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51.
52.
H.L. Fung J. Calzada A. Saldaña A.M. Santamaria V. Pineda K. Gonzalez L.F. Chaves B. Garner N. Gottdenker 《Acta tropica》2014
Dogs play an important role in infectious disease transmission as reservoir hosts of many zoonotic and wildlife pathogens. Nevertheless, unlike wildlife species involved in the life cycle of pathogens, whose health status might be a direct reflection of their fitness and competitive abilities, dog health condition could be sensitive to socio-economic factors impacting the well-being of their owners. Here, we compare several dog health indicators in three rural communities of Panama with different degrees of socio-economic deprivation. From a total of 78 individuals, we collected blood and fecal samples, and assessed their body condition. With the blood samples, we performed routine hematologic evaluation (complete blood counts) and measured cytokine levels (Interferon-γ and Interleukin-10) through enzyme-linked immunosorbent assays. With the fecal samples we diagnosed helminthiases. Dogs were also serologically tested for exposure to Trypanosoma cruzi and canine distemper virus, and molecular tests were done to assess T. cruzi infection status. We found significant differences between dog health measurements, pathogen prevalence, parasite richness, and economic status of the human communities where the dogs lived. We found dogs that were less healthy, more likely to be infected with zoonotic pathogens, and more likely to be seropositive to canine distemper virus in the communities with lower economic status. This study concludes that isolated communities of lower economic status in Panama may have less healthy dogs that could become major reservoirs in the transmission of diseases to humans and sympatric wildlife. 相似文献
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54.
《Clinical and experimental hypertension (New York, N.Y. : 1993)》2013,35(4):663-691
A dissociation between changes in blood pressure (BP) and plasma renin activity (PRA) has been noted after administration of renin inhibitors. In the present study, the renin inhibitor PD 132002 was given to salt-deplete, anesthetized dogs. PRA was measured at pH 6.0 by a conventional angiotensin I (ANG I) RIA method (PRA-C) and by an ANG I antibody-trapping RIA method (PRA-AT) performed at pH 7.4. PD 132002 at 0.01, 0.1, 1, and 10 mg/kg IV, reduced BP by 3 ±2, 9 ± 2, 24 ± 4, and 39 ± 4 mm Hg, respectively, (baseline of 136 ± 8 mm Hg, N = 5) 相似文献
55.
56.
宁夏西吉县人体两种肝包虫病调查的初步报告 总被引:2,自引:2,他引:2
采用梯度筛选后B超检查,对西吉县农民、城镇人员患肝泡球蚴病(LAE)和肝棘球蚴病(LCECE)的情况进行调查。共检查2 389人,检出肝包虫病患者197例,患病率为8.2%,其中LAE 141例,占5.9%;LCR 56例,占2.3%。农民LAE和LCE患病率分别为9.7%和3.8%。城镇的分别为0.4%和0.2%。农民患病率高。LAE与猎狐、捕捉达乌尔黄鼠有密切关系。家犬是LCE的传染源。 相似文献
57.
Torahiko Takeda Hiroki Tohma Junichi Yoshida Gen Naritomi Hiroyuki Konomi Zhou-Lu Deng Naoko Kinukawa Masao Tanaka 《Journal of gastroenterology》1998,33(6):860-863
The relationship between sphincter of Oddi pressure and the morphological structure of the sphincter was studied in eight
dogs prepared with a duodenal cannula. Sphincter of Oddi manometry was performed in awake animals in three directions, ventral,
left dorsal, and right dorsal, using a catheter with three radial side holes for recording at one level. The pressure in the
ventral direction (26.6 ± 1.06 mmHg) (mean ± SEM) was significantly lower than that in the left and right dorsal directions
(30.6 ± 1.42 and 31.2 ± 1.23 mmHg, respectively). This functional manometric difference in the three directions correlated
closely with the morphological structure of the sphincter of Oddi; the sum of the thickness of the sphincter of Oddi muscle
and duodenal proper muscle was greater on the dorsal than on the ventral side. To our knowledge, this is the first report
of axial asymmetry in sphincter of Oddi pressure.
(Received May 27, 1997; accepted April 24, 1998) 相似文献
58.
Dr. Masafumi Kogire MD Kazutomo Inoue MD Shoichiro Sumi MD Ryuichiro Doi MD Mitsutoshi Yun MD Hiromu Kaji MD Takayoshi Tobe MD 《Digestive diseases and sciences》1992,37(11):1666-1670
Gastric inhibitory polypeptide (GIP) has considerable structural homology with glucagon, which is known to increase liver blood flow. We compared the effects of GIP on portal venous and hepatic arterial flow with those of glucagon in conscious dogs. Injection of GIP significantly increased portal venous flow in a dose-related manner (by 7%, 15%, and 46% at doses of 1, 100, and 500 pmol/kg, respectively). The increase in portal venous flow induced by GIP and glucagon was comparable; however, the increase in portal venous flow after GIP injection reached its peak significantly earlier than that after glucagon injection. Hepatic arterial flow decreased after GIP injection (by 17%, 21%, and 35% at doses of 1, 100, and 500 pmol/kg, respectively), whereas it was not altered by glucagon. Thus, GIP causes significant changes in both portal venous and hepatic arterial flow in conscious dogs. Although structurally related, GIP and glucagon may influence liver blood flow through different mechanisms.Supported by a grant from the Ministry of Education, Japan (No. A-02404052) 相似文献
59.
Electrospun silk fibroin‐based neural scaffold for bridging a long sciatic nerve gap in dogs 下载免费PDF全文
Chengbin Xue Hui Zhu Dehua Tan Hechun Ren Xiaokun Gu Yahong Zhao Ping Zhang Zhichao Sun Yumin Yang Jianhui Gu Yun Gu Xiaosong Gu 《Journal of tissue engineering and regenerative medicine》2018,12(2):e1143-e1153
Silk fibroin (SF)‐derived silkworms represent a type of highly biocompatible biomaterial for tissue engineering. We have previously investigated biocompatibility of SF with neural cells isolated from the central nervous system or peripheral nerve system in vitro, and also developed a SF‐based nerve graft conduit or tissue‐engineered nerve grafts by introducing bone marrow mesenchymal stem cells, as support cells, into SF‐based scaffold and evaluated the outcomes of peripheral nerve repair in a rat model. As an extension of the previous study, the electrospun technique was performed here to fabricate SF‐based neural scaffold inserted with silk fibres for bridging a 30‐mm‐long sciatic nerve gap in dogs. Assessments including functional, histological and morphometrical analyses were applied 12 months after surgery. All the results indicated that the SF‐based neural scaffold group achieved satisfactory regenerative outcomes, which were close to those achieved by autologous nerve grafts as the golden‐standard for peripheral nerve repair. Overall, our results raise a potential possibility for the translation of SF‐based electrospun neural scaffolds as an alternative to nerve autografts into the clinic. 相似文献
60.
Dubao Yang Qingfeng Zhang Limei Zhang Hong Dong Zhihong Jing Zhan Li 《International journal of environmental health research》2015,25(2):207-213
The aim of this study was to carry out a survey for the presence of Giardia duodenalis infection in canine using ELISA and PCR and to identify risk factors for infection. Samples from 318 dogs’ feces living in nine cities in China were used in the present study. Each sample was tested for the presence of G. duodenalis-specific antigens using ELISA and 197 out of 318 samples were further examined for the presence of G. duodenalis using PCR. The overall rate of canines infected with giardiasis in the present study was 16.04?% and 15.22?% using ELISA and PCR, respectively. No significant difference was found between sex and Giardia positivity. Young dogs (up to one year) and living in communities were identified as risk factors for infection by multivariate logistic regression analysis. In conclusion, giardiasis in dogs was present in nine cities in China; as risk factors, young dogs (up to one year) and living in communities were of great significance. Giardia-infected canine should be treated for hygienic management to prevent transmission of the infection from dog to human. 相似文献