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[目的] 研究中医综合疗法对青少年假性近视患者黄斑处脉络膜厚度及微血流密度的影响,为中医疗法在青少年假性近视的治疗方面提供依据。[方法] 使用SPSS 21.0软件产生随机数字,将51例(102只眼)假性近视青少年患者随机分成对照组和治疗组。对照组患者27例(54只眼),单纯使用复方托吡卡胺滴眼液点眼治疗;治疗组患者24例(48只眼),在对照组治疗的基础上配合中药雾化、中药眼贴和耳穴埋籽等中医综合治疗。两组患者疗程均为8周,治疗前后检测两组患者裸眼远视力、电脑验光屈光度数、黄斑中心凹下脉络膜厚度及黄斑区浅层血流密度,并评价两组患者疗效。[结果] 1)治疗组1例因中药雾化过敏导致脱落,最终纳入23例(46只眼)。2)治疗8周后,治疗组总有效率为92.3%,对照组总有效率为75.0%,治疗组疗效优于对照组,差异有统计学意义(P<0.05)。3)治疗后,治疗组患者平均视力较治疗前提高,差异具有统计学意义(P<0.05);对照组患者平均视力较治疗前无明显改善,差异无统计学意义(P>0.05)。组间比较方面,治疗组治疗后平均视力较对照组有一定提高,差异有统计学意义(P<0.05)。4)经治疗,治疗组患者平均假性近视度数较治疗前下降,差异有统计学意义(P<0.05);对照组患者平均假性近视度数较治疗前略有下降,差异无统计学意义(P>0.05)。组间比较方面,治疗组治疗后平均假性近视度数较对照组有一定下降,差异有统计学意义(P<0.05)。5)治疗组患者黄斑中心凹下脉络膜厚度较治疗前增厚,差异有统计学意义(P<0.05);对照组黄斑中心凹下脉络膜厚度较治疗前无明显改变,差异无统计学意义(P>0.05);组间比较方面,治疗组治疗后黄斑中心凹下脉络膜厚度较对照组增厚,两组比较差异有统计学意义(P<0.05)。6)治疗后,治疗组黄斑区浅层血流密度较治疗前增加,差异有统计学意义(P<0.05);对照组黄斑区浅层血流密度较治疗前增加,但差异无统计学意义(P>0.05);组间比较方面,治疗组治疗后黄斑区浅层血流密度较对照组明显增加,两组比较差异有统计学意义(P<0.05)。[结论] 采用中医综合疗法对青少年假性近视治疗效果较好,并且可以增加黄斑中心凹下脉络膜厚度及黄斑区浅层血流密度,短期观察无不良反应,值得临床推广运用。 相似文献
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The detailed morphology of neurons in the optic tectum of the common goldfish, Carassius auratus, was reinvestigated using rapid Golgi and Golgi-Cox methods. Neurons were classified initially on the basis of the orientation of the primary dendritic processes within the tectum: vertical, horizontal and non-oriented. These 3 groups were subdivided according to the shape of the soma and the axonal and dendritic configurations.The cell types observed in the present study were compared with those reported in earlier analyses of the goldfish optic tectum. Numerous differences, primarily of soma location and axonal origin and pathway for each cell type, were found. The structure of the goldfish optic tectum appears to be quite similar to the tectum of other teleosts. 相似文献
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Satoru Honma Akinari Tokiyoshi Katsushi Kawai Masahiro Koizumi Kodo Kodama 《Anatomical science international / Japanese Association of Anatomists》2008,83(4):232-238
A radial artery running beneath the biceps tendon was found in the cadaver of a Japanese woman during a student dissection
course at Kumamoto University School of Medicine in 2006. The brachial artery bifurcated into the radial artery and the ulnar
artery in the cubital fossa, and the radial artery twisted laterally running beneath the biceps tendon, and when it was situated
laterally to the tendon, twisted distally at the level of the radial tuberosity, and then twisted medially again. After the
radial artery passed over the biceps tendon, it turned distally and continued as a normal radial artery. The superficial brachial
artery, which coexisted with the brachial artery, was given off from the axillary artery and it continued to the final twist
of the radial artery. The course of this radial artery is similar to the arterial rings surrounding the biceps tendon, found
during the same dissection course. The arterial rings were formed between the brachial artery and the radial artery, and their
proximal origins ran beneath the biceps tendon, while the distal origins were superficial. The present arterial variation
is thought to have occurred when the normal part of the radial artery in the cubital fossa was substituted by the arterial
ring, coexisting with the superficial brachial artery, which usually disappears during normal development. Furthermore, it
is suggested that a part of the arterial ring always remains as a radial recurrent artery. 相似文献
16.
Bezabih M 《Diagnostic cytopathology》2004,31(5):347-351
The aim of this study was to describe the distributions of superficial malignant neoplasms diagnosed by fine-needle aspiration cytology (FNAC). A prospective cross-sectional study was conducted within the Jimma Teaching Hospital, Pathology Department, Jimma University during the years between September 1998 and August 2002. Cases fulfilling cytopathological evidences of superficial malignancies were included whereas deep-seated malignancies were excluded from the study. An air-dried smear stained with the Wright staining procedure was utilized for the FNAC diagnostic technique. A total of 3,200 cases were investigated during the study period where 267 (8.3%) cases were of primary superficial malignant neoplasms, with 98 cases in the peak age group of 40-59 yr (36.7%) and a median age of 38.0 yr (range, 0.2-88 yr). The most frequent superficial cytodiagnosis was breast carcinoma, 79 (29.6%) cases; followed by non-Hodgkin's lymphomas, 37 (13.9%) cases; and soft tissue sarcomas, 26 (9.7%) cases. The overall male-to-female ratio showed preponderance to female patients (1:1.3). Carcinomas were identified more frequently in those >40 yr of age whereas sarcomas were identified in those <40 yr of age (P > 0.05). The most common malignant neoplasm in women was breast carcinomas found in 74 (27.7%) cases, whereas in men non-Hodgkin's lymphomas were found in 29 (10.9%) cases. Large proportions of carcinomas (88 cases, 33.0%), lymphomas (33 cases, 12.4%), and sarcomas (20 cases, 7.5%) were detected on the trunk, head, and neck, as well as on the lower limb regions, respectively. This study uncovered different types of superficial malignant neoplasms that are prevalent in the southwestern part of Ethiopia. The most common types of cytodiagnoses such as breast carcinomas, etc. may suggest that attention be given to future high-caliber prospective studies in trying to identify some of the associated strong risk factors for the disease under study. This study may be helpful to local health planners in prioritizing some of the commonest malignancies. Some of the diagnostic challenges of lymphomas and thyroid follicular lesions were shown also. This investigation is the first in Ethiopia and therefore may act as baseline data for similar studies in the future. 相似文献
17.
小腿前外侧筋膜皮瓣的显微外科解剖学 总被引:1,自引:0,他引:1
在30例成人下肢标本上,观察了小腿前外侧筋膜皮瓣的血供。该部皮瓣血供来自腓浅动脉。该动脉在外踝尖上平均25.7±0.55cm处发自胫前动脉,与同名静脉、神经伴行,穿前外侧肌间隔浅出,沿小腿前外侧面下降,沿途向两侧发许多细小皮支,分别与小腿前,后皮动脉吻合,在深筋膜表面形成丰富的血管网。本文讨论了小腿前外侧筋膜皮瓣的应用解剖学要点。 相似文献
18.
Specialized neuroglial arrangement may explain the capacity of vomeronasal axons to reinnervate central neurons 总被引:8,自引:0,他引:8
G Raisman 《Neuroscience》1985,14(1):237-254
The neurosensory cells of the primary olfactory and vomeronasal projections are in a state of continuous replacement throughout adult life. Since their axons form synaptic terminals with neurons in the olfactory and accessory olfactory bulbs, this system is an apparent exception to the rule that peripheral axons cannot grow into the central nervous system of adult mammals. Electron microscopy of sections (especially in a plane tangential to the surface of the accessory olfactory bulb) shows a unique glial arrangement. By virtue of their greater electron density and "secretory-type" organelle content (Golgi apparatus and dense-core vesicles) the glial cells of the superficial layers of the accessory olfactory bulb are distinguished both from the glia of the vomeronasal nerves and from the astrocytes of the deeper bulbar layers. The synapses between the vomeronasal axons and the postsynaptic elements are formed in glomeruli which are encapsulated by an inner layer of glial cytoplasm derived from the superficial glia, and an outer layer derived from the astrocytes. The principle of the organization is that the superficial glial processes are reflected off the axons before they reach the synaptic terminal zone. Conversely, for the postsynaptic elements, the astrocytic processes are reflected off the dendrites of the accessory olfactory bulb neurons before they enter the core of the glomeruli. In effect, the synapses are formed in a "no-man's-land" between the two glial cell types. This peculiar glial arrangement may be important for the unique regenerative capacity of this system. 相似文献
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目的 基于网络药理学整合体内实验方法探究脉络舒通丸抗血栓性浅静脉炎(superficial thrombophlebitis,STP)的作用机制。方法 借助网络药理学方法,从药物及疾病相关数据库筛选脉络舒通丸的成分作用靶点及STP疾病相关靶点,根据拓扑特征值筛选关键靶点后,进行基因本体(gene ontology,GO)功能及京都基因与基因组百科全书(Kyoto encyclopedia of genes and genomes,KEGG)通路富集分析。将日本大耳白兔随机分为对照组、模型组、地奥司明(0.168 g/kg)组和脉络舒通丸低、中、高剂量(0.56、1.68、5.04 g/kg)组。除对照组外,其余各组均采用耳缘iv 20%甘露醇建立STP兔模型。造模同时各给药组连续ig给药14 d。采用苏木素-伊红(HE)染色法检测各组兔耳组织病理变化;ELISA检测各组血清中白细胞介素-1β(interleukin-1β,IL-1β)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和IL-6水平;Western blotting检测耳组织蛋白激酶B(pr... 相似文献