全文获取类型
收费全文 | 191091篇 |
免费 | 16638篇 |
国内免费 | 6559篇 |
专业分类
耳鼻咽喉 | 1827篇 |
儿科学 | 3489篇 |
妇产科学 | 2019篇 |
基础医学 | 25710篇 |
口腔科学 | 3316篇 |
临床医学 | 18221篇 |
内科学 | 24073篇 |
皮肤病学 | 1784篇 |
神经病学 | 7683篇 |
特种医学 | 5594篇 |
外国民族医学 | 78篇 |
外科学 | 19028篇 |
综合类 | 30459篇 |
现状与发展 | 12篇 |
一般理论 | 25篇 |
预防医学 | 11923篇 |
眼科学 | 4354篇 |
药学 | 18033篇 |
27篇 | |
中国医学 | 8179篇 |
肿瘤学 | 28454篇 |
出版年
2024年 | 262篇 |
2023年 | 2192篇 |
2022年 | 3797篇 |
2021年 | 6693篇 |
2020年 | 5958篇 |
2019年 | 6044篇 |
2018年 | 5943篇 |
2017年 | 5935篇 |
2016年 | 6316篇 |
2015年 | 6506篇 |
2014年 | 10381篇 |
2013年 | 11028篇 |
2012年 | 9689篇 |
2011年 | 11115篇 |
2010年 | 9594篇 |
2009年 | 9615篇 |
2008年 | 9552篇 |
2007年 | 10864篇 |
2006年 | 10004篇 |
2005年 | 9592篇 |
2004年 | 8331篇 |
2003年 | 7363篇 |
2002年 | 5669篇 |
2001年 | 5595篇 |
2000年 | 4551篇 |
1999年 | 4125篇 |
1998年 | 3034篇 |
1997年 | 2657篇 |
1996年 | 2630篇 |
1995年 | 2466篇 |
1994年 | 2135篇 |
1993年 | 1885篇 |
1992年 | 1642篇 |
1991年 | 1414篇 |
1990年 | 1177篇 |
1989年 | 1078篇 |
1988年 | 1048篇 |
1987年 | 803篇 |
1986年 | 601篇 |
1985年 | 700篇 |
1984年 | 700篇 |
1983年 | 445篇 |
1982年 | 550篇 |
1981年 | 461篇 |
1980年 | 402篇 |
1979年 | 336篇 |
1978年 | 281篇 |
1977年 | 229篇 |
1976年 | 246篇 |
1975年 | 157篇 |
排序方式: 共有10000条查询结果,搜索用时 46 毫秒
31.
Yang Liu Yanyan Gao Hengliang Liu Qi Chen Jinrui Ji Kailong Jia 《Arquivos brasileiros de cardiologia》2021,116(2):229
BackgroundDual antiplatelet therapy (DAPT) is the cornerstone treatment of acute myocardial infarction (AMI).ObjectiveThe present study aimed to investigate the efficacy and safety of triple antiplatelet therapy (TAPT) in elderly female patients with diabetes and ST segment elevation myocardial infarction (STEMI), who had undergone percutaneous coronary intervention (PCI).MethodsWe designed a randomized, single-blind study. Control group A (97 elderly male patients with diabetes and STEMI, whose CRUSADE scores were < 30) received aspirin, ticagrelor, and tirofiban. A total of 162 elderly female patients with diabetes and STEMI were randomly divided into two groups according to CRUSADE score. Group B (69 patients with CRUSADE score > 31) received aspirin and ticagrelor. Group C (93 patients with CRUSADE score < 30) received aspirin, ticagrelor and tirofiban. P values < 0.05 were considered statistically significant.ResultsCompared to the findings in group A, post-PCI Thrombolysis in Myocardial Infarction (TIMI) grade 3 blood flow and TIMI myocardial perfusion grade 3 were significantly less prevalent in group B (p < 0.05). When compared to groups A and C, the incidence of major adverse complications was significantly higher in group B (p < 0.05).ConclusionTAPT could effectively reduce the incidence of major complications in elderly female patients with diabetes and STEMI. However, close attention should be paid to hemorrhage in patients receiving TAPT. (Arq Bras Cardiol. 2020; [online].ahead print, PP.0-0) 相似文献
32.
33.
34.
35.
36.
《Vaccine》2020,38(3):570-577
IntroductionPediatric pneumococcal pneumonia complicated by parapneumonic pleural effusion/empyema (PPE/PE) remains a major concern despite general immunization with pneumococcal conjugate vaccines (PCVs).MethodsIn a nationwide pediatric hospital surveillance study in Germany we identified 584 children <18 years of age with bacteriologically confirmed PPE/PE from October 2010 to June 2018. Streptococcus pneumoniae was identified by culture and/or PCR of blood samples and/or pleural fluid and serotyped.ResultsS. pneumoniae was identified in 256 of 584 (43.8%) children by culture (n = 122) and/or PCR (n = 207). The following pneumococcal serotypes were detected in 114 children: serotype 3 (42.1%), 1 (25.4%), 7F (12.3%), 19A (7.9%), other PCV13 serotypes (4.4%) and non-PCV13 serotypes (7.9%). Between October 2010 and June 2014 serotype 1 (38.1%) and serotype 3 (25.4%) were most prevalent, whereas between July 2014 and June 2018 serotype 3 (62.7%) and non-PCV13 serotypes (15.7%) were dominant. Compared to children with other pneumococcal serotypes, children with serotype 3 associated PPE/PE were younger (median 3.2 years [IQR 2.1–4.3 years] vs. median 5.6 years [IQR 3.8–8.2 years]; p < 0.001) and more frequently admitted to intensive care (43 [89.6%] vs. 48 [73.8%]; p = 0.04). Seventy-six of 114 (66.7%) children with pneumococcal PPE/PE had been vaccinated with pneumococcal vaccines. Thirty-nine of 76 (51.3%) had received a vaccine covering the serotype detected. Thirty of these 39 breakthrough cases were age-appropriately vaccinated with PCV13 and considered vaccine failures, including 26 children with serotype 3, three children with serotype 19A and one child with serotype 1.ConclusionFollowing the introduction of PCV13 in general childhood vaccination we observed a strong emergence of serotype 3 associated PPE/PE in the German pediatric population, including a considerable number of younger children with serotype 3 vaccine breakthrough cases and failures. Future PCVs should not only cover newly emerging serotypes, but also include a more effective component against serotype 3. 相似文献
37.
38.
Interstitial cystitis/bladder pain syndrome (IC/BPS) and vulvodynia are chronic pain syndromes that appear to be intertwined from the perspectives of embryology, pathology and epidemiology. These associations may account for similar responses to various therapies. 相似文献
39.
This retrospective study aimed to evaluate radiation-induced pneumonitis (RIP) and a related condition that we define in this report—prolonged minimal RIP (pmRIP)—after stereotactic body radiotherapy (SBRT) for Stage I primary lung cancer in patients with chronic obstructive pulmonary disease (COPD). We assessed 136 Stage I lung cancer patients with COPD who underwent SBRT. Airflow limitation on spirometry was classified into four Global Initiative for Chronic Obstructive Lung Disease (GOLD) grades, with minor modifications: GOLD 1 (mild), GOLD 2 (moderate), GOLD 3 (severe) and GOLD 4 (very severe). On this basis, we defined two subgroups: COPD-free (COPD −) and COPD-positive (COPD +). There was no significant difference in overall survival or cause-specific–survival between these groups. Of the 136 patients, 44 (32%) had pmRIP. Multivariate analysis showed that COPD and the Brinkman index were statistically significant risk factors for the development of pmRIP. COPD and the Brinkman index were predictive factors for pmRIP, although our findings also indicate that SBRT can be tolerated in early lung cancer patients with COPD. 相似文献
40.