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61.
Magnetic resonance imaging (MRI) provides several advantages over computed tomography (CT) in the evaluation of head and neck region tumors. The improved soft-tissue contrast among normal and abnormal tissues provided by MRI now permits the exact delineation of tumor margins in the nasopharynx, oropharynx, and skull base regions. In addition, the ability to depict cross-sectional anatomy and pathology in three planes without intravenous contrast, patient manipulation, or ionizing irradiation is a distinct advantage of MRI over CT scanning. Drawbacks of MRI include the detection of subtle osseous abnormalities, patient motion, and artifacts introduced by ferromagnetic dental appliances. These drawbacks appear minimal when compared to the benefits of improved soft-tissue contrast and the ability to image exact tumor volumes.  相似文献   
62.

Introduction and objectives

Chemoradiotherapy is the treatment of choice for nasopharyngeal carcinoma. Local recurrences are one of the leading causes of death in these patients, and surgical salvage the treatment of choice. Our goal was to evaluate and compare the results of salvage surgery in the treatment of local recurrence of nasopharyngeal carcinomas comparing endoscopic to open approaches.

Methods

Twenty patients with local recurrence of nasopharyngeal carcinomas underwent surgery: 12 patients underwent open surgery and 8 endoscopic endonasal transpterygoid nasopharyngectomy. One patient was classified as rT1; 3 as rT2;2 as rT3; and 6 as rT4 in the group of open approaches; in the endoscopic series, 2 patients were rT1, 5 rT2 and one rT3.

Results

In 3 patients (25%) operated by an open approach (one rT4, one rT3 and one rT2) a complete gross resection was not achieved. Gross total resection was achieved in patients operated by endoscopic surgery. The complication rate in the group operated by an open approach was 92% (5 minor complications, 5 moderate complications, and one serious complication) and in the group that underwent endoscopic surgery all patients had some complication (7 had minor complications and one patient developed a severe complication). Survival at 3 and 5 years was 53% and 42% with the open approach and 100% and 50% with the endoscopic approach, respectively.

Conclusions

Endoscopic approaches decrease the morbidity associated with open approaches and allow for favourable oncological control.  相似文献   
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64.
目的探讨鼻腔鼻咽部NK/T细胞淋巴瘤的CT表现特征。方法回顾性分析经手术病理证实的23例鼻腔鼻咽部NK/T细胞淋巴瘤的临床资料及CT表现。结果鼻腔病变为主者18例,均位于单侧鼻腔,位于鼻腔前部11例,后部4例,呈弥漫表现的3例;CT表现肿块呈密度均匀的软组织密度影,增强后轻至中度强化;其中11例鼻中隔受累,5例伴有鼻咽受侵,13例合并鼻旁窦窦腔透光度降低,9例鼻前庭皮肤受侵犯,8例相邻骨质侵蚀破坏。鼻咽部病变为主者5例,表现为鼻咽顶后壁及侧壁不均匀增厚的软组织密度影,2例内可见气泡影,表面不光滑,增强后轻至中度强化;咽旁间隙受侵3例,鼻后孔受侵2例。结论鼻腔鼻咽部NK/T细胞淋巴瘤的CT表现具有一定的特征性。  相似文献   
65.
We report the first case of an isolated choanal fungus ball in a 28-year-old man with a previous history of nasopharyngeal carcinoma, who was treated with radiotherapy 14 years ago. The initial diagnosis was a recurrent tumour or a secondary neoplasm. Histopathological examination confirmed a fungal infection. There are no previous reports of a fungus ball located at the posterior choanal region. Although it has been reported that bacteriology of sinonasal region would be different in irradiated patients, there is no study reporting fungal infections in irradiated patients in English literature.In this report, the clinical presentation, relevant radiologic findings and management of sinonasal fungus ball and its relationship with previous radiotherapy were discussed with the literature knowledge.  相似文献   
66.
Rhabdomyosarcoma is a highly invasive malignant tumour arising from the mesenchymal tissue. Here, we reported a rare case of embryonal rhadomyosarcoma of nasopharynx with extension to different spaces of base of skull and orbit. Rarity of the case difficulty in diagnosis encourages its reporting.  相似文献   
67.
The present case report is of a young female with complaint of foul smelling nasal discharge normal anterior rhinoscopic findings and an irregular mass on digital palpation of nasopharynx, confirmed by NCCT and extracted through oral route  相似文献   
68.
We present a case of non-keratinizing carcinoma of the nasopharynx (NK-NPC) with an unusual histopathological pattern. The neoplastic cells were arranged in anastomosing cords embedded in a stroma which contained a significant component of alcian blue-positive myxoid substance forming a reticular pattern. These histopathological features gave an initial impression of a salivary gland-type carcinoma. On immunohistochemistry the tumor cells were strongly and diffusely positive for cytokeratins (AE1-3 and 5/6) and p63 and there was strong and diffuse nuclear positivity for Epstein–Barr virus-encoded small RNA on in situ hybridization. This case highlights the histomorphological variability of NK-NPC. Awareness of the histological spectrum of NK-NPC is important in clinical practice and this is not always adequately highlighted in currently used standard textbooks of Head and Neck Pathology.  相似文献   
69.
70.
目的 探讨整体护理对预防鼻咽癌放射治疗患者口腔黏膜炎的应用效果.方法 将102例接受放射治疗的鼻咽癌患者随机分为对照组和干预组,每组51例,对照组采用常规护理,干预组采用整体护理,比较两组患者口腔黏膜炎的发生率及严重程度.结果 干预组口腔黏膜炎发生率明显低于对照组,严重程度较对照组轻,差异有统计学意义(x2 =4.15,P<0.05).结论 整体护理能降低鼻咽癌放射治疗患者口腔黏膜炎的发生率,减轻口腔黏膜炎严重程度,提高患者生存质量.  相似文献   
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