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51.
Summary Effects of STA-MCA anastomosis on two patients with neovascular glaucoma due to occlusion of the internal carotid artery are presented. Both patients improved in visual acuity and central retinal artery pressure as well as in signs of transient ischaemic attack. Postoperative angiography showed a marked decrease in collateral flow through the ophthalmic artery, which is reversed from the normal direction, with the development of blood flow through the anastomosis. Discussion is offered indicating that the lack of collateral flow through both the anterior and posterior communicating arteries is important in addition to occlusion of the internal carotid artery in order to produce full-blown ischaemic oculopathy such as venous stasis retinopathy, neovascular glaucoma or rubeosis iridis. It is stressed that EC-IC bypass surgery should be performed soon after the appearance of ischaemia and before the development of neovascular glaucoma or rubeosis iridis in order to obtain normal vision. In ischaemic oculopathy the results of EC-IC bypass can be evaluated objectively and quantitatively by many noninvasive neuro-ophthalmological tests which are important in discussing the efficacy of the bypass surgery. 相似文献
52.
A prospective hearing survey was performed in a sample of 102 diabetic patients. The hearing data were compared with the hearing thresholds of three control population groups. A significant difference was found in the average hearing thresholds between the diabetic patients and all of the three control populations. Diabetic patients have worse hearing threshold levels especially at low and mid frequencies (P < 0.001). There was also a correlation between the duration of diabetes and hearing loss. No significant correlation was found between the different stages of diabetic retinopathy and the degree of hearing loss. 相似文献
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55.
G. RAYMAN S. A. WILLIAMS J. GAMBLE J. E. TOOKE 《European journal of clinical investigation》1994,24(12):830-836
Abstract. The effect of lowering the foot on the factors governing fluid filtration in the foot were studied in 12 male insulin-dependent diabetic subjects and 10 controls. Toe skin blood flow, measured by laser Doppler flowmetry, was significantly higher during dependency in the diabetic group. In the control subjects, the colloid osmotic pressure of venous blood sampled from the foot rose to 47·7 mmHg (range 45·1–53·8) after 50 min of foot dependency. In the diabetic group, colloid osmotic pressure failed to rise to the same extent (median 36·7 mmHg; range 28·6–43·0; P < 0·001). Capillary pressure, measured directly by the Landis microinjection technique, was significantly higher in the diabetic group (85·3±1·7 ( n = 6) vs. 92·2±4·6 cm H2 O ( n = 6); P < 0·007), as was foot swelling rate determined by mercury strain gauge plethysmography (0·069±0·022 vs. 0·099±0·025 ml min-1 100ml-1 ; P < 0·02). These results suggest an impairment of the oedema-preventing mechanisms in diabetic subjects which may contribute to the risks of ulceration in the diabetic foot. 相似文献
56.
Summary This study describes reduced motor nerve conduction velocity and increased resistance to hypoxia-induced conduction failure in sciatic nerves of rats after four weeks of streptozotocin-induced diabetes (both effects were significant at p <0.05). These changes occurred in the absence of any deficit in the steady-state ouabain-sensitive adenosine triphosphatase (ATPase) activity of sciatic nerve endoneurial homogenates. The addition of 10 nmol/l insulin to endoneurial homogenates from control animals resulted in a 34% increase in ouabain-sensitive ATPase activity and a 19% reduction in ouabain-insensitive ATPase activity (both p <0.01). This stimulation of ouabain-sensitive ATPase activity by insulin did not occur in homogenates from diabetic rats. Treating diabetic rats daily with the aldose reductase inhibitor, imirestat (1 mg/kg) improved nerve conduction velocity (p <0.05) but was without effect upon the resistance to hypoxic conduction blockade or the deficit in insulin-stimulated oubain-sensitive ATPase activity. These data suggest that in streptozotocin-diabetic rats the functional disorders of reduced motor nerve conduction velocity and increased resistance to hypoxic conduction blockade do not share a common aetiology and that impaired nerve conduction is not related to reduced maximal potential oubain-sensitive ATPase activity. 相似文献
57.
胰激肽原酶治疗糖尿病足38例疗效分析 总被引:3,自引:0,他引:3
目的 观察胰激肽原酶改善微循环干预治疗糖尿病足的疗效。方法 选择38例确诊为糖尿病足的患者,结合下肢血管多普勒超声显像、肌电图、血液流变学检测,确定疗效。结果 胰激肽原酶治疗后,肢体影色多普勒超声显像显示下肢血管血流明显加快(P<0.01);神经电生理异常均有不同程度改善;血液粘度明显下降(P<0.01);足部症状明显缓解。结论 胰激肽原酶是一种干预糖尿病足进展的有效药物。 相似文献
58.
59.
Shuji Seki MD 《Surgery today》1987,17(2):123-129
The ratio of PaO2 to FiO2 was often low (300 or less) in four patients with complications of hyperosmolar hyperglycemic non-ketotic diabetic coma (HHNKDC)
following open heart surgery. Four of our patients had poor oxygenation and subsequent spontaneous recovery from in the immediate
post-operative period, although HHNKDC occurred only in one during this period. In the 3 others, poor oxygenation without
accompanying HHNKDC lasted for 1–6 days and HHNKDC developed about 2 weeks after open heart surgery at time when poor oxygenation
reoccurred. If a working diagnosis of congestive heart failure was made only on the basis of the most common probability,
and the fluid supply was restricted, HHNKDC would readily occur or be aggravated by the dehydration iatrogenically produced.
It is thus concluded that HHNKDC should be included in diagnoses for pulmonary dysfunction. 相似文献
60.
David M. Cockburn 《Clinical & experimental optometry》1987,70(5):156-165
The clinical characteristics of 100 consecutively presenting diabetic patients of an optometrist were investigated. This sample was drawn from 3798 patient first visits and represented 2.6% of the practice population sample. Diabetic retinopathy was present in 26% of the diabetic patients; this prevalence is similar to that found in diabetics examined in community based surveys. The ocular complications of diabetics observed in this study appeared to be similar to those of diabetics in the general community. The mean random blood glucose levels of the diabetics having retinopathy was not significantly different from those not having retinopathy. A first degree family history of diabetes was admitted by 46% of the diabetic subjects and was the most common associated clinical feature surveyed; a control group of non-diabetic subjects had a first degree family history of diabetes in 10% of cases. In seven patients, the diabetes was diagnosed as a result of signs detected at the optometric examination; these signs are listed. No newly diagnosed diabetic had diabetic retinopathy as a presenting sign. Ocular and systemic signs, other than diabetic retinopathy, were sought and a high prevalence of cardiovascular disease was detected in these diabetic patients. The vision of the diabetic patients was compared to that of 100 randomly selected age and sex matched controls; there was no significant difference in the visual acuity of the two groups. The implications of this finding are discussed. Guidelines for the detection and management of diabetic patients of optometrists are suggested. 相似文献