Association of late effects of single,severe traumatic brain injury with Alzheimer’s disease using amyloid PET

Traumatic brain injury (TBI) is suggested to be a risk factor for the onset of Alzheimer’s disease (AD); however, the data remain controversial. This is the first report on cognitive decline in patients with TBI over 30 years post-injury. The medical significance/key learning points of this report are that (1) Functional Independence Measure (FIM) is useful in clinical settings, such as for higher brain dysfunction and dementia; (2) amyloid PET findings represent an essential biomarker for follow-up after TBI; and (3) cognitive decline can occur in patients with TBI more than 30 years post-injury.     

Predicting Motor and Cognitive Improvement Through Machine Learning Algorithm in Human Subject that Underwent a Rehabilitation Treatment in the Early Stage of Stroke

Background

The objective of this study was to investigate, in subject with stroke, the exact role as prognostic factor of common inflammatory biomarkers and other markers in predicting motor and/or cognitive improvement after rehabilitation treatment from early stage of stroke.

The Need and Its Influence Factors for Community-based Rehabilitation Services for Disabled Persons in One District in Beijing

Purpose To explore the needs for basic community-based rehabilitation services for disabled persons in Xuanwu District, Beijing, China, and to identify factors which influence disabled persons to accept rehabilitation services. Method One hundred and eight disabled persons were selected by systematic sampling and simple random sampling to assess their needs for community-based rehabilitation services. Results Of the interviewees, 57A% needed the community-based rehabilitation services, but only 13.9% took advantage of it. The main factors influencing the interviewees to accept these services were cost （P〈0.05）, knowledge about rehabilitation medicine （P〈0.05）; and the belief in the therapeutic benefit of the community-based rehabilitation service （P〈0.05）. Conclusion A considerable gap exists between the supply of community-based rehabilitation services in Beijing and the needs for these services by disabled residents underscoring the need for improved availability, and for additional research.     

康复科住院患者功能独立性测量与住院费用和时间的关系

目的　探讨康复科神经伤病患者住院费用的特点、入院功能独立性测量 (FunctionalIndepen denceMeasure ,FIM )及其分量表分与住院费用和时间的关系。方法　回顾调查了 1994～ 1998年在康复科住院的记录完整的 64例神经伤病患者住院费用与FIM资料 ,并进行统计学分析。结果　住院患者人均住院时间为 98.77± 99.15d ;人均住院总费用为 2 2 5 79.61± 2 170 2 .2 4元 ;入院FIM、自我照料、括约肌控制、转移、运动分量表分与住院时间均呈负相关 (r =-0 .2 5 3～ -0 .3 14 ,P <0 .0 5 ) ,入院FIM与床位费、治疗费、西药费、总费用呈负相关 (r =-0 .2 77～ -0 .3 5 3 ;P <0 .0 1～ 0 .0 5 ) ;住院时间与和各项住院费用间均有较好的正相关 (r =0 .40 4～ 0 .82 7,P <0 .0 1)。在脑卒中、外伤性脑损害、脊髓损伤三个疾病组中 ,脑卒中组入院FIM分与住院时间、治疗费、总费用呈显著负相关 (r =-0 .3 81～ -0 .44 4,P <0 .0 5 ) ,三组住院时间与床位费、治疗费、西药费均呈良好正相关 (r =0 .5 40～ 0 .878,P <0 .0 1～ 0 .0 5 )。结论　在康复科住院患者费用中 ,西药费最高 ,其次为治疗费 ;各项住院费用随住院时间延长而增高 ;患者的住院费用与入院时残疾程度有关 ;入院FIM分、自我照料、括约肌控制、转移项和运动     

现代综合促进技术治疗急性脑卒中

对120例急性期脑卒中患者随机分为康复组及常规组各60例。康复组又按临床神经功能缺损程度积分分为轻、中、重3型。康复组及常现组均给以常规药物治疗，康复组同时配合以促进技术为主的综合运动疗法进行早期康复干预。采用FIM躯体功能评分及Fugl-Meyerr积分评估运动功能。结果显示：康复组患者两项指标均有显著改善，与常规组比较，差异明显P＜0．01．康复组中轻、中型预后好，轻型患者康复干预影响因素较少些，自然恢复比重大，中、重型之间疗效差异显著，中型患者康复效果最高，另外脑出血恢复优于脑梗塞。     

功能综合评定量表的信度与效度的初步研究

目的应用功能综合评定量表(FCA)和功能独立性测定量表(FIM)对脑卒中患者的功能测定结果进行比较研究,以测定FCA的信度和效度. 方法随机对20例脑卒中后遗症期患者进行FCA和FIM评定,主要内容包括运动功能和认知功能二大项,对10例脑卒中患者进行FCA的组内相关系数的研究. 结果FCA和FIM的比较研究得出t=0.0451,P>0.05,显示FCA与FIM评定结果无显著差别,相关系数r=0.997,P<0.001,呈极显著相关,表明FCA量表的效度较好,FCA的组内相关系数各单项平均为0.929(P<0.001),显示有很好的可重复性. 结论 FCA与FIM相比,同样有较好的效度,FCA也有较好的信度,可供临床医师选择.     

脑卒中病人FIM评估与护理工作相关性的研究

目的 考证功能独立评测（Funcitional Independence Measure，FIM）对脑卒中病人功能状态评定的有效性，同时探讨FIM对护理工作的预测作用。方法 根据FIM制定的考察项目将护理工作分6类，在病人入院后72h内和出院前1周进行打分．记录24h护理工作时间。结果 随着FIM对病人运动和认知功能评分的提高，病人——护士接触时间减少：给药、提供治疗、宣教所用的时间与FIM评分显著相关。结论 护理工作质量和FIM评分之间的相关性表明了FIM的有效性，通过FIM评分可以预测护理工作需求量。     

Evaluation of a German version of the Rivermead Mobility Index (RMI) in acute and chronic stroke patients

The English Rivermead Mobility Index (RMI) has been proposed as a simple, valid and reliable measure in stroke rehabilitation. A German version was established and validated in two centres. In centre A 46 acute (median: 3.0 days after onset) and in centre B 151 chronic (median: 88.0 days after onset) stroke patients participated. Interrater reliability of the German RMI was tested in 12 subjects in the acute stage of stroke and was found to be statistically significant (r = 0.98, P < 0.0001). In centre A, a statistically significant correlation was found between the German RMI and the 10-m walk time at baseline (r = 0.73, P < 0.0001) and after three weeks (r = 0.92, P < 0.0001). In centre B, the German RMI correlated significantly with the motor part of the Functional Independence Measure (motor-FIM) on admission (r = 0.78, P < 0.0001) and after three weeks (r = 0.79, P < 0.0001), respectively. The change of the RMI correlated significantly with the change in 10-m walk time in acute patients (r = 0.87, P < 0.0001) and with the change in motor-FIM in chronic patients (r = 0.54, P < 0.0001). A moderate ceiling-effect was detected in the chronic study population. The German RMI appears to be a reliable, valid and responsive measure for mobility disability in acute and chronic stroke patients.