eye Center from 2006 to 2008 were divided into two groups: anethol trithione group and control group, 40 cases in each group. Every group was then divided into two subgroups: weak dry eye subgroup, middle and severe dry eye subgroup. All groups had been added with 0.05% refresh drops. All patients had been detected and evaluated by subjective symptoms of dry eye, visual acuity,corneal fluorescent staining(F1), break-up time(BUT) and Schirmer Ⅰ test (SⅠT) at pre-therapy and 3,7,28 d of post-therapy. All groups had been compared and analyzed by F test and sample mean difference (SMD) or median difference (MD) comparison between pre-therapy and post-therapy. Results Except of tear and red eye, the other subjective symptoms of dry eye, F1, BUT and SⅠT of weak dry eye subgroup of both groups had been improved at 7 d after therapy. Only those of middle and severe dry eye subgroup of anethol trithione group had been improved at 7 d after therapy compared with those of pre-therapy: SMD=0.96 (visual tiredness), 1.26 (dry and unsmooth sensation), 0.82 (foreign body sensation), 1.28 (burning sensation), 1.05 (photophobia), 1.48 ( pain ) ; MD=0.30 (visual acuity), 4.00 (F1) ,5.00 (BUT), 5.00 (SⅠT) [F=15.30 (visual tiredness), 15.68 (dry and unsmooth sensation ), 13.56 (foreign body sensation), 20. 91 ( burning sensation ), 18.90 (photophobia), 27.22 ( pain ), 10.54 (visual acuity), 188.21 (F1) ,261.76 (BUT) ,269.05 (SⅠT) ;P<0. 05]. Those of middle and severe dry eye subgroup of control group hadn't significantly been improved at 28 d after therapy: SMD=0.10 (visual tiredness) ,0.16 (dry and unsmooth sensation) ,0.09 (foreign body sensation) ,0.38 ( burning sensation ), 0.24(photophobia) ,0.36 (pain) ,0.23 (red eye) ; MD=0.10 (visual acuity) ,0.50(F1) ,0.50(BUT), 0.50(SⅠT) [F=1.76 (visual tiredness), 1.61 (dry and unsmooth sensation), 1.02 (foreign body sensation),2.39 (burning sensation), 2.42 (photophobia), 2.73 ( pain ), 2.55 ( red eye ), 1.46 ( visual acuity) ,2.35 (F1) ,2.90 (BUT) ,2.76 (SⅠT) ; P>0.05]. SⅠT of anethol trithione group had been improved more significantly after therapy (F=13.77, P<0.05). Conclusion Anethol trithione could significantly improve middle and severe dry eye patients' symptoms and signs whose lacrimal gland function survival and it has clinical application value.     

L-肌肽对大鼠硒性白内障的影响

Objective To explore the effect of L-canosine in preventing and treating rat cataract induced by sodium selenite. Methods This was an experimental study. Cataract was induced in the rats by sodium selenite. Rats were divided into 3 groups and each group has 3 ones. L-canosine eye drops (50 g/L or 20 g/L) and 0.9% normal saline were respectively instilled to the rat eye for 3 weeks and examined. L-canosine was added to the medium of cultured rat cataract lens at 1.00, 0.10 and 0.01 g/L for 1 week and then examined. Cataract lens were studied by using two-dimensional eletrophoresis. Results One week after instillation of L-canosine, the scores of rat cataract were 2.22±0.65, 2.39±0.98 and 2.83±0.38 in 50 g/L, 20 g/L L-canosine and control groups, respectively. The lesion in 50 g/l, L-canosine group was lighter than that of the control group. There was significant difference between these two groups (P=0.013). On the 2nd and 3rd weeks, there was no difference among these three groups. After 1 week for culturing cataract lens, there was no difference between these three groups. The results of two-dimensional eletrophoresis showed that the protein number was 182 and 161 in the L-carnosine and control groups, respectively. High molecular weight protein decreased and low molecular weight protein increased in L-carnosine group. Conclusions L-carnosine at 50 g/L could restrain the development of early stage rat cataract. L-camosine could modulate the rat lens protein in vitro, but could not affect lens cataract scores.     

丁胺卡那雾化吸入预防绿脓杆菌致下呼吸道感染的临床观察

为预防重症监护病房(ICU)绿脓杆菌(铜绿假单胞菌)引起下呼吸道感染，我们对我院ICU内气管切开病人进行丁胺卡那持续氧气雾化吸入。经临床观察效果满意，现报告如下。