全文获取类型
收费全文 | 4644篇 |
免费 | 134篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 84篇 |
儿科学 | 102篇 |
妇产科学 | 74篇 |
基础医学 | 845篇 |
口腔科学 | 63篇 |
临床医学 | 838篇 |
内科学 | 201篇 |
皮肤病学 | 15篇 |
神经病学 | 271篇 |
特种医学 | 116篇 |
外科学 | 706篇 |
综合类 | 517篇 |
预防医学 | 520篇 |
眼科学 | 20篇 |
药学 | 170篇 |
1篇 | |
中国医学 | 162篇 |
肿瘤学 | 101篇 |
出版年
2023年 | 69篇 |
2022年 | 187篇 |
2021年 | 240篇 |
2020年 | 210篇 |
2019年 | 273篇 |
2018年 | 293篇 |
2017年 | 222篇 |
2016年 | 157篇 |
2015年 | 125篇 |
2014年 | 387篇 |
2013年 | 387篇 |
2012年 | 226篇 |
2011年 | 304篇 |
2010年 | 259篇 |
2009年 | 210篇 |
2008年 | 242篇 |
2007年 | 160篇 |
2006年 | 121篇 |
2005年 | 126篇 |
2004年 | 83篇 |
2003年 | 87篇 |
2002年 | 46篇 |
2001年 | 57篇 |
2000年 | 28篇 |
1999年 | 20篇 |
1998年 | 26篇 |
1997年 | 18篇 |
1996年 | 15篇 |
1995年 | 15篇 |
1994年 | 16篇 |
1993年 | 9篇 |
1992年 | 14篇 |
1991年 | 5篇 |
1990年 | 8篇 |
1989年 | 8篇 |
1987年 | 8篇 |
1986年 | 8篇 |
1985年 | 13篇 |
1984年 | 11篇 |
1982年 | 10篇 |
1981年 | 7篇 |
1980年 | 13篇 |
1979年 | 9篇 |
1978年 | 12篇 |
1977年 | 8篇 |
1975年 | 5篇 |
1974年 | 9篇 |
1973年 | 9篇 |
1972年 | 5篇 |
1971年 | 5篇 |
排序方式: 共有4806条查询结果,搜索用时 15 毫秒
11.
Sérgio Carreir?o Leandro Pereira Marcelo Wilson Rocha Almeida 《Aesthetic plastic surgery》2009,33(3):445-451
Surgical procedures for the mammary region currently are assuming an important role in body-contouring surgery. Enhancement
of results is a constant challenge to the plastic surgeon. A simple and efficient maneuver for resection of the breast’s lateral
pole based on the mammoplasty technique of Professor Ivo Pitanguy is described.
This study realized at the Private Clinic Sérgio Carreir?o, Rio de Janeiro, RJ, Brazil. 相似文献
12.
Priti Bandi M.S. Vilma E. Cokkinides Ph.D. J. Lee Westmaas Ph.D. Elizabeth Ward Ph.D. 《The Journal of adolescent health》2008,43(6):612-615
There is limited information on the relationship between parental practices that specifically discourage current cigarette smoking and adolescent cessation, and how this relationship varies by age. Among 1629 adolescent smokers, self-reported receipt of parental communication not to smoke was significantly and positively associated with readiness to quit. The strength and significance of this association decreased from early to middle adolescence and was not significant in late adolescence. 相似文献
13.
Alessio Pigazzi Minia Hellan Douglas R. Ewing Benjamin I. Paz Garth H. Ballantyne 《Journal of gastrointestinal surgery》2007,11(6):778-782
Laparoscopic colectomy is a difficult procedure with a long learning curve. We describe in this study our technique for right-
and left-sided laparoscopic medial-to-lateral colectomy. The medial approach involves division of the vascular pedicle first,
followed by mobilization of the mesentery toward the abdominal wall, and finally freeing of the colon along the white line
of Toldt. This approach allows immediate identification of the plane between the mesocolon and the retroperitoneum and renders
the dissection fast and safe. Our series of 50 consecutive laparoscopic colectomies supports this concept. We believe that
surgeons familiar with this technique will have an important tool in their armamentarium to circumvent some of the challenges
of laparoscopic colectomy. 相似文献
14.
Daniel A. Monti Marie E. Stoner Gail Zivin Martha Schlesinger 《Journal of cancer survivorship》2007,1(2):161-166
Introduction As many as one quarter of all cancer survivors report traumatic stress symptoms from cancer-related experiences. While the
majority of these patients do not meet the criteria for posttraumatic stress disorder (PTSD), there is growing evidence that
subsyndromal symptoms can significantly contribute to functional impairment and negative health outcomes. Treatment options
for the hallmark symptoms of traumatic stress—unpleasant, intrusive thoughts and avoidant behaviors—have not been well investigated
for the cancer survivorship population.
Materials and methods Seven female cancer survivors with traumatic stress symptoms from cancer-related experiences and no other major psychopathology,
were enrolled to receive three sessions of Neuro-Emotional Technique (NET), a brief, targeted treatment that combines traditional
desensitization principles with complementary modalities.
Results Psychological outcome measures (Impact of Event Scale (IES) and Subjective Units of Distress (SUD) and physiological measures
(Heart Rate (HR) and Skin Conductance Level (SCL) demonstrated the following changes: 71% on IES, 88% SUD, 74% on HR, and
65% on SCL following the intervention. Statistically significant changes were observed for all four parameters, and effect
size g for proportion improved were 0.50 each for IES, SUD, and HR, and 0.20 for SCL.
Conclusions These cases suggest feasibility of the NET intervention for cancer-related traumatic stress and the potential for change in
symptoms and physiological reactivity. Further investigation is needed to determine the specific and long-term effects of
such an approach.
Implications for cancer survivors Traumatic stress from cancer-related experiences might represent a constellation of symptoms that are amenable to brief, targeted
interventions.
This study was supported by the O.N.E. Research Foundation 相似文献
15.
急性缺氧对大鼠海马神经元钙激活钾通道的作用 总被引:1,自引:0,他引:1
目的:本实验采用膜片钳单通道技术研究缺氧条件下对培养新生大鼠海马神经元钙激活钾通道的作用;方法:取1 ~3天的SD大鼠海马神经元组织,制成细胞悬液,加入含80 %DMEM(dulbecco' s modified eagle' s medium)、20 %小牛血清培养基进行培养,将培养3 ~5天的形态典型的神经元置于对称性高钾溶液中,用膜钳技术记录单通道电流,其通道电流通过膜片钳放大器(CEZ -2200)放大,滤波(3KHz)后,经A/D、D/A转换器输入计算机,采用pClamp6 .0 .6软件采样分析;结果:在细胞贴附式下,应用氰化钠(20μmol/L)造成细胞急性缺氧,在缺氧早期(5 ~20 min)通道开放概率增加(P<0 .01或P<0 .05 ,n=5) ,而缺氧后期(20 ~30 min) ,通道开放概率明显降低,表明缺氧时间对通道的开放概率有明显影响。结论:缺氧早期神经元钙激活钾通道有自身激活作用,当钙激活钾通道激活时,钾离子外流增加,产生膜的复极化,使去极化不易产生,从而稳定细胞膜及降低细胞的兴奋性,这可能是缺氧早期神经元自身的一种代偿机制。 相似文献
16.
通过实验的方法来研究结晶过程中各种参数对氨苄西林晶型的影响来考察混合时对氨苄西林溶液结晶过程的影响,选择最佳的结晶工艺条件,更好地指导生产实践过程。经过实验考察,获得最佳的结晶工艺,使产品的各项质量指标提高,认为是氨苄西林的最佳结晶工艺。 相似文献
17.
One of the advantages of polyurethane foam-covered prostheses has been that in the first 5 to 10 years after their use, the
amount of capsular contraction was found much less than when similar ``slick' prostheses were used. Another advance was their
fixation to the surrounding tissue thus giving a more natural appearance and movement with the muscles when the arms were
moved in any direction. The formation of a thick capsule also acted as a protection against gel granuloma due to rupture of
the prosthesis and has been thought to be a factor in the lower capsule contraction rate. The greatest disadvantage has been
that its removal was extremely difficult and this has continued up until the technique described in this paper has been introduced. 相似文献
18.
W. G. Selley FDS Hon FCST R. E. Ellis MPhil F. C. Flack PhD C. R. Bayliss MB B Chir FRCR V. R. Pearce MB FRCP 《Dysphagia》1994,9(3):162-167
Simultaneous recording of adult subjects sipping small amounts of fluid from a cup have been obtained by videofluoroscopy together with feeding respiratory patterns and swallow sounds from the Exeter Dysphagia Assessment Technique (EDAT). These allowed visual representations of respiration and swallow sounds to be superimposed on a videofluoroscopy recording using a split-screen technique. Sequentially numbered, 1/50 sec, half-frame photographic prints were examined and schematic drawings of the relevant radiographs were made. These were superimposed on to the actual EDAT printed chart of the same swallow event, theri exact time relationship with respiration and cervical swallow sounds being preserved. The results allow events in the barium videofluoroscopy to be related to events in the feeding respiratory pattern and swallow sounds recorded by EDAT. 相似文献
19.
Mainly incited by the bushfirelike spread of endoscopic operative techniques in general surgery, thoracoscopy has become the object of new interest in the field of thoracic surgery. Location and resection of lung tumors are problematic for several reasons and so far not standardized. The main problems are pointed out. A new technique together with the instruments and their advantages is demonstrated. Future aspects are discussed. 相似文献
20.
Rita Noumeir 《Journal of digital imaging》2006,19(4):295-306
Recently, the digital imaging and communications in medicine (DICOM) standard introduced rules for the encoding, transmission,
and storage of the imaging diagnostic report. This medical document can be stored and communicated with the images in picture
archiving and communication system (PACS). It is a structured document that contains text with links to other data such as
images, waveforms, and spatial or temporal coordinates. Its structure, along with its wide use of coded information, enables
the semantic understanding of the data that is essential for the Electronic Healthcare Record deployment. In this article,
we present DICOM Structured Report (SR) and discuss its benefits. We show how SR enables efficient radiology workflow, improves
patient care, optimizes reimbursement, and enhances the radiology ergonomic working conditions. As structured input significantly
alters the interpretation process, understanding all its benefits is necessary to support the change.
Biography Rita Noumeir is a professor at the Department of Electrical Engineering of the University of Quebec, école de Technologie Superieure in
Montreal. A founding member of the Imaging, Vision, and Artificial Intelligence Laboratory (LIVIA), her main research interest
is the Healthcare Information Technology, specifically, Interoperability, Electronic Patient Record, Security, Information
Confidentiality, and Image Processing.
As a member of both Technical and Planning International IHE Radiology Committees, Dr. Noumeir took part over the last 5 years
in developing many Integrating the Healthcare Enterprise (IHE) Integration Profiles in Radiology and in organizing several
Integration Demonstrations. She is a cofounder of IHE Canada.
Dr. Noumeir contributed to many research and development projects in collaboration with several Canadian and international
companies in medical imaging and healthcare information. Currently, she collaborates with the Diagnostic Imaging Team of Canada
Health Infoway to define the principles and architecture for sharing imaging information between multiple healthcare institutions.
She plays a leading role in the development of this solution that is published as an IHE Integration Profile for which she
is the editor.
Rita Noumeir holds a Ph.D. and a Masters degree in Biomedical Engineering from école Polytechnique of Montreal specializing
in Medical Imaging. She is a professional engineer, and a member of the Ordre des ingénieurs du Québec. 相似文献