Granulomatous mastitis secondary to histoplasmosis: report of a case diagnosed by fine-needle aspiration biopsy

A case of unilateral histoplasmal "granulomatous" mastitis diagnosed by fine-needle aspiration biopsy (FNAB) is presented. The clinical presentation and mammographic findings were strongly suspicious for carcinoma. FNAB cytology showed a picture of necrotizing granuloma secondary to histoplasmosis. The lesion was treated with surgical excision and appropriate antifungal therapy. The differential diagnosis of granulomatous mastitis is discussed.     

Internal maxillary artery ligation for idiopathic intractable epistaxis

Epistaxis though common, is rarely life threatening. Routinely nose pinching, anterior find posterior nasal packing and endoscopic cauterization of bleeding points is sufficient to control epistaxis in 99% of the cases. It is mandatory to rule out local and systemic causes before labeling a case as idiopathic by using a battery of investigative modalities. Here are two interesting cases of epistaxis which did not respond to conventional therapeutic modalities in which transantral internal maxillary artery ligation was attempted leading to complete cure.     

青霉素高产菌株的推理选育

目的：筛选一株优良的抗生素产生菌。方法：通过人为诱变来动摇产生菌原有的严密控制机制。结果：得到一种抗生素生物合成能力异常的突变株。结论：此方法可过量合成人们所期望的抗生素。     

对10种抗真菌药物的耐药监测及分析

目的 监测分析l0种抗真菌药物的耐药现状，以加强抗真菌药物的合理应用。方法 对我院2001年4月～2002年12月分离鉴定出的359株真菌．用目前常用的l0种抗真菌药物进行药物敏感试验和分析。结果 在l0种抗真菌药物中，耐药率最高的是灰黄霉素(耐药率87．3％～100％)，其次为氟康唑(42．8％-54．9%)和伊曲康唑(28．5％～50．9％)。结论 当前临床常用抗真菌药物的耐药菌株明显增多，特别是氟康唑、伊曲康唑耐药率增高，敏感率降低，应引起广大临床医生的高度重视。     

The soil fungusChaetomium in the human paranasal sinuses

Chaetomium is a soil fungus of which more than 180 species are now known. Most species cause degradation of cellulose-rich substrates, such as components in soil, straw or wood. Growth ofChaetomium globosum is often stimulated in the presence ofAspergillus fumigatus, which excretes such compounds as sugar phosphates and phospho-glyceric acid. A 73-year-old woman, with longstanding pain and secretion from her left maxillary sinus, was admitted to hospital where an infundibulectomy was performed. Histological examination showed necrotic material with hyphae ofA. fumigatus and perithecia ofChaetomium sp. The latter fungus is rarely pathogenic to man.     

Clinical Classification as a Guide to Treatment of Sinusitis in Children

Evaluation of all 153 children undergoing CT scan of the paranasal sinuses for recalcitrant sinusitis symptoms between January 1988 and July 1992 was performed. Clinical categorization into groups of patients presenting with chronic sinusitis (CS) and recurrent acute sinusitis (RAS) was based upon pattern of disease and presentation. Clinical symptoms and signs, radiological examination, treatment, and outcome were compared between these distinct clinical groups. Eighty-two (55%) children were categorized as RAS and 68 (45%) as CS. Children with CS presented more frequently with a persistent cough, purulent nasal discharge, immune deficiency, and more severe mucosal disease on CT than children with RAS. Medical therapy successfully controlled the symptoms of sinusitis in 79 (96%) with RAS versus 27 (40%) with CS. Surgery was performed in 44 children: 3 (3.6%) with RAS versus 41 (60%) with CS, p<0.01. At a mean follow-up of 2.0 years, >80% of all the children were either asymptomatic or improved regardless of treatment modality. These data support the use of clinical classification as a guide to medical versus surgical therapy in children with sinusitis.     

Rhinosinusite chronique de l''enfant: évolution des concepts

The concept of chronic rhinosinusitis in children has been recently individualized. The diagnosis is based upon the clinical history. It may be part of a diffuse inflammatory disease of the respiratory tract. Allergic and environmental polluting factors are possibly involved and must be looked for. Drainage of the rhinopharynx and local steroids are usually the first line treatment. In case of failure, a CT-scan of the sinuses should be performed looking for an obstructive anomaly of the sinuses requiring functional endoscopic sinus surgery     

58例上颌窦癌的临床疗效分析

目的　探讨上颌窦癌的诊断和治疗方法。方法　对 5 8例上颌窦癌患者在不同治疗情况下 ,包括手术、放疗、化疗 ,单纯或综合治疗下的生存情况进行回顾性分析。结果　单纯放疗或手术的 3年生存率均为 3 3 3 3 % ,5年生存率均为 16 67% ;综合治疗的 3年及 5年生存率分别为 75 %及 5 5 %。结论　早期诊断是提高上颌窦癌病人生存率的关键 ,以手术为主的综合治疗是最好的治疗方案     

我院院内真菌感染调查分析

目的预防和减少院内真菌感染。方法查阅我院2002年10月～2004年9月发生院内真菌感染患者的病历并进行分析。结果在107例院内真菌感染者中,60a以上者占72%;好发于呼吸道(81.3%)、消化道(14.0%)、泌尿道(10.3%),主要病原菌为白色念珠菌(92.5%);感染者均有大量应用广谱抗菌药物史,部分患者应用过肾上腺皮质激素类药物。结论合理应用广谱抗菌药物及肾上腺皮质激素类药物是预防院内真菌感染的重要手段。     

精析B超轨迹球

本文深入透彻的分析了常用轨迹球的基本构成和工作原理,设计了替换电路,并针对经常出现的故障给出了解决方法,而且就B超轨迹球的未来发展做出了展望.