首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1513篇
  免费   37篇
  国内免费   19篇
耳鼻咽喉   8篇
儿科学   23篇
基础医学   183篇
口腔科学   59篇
临床医学   140篇
内科学   17篇
皮肤病学   2篇
神经病学   48篇
特种医学   27篇
外科学   457篇
综合类   285篇
预防医学   62篇
眼科学   92篇
药学   113篇
中国医学   40篇
肿瘤学   13篇
  2024年   4篇
  2023年   29篇
  2022年   27篇
  2021年   47篇
  2020年   28篇
  2019年   25篇
  2018年   32篇
  2017年   33篇
  2016年   51篇
  2015年   49篇
  2014年   108篇
  2013年   98篇
  2012年   114篇
  2011年   145篇
  2010年   81篇
  2009年   89篇
  2008年   65篇
  2007年   57篇
  2006年   68篇
  2005年   61篇
  2004年   47篇
  2003年   56篇
  2002年   35篇
  2001年   31篇
  2000年   17篇
  1999年   21篇
  1998年   20篇
  1997年   11篇
  1996年   9篇
  1995年   13篇
  1994年   9篇
  1993年   3篇
  1992年   11篇
  1991年   5篇
  1990年   6篇
  1989年   2篇
  1988年   6篇
  1987年   4篇
  1986年   9篇
  1985年   8篇
  1984年   2篇
  1983年   3篇
  1982年   5篇
  1981年   3篇
  1980年   2篇
  1979年   3篇
  1977年   4篇
  1974年   4篇
  1973年   2篇
  1970年   3篇
排序方式: 共有1569条查询结果,搜索用时 27 毫秒
81.

Objectives

Iatrogenic injury of the Profunda Femoris Artery (PFA) at time of hip fixation surgery can increase morbidity and mortality and prolong the hospital stay. This is an injury that tends to pass unnoticed as a cause of postoperative deterioration despite being frequently reported in the literature. Our study aims to describe the anatomy of the PFA in relation to the medial femoral cortex with specific emphasis on its orientation relative to the position of a sliding hip screw side plate construct. By doing so we are able to present clear guidance to orthopaedic surgeons on how to avoid iatrogenic PFA injury at the time of hip fracture fixation.

Methods

Using Computed Tomography Angiographic (CTA) studies, the course of the PFA in relation to the medial femoral cortex was traced in 44 patients (28 males and 16 females) with mean age of 65.6 years. Coronal and axial CT sections were cross-linked to specify the position of the PFA at 1?cm intervals.

Results

The course of the artery could be divided into three parts relative to a fixed reference point. Proximal and distal parts of the artery were in a safer position in comparison to the middle part of the artery that was found very close to the femoral cortex and along the coronal axis of the femur (mean angle 2.9° from the femoral coronal axis and 13.8?mm from the medial femoral cortex). Using the commercially available side plate constructs, this part of the artery corresponded to the distal part of the plate (third and fourth holes).

Conclusion

Special attention needs to be practiced by the operating surgeon while drilling into the third and fourth holes of the side plate.  相似文献   
82.

Background

The number of screws used for sliding calcaneal osteotomy fixation has not been examined in the literature. The purpose of this paper is to examine this topic.

Methods

Retrospective chart review was performed on 190 patients who met selection criteria. We compared complication risk for single versus double screw, headed versus headless screw, and short versus longitudinal incision cases.

Results

The mean age was 48.4 (18–83) years and average follow up was 28 (12–150) weeks. All cases achieved radiographic union. Overall complication rate was 19.5% (37/190). Risk of complication did not differ significantly between single and double screw (RR: 1.170; 95% CI: 0.66–2.09; p = 0.594) or short and extended incision groups (RR: 0.868; 95% CI: 0.42–1.80; p = 0.704). Risk of complication differed significantly between headed and headless screw fixation (RR: 5.558; 95% CI: 2.69–11.50; p < 0.0001).

Conclusions

Single screw fixation of sliding calcaneal osteotomy achieves similar outcomes as double screw fixation. Headless screws are advantageous for minimizing hardware pain and subsequent hardware removal.  相似文献   
83.

Objective

The aim of this study was to describe an alternative fixation method for distal humeral extra-articular fractures through posterior approach using distal tibia anatomic locking plate; and to evaluate the patient's functional outcome and union condition.

Methods

Eighteen patients (11 men and 7 women; average age of 37.0 ± 17.3 years (range: 18–73 years)) with a distal humeral extra-articular fracture who were treated with distal tibial medial locking plate were included into the study. The mean follow up time was 36.2 ± 16.7 (12–57) months. Functional results were evaluated with perception of pain, range of joint motion, grasp and pinch strengths.

Results

Union was achieved in 17 of 18 patients. Only one patient had non-union due to infection and underwent debridement. The mean time for union was 7.8 ± 5.9 months (2–20). Patient perception of pain was X = 1.88 ± 2.50 and X = 4.55 ± 2.68, respectively, at rest and activity. The active ranges of joint motion were adequate for functional use. General functional state of affected extremity (DASH-T) was perfect (X = 27.14 ± 25.66), the performance of elbow joint was good (X = 84.44 ± 11.57). There were no differences in the comparison of grasp and pinch grip of patients with uninvolved extremity (p > 0.05).

Conclusions

In distal humeral extra-articular fractures, use of distal medial tibia plate has advantages such as providing high rates for union, low rates for complication, and early return to work with early rehabilitation, therefore it may be considered a fixation choice that can be used for distal humeral extra-articular fractures.

Level of evidence

Level IV, therapeutic study.  相似文献   
84.

Background Context

Fusion typically consists of joint preparation, grafting, and rigid fixation. Fusion has been successfully used to treat symptomatic disruptions of the sacroiliac joint (SIJ) and degenerative sacroiliitis using purpose-specific, threaded implants. The biomechanical performance of these systems is important but has not been studied.

Purpose

The objective of this study was to compare two techniques for placing primary (12.5?mm) and secondary (8.5?mm) implants across the SIJ.

Study Design

This is a human cadaveric biomechanical study of SIJ fixation.

Materials and Methods

Pure-moment testing was performed on 14 human SIJs in flexion-extension (FE), lateral bending (LB), and axial rotation (AR) with motion measured across the SIJ. Specimens were tested intact, after destabilization (cutting the pubic symphysis), after decortication and implantation of a primary 12.5-mm implant at S1 plus an 8.5-mm secondary implant at either S1 (S1–S1, n=8) or S2 (S1–S2, n=8), after cyclic loading, and after removal of the secondary implant. Ranges of motion (ROMs) were calculated for each test. Bone density was assessed on computed tomography and correlated with age and ROM. This study was funded by Zyga Technology but was run at an independent biomechanics laboratory.

Results

The mean±standard deviation intact ROM was 3.0±1.6° in FE, 1.5±1.0° in LB, and 2.0±1.0° in AR. Destabilization significantly increased the ROM by a mean 60%–150%. Implantation, in turn, significantly decreased ROM by 65%–71%, below the intact ROM. Cyclic loading did not impact ROM. Removing the secondary implant increased ROM by 46%–88% (non-significant). There was no difference between S1–S1 and S1–S2 constructs. Bone density was inversely correlated with age (R=0.69) and ROM (R=0.36–0.58).

Conclusions

Fixation with two threaded rods significantly reduces SIJ motion even in the presence of joint preparation and after initial loading. The location of the secondary 8.5-mm implant does not affect construct performance. Low bone density significantly affects fixation and should be considered when planning fusion constructs. Findings should be interpreted in the context of ongoing clinical studies.  相似文献   
85.
We developed a new fixation device for reconstruction of the anterior cruciate ligament with a multistrand hamstring graft. This device allows the graft tension to be readjusted after fixation. This device, called a Ligament Tension Screw, consists of three parts, a screw, a washer, and a post. To create the graft, the tendons were formed into a loop. The device was hung from one end of the loop of the graft and a Kennedy-ligament augmentation device (LAD) artificial ligament was hung at the other end. The Kennedy-LAD artificial ligament was used extraarticularly for fixation at the tibia with double staples. Graft tension was increased by turning the screw, which pulls on the post suspending the graft. Fifty-two patients were evaluated after a minimum 2-year follow-up. The evaluation included physical examination, stability measurement with a KT2000 arthrometer, a Cybex muscle strength measurement, a functional test, and scoring of the knee according to the International Knee Documentation Committee (IKDC). Pivot test was negative in 47 patients (91%), but glide occurred in 5 patients (9%). No patient had a "clunk" or markedly poor result on the pivot test. All patients recovered full extension. Seven patients lost full flexion, but the loss of flexion was less than 5° in all seven. The KT 2000 arthrometer measurement with 133 N anterior drawer force indicated that 46 patients (88%) had less than 3-mm side-to-side difference. The mean muscle strength of the quadriceps and hamstrings was 91% and 94%, respectively, compared with the findings in the contralateral limb. The functional test showed a one-leg hop distance equal to 94% of that the opposite side. According to the final IKDC evaluation, 48 patients were graded as normal or nearly normal, and 4 patients as abnormal; none was severely abnormal. This study demonstrated satisfactory results for the reconstruction with a multistrand hamstring graft fixed with the new Ligament Tension Screw. Received: February 15, 2001 / Accepted: July 30, 2001  相似文献   
86.
Summary The suppression of vestibular nystagmus (VN) by fixation of a small visual target moving with the observer was tested while subjects seated on a rotatable chair were oscillated at 0.1 Hz and peak accelerations of +-10 to 130°/s2. Total amplitudes of nystagmus during movement towards one direction occurring despite intended fixation were compared to slow phases of optokinetic nystagmus (OKN) and smooth pursuit (SP) towards the opposite direction.Supported by the Deutsche Forschungsgemeinschaft, SFB 70 (Hirnforschung und Sinnesphysiologie)  相似文献   
87.
C M Schor 《Vision research》1979,19(7):757-765
Small errors of fusional vergence (fixation disparity) were examined as a function of the magnitude of horizontal prism stimulating convergence or divergence for a short (30sec) duration. Marked differences were observed between the amplitude of fixation disparity resulting from convergent and divergent stimulus disparities. In another experiment, subjects wore a horizontal prism for 30 sec after which time one eye was occluded for 40 sec. Measurements of vergence eye movements revealed an incomplete relaxation of fusional vergence (prism adaptation) after 40 sec of occlusion. Marked differences were observed between the amplitude of prism adaptation resulting from convergent and divergent stimuli. Maximum prism adaptationand minimum fixation disparity occurred with the same direction of prism, suggesting that a slow fusional vergence mechanism minimizes errors of binocular vergence.  相似文献   
88.
Two experiments were conducted to investigate the roles of dark vergence and retinal eccentricity as factors influencing binocular vergence responses. A nonius alignment technique was used to measure vergence responses in total darkness (dark vergence) and for dim binocular stimuli presented at retinal eccentricities ranging from 2° to 8° over distances ranging from 28.5 to 342cm. The results indicate that vergence was progressively less accurate with stimuli at increasing retinal eccentricities and that errors of fixation were biased toward the individual's dark vergence position. The hypothesis that dark vergence represents the functional resting state of the vergence system which influences oculomotor fusional responses under a variety of conditions is discussed.  相似文献   
89.
90.
Abadi RV  Gowen E 《Vision research》2004,44(23):2675-2690
Primary fixation is never perfectly stable, but is frequently interrupted by slow drifts, microsaccades and saccadic intrusions (SI). SI are involuntary, conjugate movements which take the form of an initial fast movement away from the desired eye position and followed after a short duration, by either a return secondary saccade or a drift. The purpose of this study was to examine the prevalence and metrics of SI in a population of 50 healthy subjects. Using both one and two dimensional recordings we find that all 50 members of the subject group exhibited SI. The SI were bilateral, conjugate and horizontal. No purely vertical SI were detected when examined in three subjects. SI amplitude mean and range was 0.6° ± 0.5°, 0.1°-4.1°; SI frequency mean and range was 18.0 ± 14.3 per min, 1.0-54.8 per min; SI duration mean and range was 225 ± 150, 20-870 ms. The mean SI amplitude and frequency when SI < 0.5° were removed was 0.97° ± 0.56° and 7.0 ± 11.4 per min respectively. Age was positively correlated with SI amplitude (p < 0.01), but there was no correlation between age and SI frequency. Three of four types of SI monophasic square wave intrusions (MSWI), biphasic square wave intrusions (BSWI) and double saccadic pulses (DSP) were found to be exclusively saccadic, whilst the fourth type, the single saccadic pulses (SSP), were confirmed to exhibit a slow secondary component. MSWI were the most frequently observed SI occurring in 47 out of 50 (94%) of the subjects with a mean amplitude, frequency and duration of 0.7° ± 0.5°, 11.5 ± 11.6 per min, and 255 ± 147 ms respectively. Mean amplitudes and frequencies for BSWI (n = 20), SSP (n = 11) and DSP (n = 34) were found to be 0.50° ± 0.2°, 1.2 ± 2.5 per min; 0.40° ± 0.20°, 0.4 ± 1.0 per min and 0.3° ± 0.4°, 5.0 ± 8.7 per min respectively. No differences in MSWI characteristics were found between binocular and monocular viewing. Possible explanations for SI occurrence include experimental viewing conditions, subject fatigue and covert shifts in attention.  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号