温针灸治疗心脾两虚型慢性疲劳综合征50例疗效观察

目的：观察温针灸五脏背俞穴治疗心脾两虚型慢性疲劳综合征的临床疗效。方法：将100例心脾两虚型慢性疲劳综合征患者随机分为2组各50例，治疗组予温针灸五脏背俞穴治疗；对照组口服归脾丸治疗，比较2组临床疗效。结果：总有效率治疗组为96．0％，对照组为80．0％，2组临床疗效总有效率比较，差异有显著性意义（P〈0．05），治疗组疗效优于对照组。治疗组在体倦乏力、记忆力或注意力下降、劳累后持续不适、肌肉痛4项单项症状治疗的有效率分别与对照组比较，差异均有显著性意义（P〈0．05）。结论：温针灸五脏背俞穴治疗慢性疲劳综合征疗效良好。     

Follow-up of patients with retroperitoneal sarcoma

Retroperitoneal sarcomas (RPS) are rare malignancies that are potentially curable by complete surgical resection. A regular surveillance program is normally commenced following surgery due to the risk of local recurrence (LR), especially in low-intermediate grade disease, and distant metastases (DM), especially in high-grade RPS. Consensus guidelines usually advocate for more frequent imaging during the first 2–3 years and less intensive imaging over a prolonged period thereafter, reflecting the incidence pattern of LR and DM. Definitive evidence for the most effective imaging schedule has never been provided, and retrospective studies have not shown an association between follow-up intensity and survival. Improvement in the prediction of recurrence patterns has been sustained by prognostic dynamic nomograms, which are now capable of forecasting disease behaviour in each patient according to specific features. Incorporation of such tools in clinical practice may help to stratify patients and tailor ongoing surveillance to the risk of recurrence. This may help to relieve patients’ anxiety while awaiting results of surveillance investigations, and also reduce the economic and environmental burden of repeated imaging. A randomized controlled study (SARveillance Trial) is proposed to shed light on this controversial topic, allowing clinicians to harmonize the follow-up protocol of patients undergoing surgery for RPS.     

膝骨关节炎中医辨证分型与中医体质类型关联性分析

目的:调查膝骨关节炎人群中医体质类型及中医证型分布情况,初探膝骨关节炎中医证型与中医体质的关联性。方法:收集188例膝骨关节炎患者为观察组,100例非膝骨关节炎为对照组,逐一判定中医体质类型及中医证型,统计中医体质及中医证型的分布情况,并采用Logistic回归分析,探讨膝骨关节炎与中医体质类型、中医证型与中医体质类型的关联性。结果:①观察组偏颇质以阳虚质、气虚质、阴虚质最常见;②阳虚质、气虚质、阴虚质为膝骨关节炎正向风险因素;③观察组症候表现复杂,以肝肾亏虚证为主,其次为寒湿痹阻证、气血虚弱证、气滞血瘀证;④中医证型与中医体质类型相关联,其中寒湿痹阻证与气虚质显著相关;肝肾亏虚证与阳虚质、气虚质、阴虚质显著相关;气血虚弱证与阳虚质、气虚质、阴虚质显著相关;气滞血瘀证与阳虚质显著相关。结论:阳虚质、气虚质、阴虚质人群易患膝骨关节炎;膝骨关节炎人群以肝肾亏虚证居多,寒湿痹阻证次之,气血虚弱证和气滞血瘀证较少;从不同体质与中医证型的关系来看,寒湿痹阻证与气虚质显著相关;肝肾亏虚证与阳虚质、气虚质、阴虚质显著相关;气血虚弱证与阳虚质、气虚质、阴虚质显著相关;气滞血瘀证与阳虚质显著相关。     

肝性脑病与血管性痴呆的文献证素比较研究

目的:总结肝性脑病中医证素特点,并与血管性痴呆比较,突出该病病机特点,为今后研究肝性脑病和轻微型肝性脑病提供借鉴。方法:按照检索策略检出符合纳入标准和排除标准的文献,提取证候和证素信息,总结肝性脑病中医证素特点,并与血管性痴呆研究结果进行比较。结果:1)肝性脑病以热毒内陷心包、痰蒙清窍、痰热腑实,腑气不通、阴阳俱脱、湿热蒙窍、瘀阻清窍、肝风内动、气阴两竭、痰火扰心、肝脾失调等证型多见,其中实证较多。2)肝性脑病组火热、湿、毒等实邪扰动心神,风邪内动所致比例明显高于血管性痴呆组,而阴虚、血瘀、气虚比例明显低于血管性痴呆组,湿、风、疫毒为肝性脑病组特有。结论:肝性脑病病位以心、肝为主,病性以实邪为多,兼有虚实夹杂。实以火热、痰、毒扰动清窍为主,虚以阴虚、气虚为主。