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991.
The present paper reports 11 cases of light chain disease (LCD) sequently found in several citles over Fujian province, Immunological classification of this group of LCD ww as follows: six of me cases belonged to type λ, four of them were type κ, and another one was a double LCD. We found that LCD was common in Fujlan only next to multiple myeloma (MM) of IgG class and accounted for 20% of the total 55 MM cases found in recent yean.It to well known that In matt patients of LCD M protein or Bence Jones proteinemia (BJPemia) to not detectable by conventional electro-phoresis. Our studies show that by making serum protein along with urinary BJP electrophoresis on the same one gel plate the sltuation can be greatly Improved It not only favour* the recognition of smail and faint band or bands of free light chain in serum, but also provides a repid and sensitive way, i. e. , immunofixation, to directly detect urinary light chain on the gel plate Immediately after electrophresis has been run. 相似文献
992.
ROSS W SHEPHERD 《Journal of gastroenterology and hepatology》1996,11(5):S7-S10
Orthotopic liver transplantation (OLT) is now a definitive treatment option for most cases of endstage liver disease (ESLD) in children. Efforts now focus on active supportive treatment to maintain, if not improve, the patient's clinical status before OLT and to ensure normal patterns of growth and development after OLT. Malnutrition adversely affects the outcome of OLT and is probably the single area in pre-operative management where the largest potential improvement can be made. Our studies indicate significant abnormalities of protein energy metabolism and body composition in children referred for OLT. We have shown that the use of enteral formulae, enriched with branched-chain amino acids, have significant advantages. Other adjunctive therapy, such as growth hormone, is the subject of current investigation. Following transplantation, catch-up weight and growth does occur with the advent of normal liver functioning, but patients at continuing risk for undernutrition, such as those with rejection and/or chronic infection, need to be targeted for specific nutritional therapy. 相似文献
993.
994.
Attitudes of College Football Officials Regarding NCAA Mouthguard Regulations and Player Compliance 总被引:1,自引:0,他引:1
Dennis N. Ranalli DDS MDS Diana M. Lancaster PhD 《Journal of public health dentistry》1993,53(2):96-100
The National Collegiate Athletic Association (NCAA) mandates the use of brightly colored, intraoral mouth- guards by football players to reduce the frequency and severity of craniofacial and intraoral morbidity and mortality, and to enhance the ability of officials to observe player compliance. The purpose of this 12-question mail survey was to determine the attitudes of on-Held game officials regarding current NCAA mouthguard regulations and patterns of utilization by college football players. The sample consisted of all 50 Big East Football Conference officials; a response rate of 100 percent was achieved. Only 42 percent of the officials reported observing all players in compliance, and quarterbacks were identified by others as the least compliant group (52%). The majority (88%) indicated that the 1990 rule for brightly colored mouthguards had been beneficial to them in determining player compliance, and 52 percent reported that this rule had resulted in more frequent use by these athletes. Nearly all officials (96%) indicated that they would issue a warning for noncompliance to the player or coach, rather than charging a timeout for a violation as prescribed by NCAA regulations. The majority (70%) believe current enforcement is appropriate, but expressed the opinion that coaches should be held more accountable for player compliance. 相似文献
995.
Forty-one cases of chondrosarcoma from varying sites throughout the body, and treated exclusively by one of the authors (R. L. H.) from 1972 to 1990 were reviewed. The symptoms, signs, location of tumours, treatment and progress are presented. Particular attention was paid to modular bone replacement techniques. Excision and reconstruction of the bone or joint were carried out in 17 femora, five tibia and six humeri. Comparison between this method of management and other techniques is discussed. Titanium and alumina prostheses for the hip, femur, tibia, shoulder and humerus have been designed by the senior author. These are both inert and modular, and have been found to be superior to other methods of treatment in both function and cosmesis. They do not possess the same potential donor infection risks and other disadvantages of allograft replacement. Immediate postoperative weight bearing and mobilization are possible with these systems. The Huckstep prostheses allow for bony in growth into their porous coated alumina sleeves, spacers and stems. In addition, the titanium alloy locking component for the femoral stems has an elasticity half that of other metal alloys and this was found to minimize stress shielding. 相似文献
996.
目的 建立一种特异、敏感、简捷的PCR检测食蟹猴疟原虫(P.C)的方法。方法 检测样品来自人工接种感染P.C的阳性猴血膜及滤纸血斑。根据P.C SSUrRNA基因序列,设计P.C特异引物Pc1和Pc3,用PCR常规操作对P.C DNA模板扩增。同时用多对间日疟原虫(P.V)特异引物对照比较。结果 从 P.C血样中扩增出 425bp特定扩增带,而P.V红内期和子孢子、恶性疟原虫、伯氏疟原虫、人基因组DNA和健康猴血均未见扩增带;敏感度可检测 1.68 ×10-6的原虫感染水平。同时发现P.C对多对 P.V特异引物均出现阳性扩增带,以往一直未被注意。结论 该方法检测 P.C特异、敏感和简捷,提供了鉴别 P.V与 P.C的准确诊断。建议在 PCR的P.V引物设计和特异性的检测过程,把应用P.C DNA检测列为常规对照,以提高检测质量。 相似文献
997.
Beat Morell Manuel Meyer Othmar Porr Ulrich Bay Ernst R. Froesch 《Acta diabetologica》1984,21(4):303-313
Summary The objective of this study was to follow the development of microalbuminuria and nerve conduction velocity under continuous
i.v. insulin therapy over a limited period of 4 months. For this purpose, 8 labile type I diabetics were selected (age 33±8
years, duration of diabetes 16±9 years) and treated conventionally with two insulin injections daily over 4 months. Afterwards,
the same patients were treated with continuous i.v. insulin infusion and finally again with two injections daily over 4 months
each. This procedure allowed each diabetic to serve as his own control. HbA1, microalbuminuria, nerve conduction velocity and relative refractory period of the ulnar nerve were checked at montly intervals.
During the continuous i.v. infusion over 4 months, blood sugar values were significantly lower, glucosuria had disappeared
almost completely and the glycosylated hemoglobin had fallen to near normal values. The mean rate of albumin excretion was
16±5 μg/min at rest and 76±26 μg/min during exercise (normal: 3.9±0.4 and 4.8±1.2 μg/min, respectively) and did not change
significantly. Nerve conduction velocity in the ulnar nerve rose significantly under i.v. insulin therapy from 47.9±0.6 m/sec
to 52±0.6 m/sec. Similarly, the relative refractory period of the same nerve fell significantly from 3.7±0.2 to 1.9±0.1 msec
(i.e. to within normal range). It is concluded that functional disturbances of peripheral nerve can regress by improved blood
sugar control with continuous i.v. insulin infusion over 4 months. On the other hand, incipient microangiopathy measured as
microalbuminuria remains unchanged over the same period of time. If an improvement is at all possible, considerably longer
periods of euglycemia are likely to be necessary.
Supported by Grant No. 3.964-0.80 from the Swiss National Science Foundation. 相似文献
998.
目的:研究不同种类和强度基牙材料与瓷冠破折碎裂的内在关系.方法:选用计算机建立上颌中切牙的三维有限元模型,模拟陶瓷层、牙本质、核桩等结构.分析在天然齿基牙、钴铬合金基牙及复合树脂基牙情况下,铸造玻璃陶瓷全冠的瓷层内及残余牙本质的应力分布情况.结果:高弹性模量的钴铬合金能够降低瓷层及残余牙本质内的最大主应力和最小主应力峰值,防止瓷层破折碎裂;而弹性模量与牙本质相近的复合树脂桩降低应力峰值的作用不明显.结论:对于有牙髓活力的牙本质基牙,尽量保存牙髓活力后行全冠修复.对于行根管治疗术后的无髓牙,进行核桩冠修复时,采用高弹性模量的高熔合金,尽量避免使用弹性模量较小的复合树脂核. 相似文献
999.
Rosario Ceballo Jennifer E. Lansford Antonia Abbey Abigail J. Stewart 《Family relations》2004,53(1):38-48
This study compares the experience of gaining a child through birth, adoption, or marriage, extending the focus of investigation beyond biological parenthood and the transition made by first‐time parents. Using a subsample from the National Survey of Families and Households (N = 204), we compared reasons for having children, parental well‐being, family relationships, and work roles among parents who gained a child biologically, through adoption, or by becoming a stepparent. Overall, there were many similarities in the impact of gaining a child across the three parental groups. Repeated measures analyses of covariance showed that across family groups, after gaining a child, respondents reported less depressed affect, more disagreements with their spouse, and more support from their own parents. The differences across groups suggest that the experience of becoming an adoptive parent or a stepparent may be less stressful than the adjustment to biological parenthood. 相似文献
1000.