一次性注射针头在老年人胸骨骨髓穿刺中的应用

目的 探讨应用一次性注射针头进行老年人胸骨骨髓穿刺的可行性。方法 应用一次性注射针头对38例老年患者进行胸骨骨髓穿刺。结果 共进行45次穿刺，一次性穿刺成功44次，一次性成功率97．8％，所有取材满意，无骨髓液稀释，无局部感染、出血、穿刺意外发生。结论 应用一次性注射针头进行老年人胸骨骨髓穿刺，具有方便、快捷、安全、损伤小、取材好等优点。     

中西医结合治疗细菌性肝脓肿临床观察

目的：观察抗生素、厌氧治疗、局部穿刺引流合用中药“银鱼角消脓汤”治疗细菌性肝脓肿的疗效。方法：对临床诊断细菌性肝脓肿患者66例随机分为两组。治疗组44例用中西医结合治疗，对照组22例用单纯西医治疗。观察两组总有效率及体温复常、疼痛消失、血象复常、脓肿消失、住院时间五项临床指标。结果：治疗组总有效率95．5％，明显高于对照组的77．3％（P〈0．05），临床五项指标治疗组均优于对照组。结论：中西医结合治疗细菌性肝脓肿比单纯西医治疗更有效。     

CLINICAL OBSERVATION ON THE TREATMENT OF CHRONIC FATIGUE SYNDROME WITH DEEPLY PUNCTURED ELONGATED NEEDLE COMBINED WITH COMPREHENSIVE NURSING

Chronicfatiguesyndrome(CFS)referstoa groupofclinicalsymptomsandsignsincludingmain symptom extremefatiguewithoutapparentreason,andconcurrentsymptomsandsignsaspoormemory,inabilitytoconcentrate,sorethroat,tendernessof thelymphnodesaroundtheneckorinthearmpitre gion,lowfever,headache,muscleandjointache,somnipathy,andnoticeablepost exertionalmalaise whicheitherhangonorcomeandgofrequentlyfor morethan6months.Inaddition,inpeoplewith CFS,physicalexaminationandroutinelabtestshow noanyabnormalfindings.I…     

脓毒症心肌损害新生大鼠模型的建立

【摘要】 目的 建立一种具有良好稳定性及重复性的能模拟新生儿脓毒症（NS）心肌损害的新生大鼠动物模型,为研究NS致病机制及防治提供模型动物。方法 选取出生10天的健康雄性SD新生大鼠54只,随机分为正常对照组、假手术组（Sham组）、盲肠结扎穿孔术组（CLP组）,每组各18只。通过观察血培养菌落生长,采用酶联免疫吸附法（ELISA）对血清肌钙蛋白I（cTNI）浓度、心肌组织肿瘤坏死因子α（TNF α）和白细胞介素1β（IL 1β）含量进行检测,光镜下观察HE染色后心肌组织的病理变化。结果 正常对照组和Sham组新生大鼠的血培养结果均为阴性,CLP组新生大鼠的血培养中检出以大肠杆菌为主的菌落。正常对照组新生大鼠的血清cTNI浓度、心肌组织TNF α和IL 1β含量和Sham组比较差异无统计学意义（P＞0.05）;CLP组新生大鼠的血清cTNI浓度、心肌组织TNF α和IL 1β含量较Sham组明显增加（P＜0.05）。正常对照组和Sham组的心肌组织HE染色示心肌细胞均未出现炎性改变,但CLP组心肌细胞周围出现了炎性细胞浸润等病理改变。结论 通过盲肠结扎穿孔可建立较为理想的脓毒症心肌损害新生大鼠模型。     

LEEP刀在中重度宫颈糜烂患者中的综合应用价值研究

目的：探讨LEEP刀在中重度宫颈糜烂患者中的综合应用价值。方法选取2012年1月～2013年12月本院收治的90例中重度宫颈糜烂患者为研究对象，将其随机分为对照组（微波治疗组）45例和观察组（LEEP刀组）45例，比较两组的治疗效果，统计两组治疗前后的宫颈局部微循环指标及血流变指标。结果观察组中重度宫颈糜烂患者的治疗总有效率均高于对照组，差异有统计学意义（P＜0.05）；观察组治疗后不同时间点的宫颈微循环状态及血流变指标均优于对照组，差异有统计学意义（P＜0.05）。结论 LEEP刀在中重度宫颈糜烂患者中的综合应用价值较高，可有效控制糜烂及宫颈局部微循环。     

高校教职工2型糖尿病59例临床分析

目的：探讨2型糖尿病（T2DM）患者的发病情况和综合治疗效果及影响因素。方法：对59例T2DM患者的一般情况、合并症、并发症、ECG表现以及临床综合治疗情况进行分析。结果：高校教职工T2DM患者年龄多为中老年，60岁以上占74．58％，且合并症多，其中合并高血压76．27％，高血脂57．63％，体重异常47．46％，眼病变33．90％，肾病变30．50％。结论：高校T2DM患者教职工T2DM多为中老年患者，绝大多数合并有“三高”及其它并发症，ECG改变明显，同时患者对糖尿病知识的掌握不全面。     

基于TOPSIS法和综合指数法的贵州省中药民族药企业可持续发展能力综合评价研究

目的:对贵州省中药民族药企业可持续发展能力进行评价,发现影响企业可持续发展能力的因素,进一步提升贵州省中药民族药企业可持续发展能力。方法:通过构建的指标体系,运用TOPSIS法和综合指数法对贵州省中药民族药企业可持续发展能力进行综合评价。结果:TOPSIS法排名前三位的企业依次为企业14、企业10和企业21,Ci值分别为0.9569,0.9533,0.9493,综合指数法排名前三位的企业分别为企业10、企业14和企业5,综合指数分别为0.6518、0.6516,0.5571。结论:TOPSIS法和综合指数法分析结果基本一致,说明TOPSIS法和综合指数法能够客观地反映贵州省中药民族药企业可持续发展能力大小,且目前影响贵州省中药民族药可持续发展能力提升的主要因素是研究开发能力、资源投入回报能力和市场营销能力,因此应采取吸引人才、重视创新、企业合理兼并、加大财政支持等相应措施,提升中药民族药企业可持续发展能力。     

The Tension and Puncture Properties of HDPE Geomembrane under the Corrosion of Leachate

To investigate the gradual failure of high-density polyethylene (HDPE) geomembrane as a result of long-term corrosion, four dynamic corrosion tests were conducted at different temperatures and durations. By combining tension and puncture tests, we systematically studied the variation law of tension and puncture properties of the HDPE geomembrane under different corrosion conditions. Results showed that tension and puncture failure of the HDPE geomembrane was progressive, and tensile strength in the longitudinal grain direction was evidently better than that in the transverse direction. Punctures appeared shortly after puncture force reached the puncture strength. The tensile strength of geomembrane was in inversely proportional to the corrosion time, and the impact of corrosion was more obvious in the longitudinal direction than transverse direction. As corrosion time increased, puncture strength decreased and corresponding deformation increased. As with corrosion time, the increase of corrosion temperature induced the decrease of geomembrane tensile strength. Tensile and puncture strength were extremely sensitive to temperature. Overall, residual strength had a negative correlation with corrosion time or temperature. Elongation variation increased initially and then decreased with the increase in temperature. However, it did not show significant law with corrosion time. The reduction in puncture strength and the increase in puncture deformation had positive correlations with corrosion time or temperature. The geomembrane softened under corrosion condition. The conclusion may be applicable to the proper designing of the HDPE geomembrane in landfill barrier system.     

Does post dural puncture headache exist in idiopathic intracranial hypertension? A pilot study

Background/ObjectiveOccurrence of post-dural puncture headache (PDPH) after diagnostic lumbar puncture (LP) for idiopathic intracranial hypertension (IIH) may seem very unlikely in clinical practice. Nevertheless, it has been suggested by several studies, mainly in sub-group analyses. We aimed to evaluate the prevalence of PDPH in an IIH population and determine any eventual predictive factors of PDPH occurrence.MethodsWe conducted a retrospective multiple-center observational study. All newly diagnosed IIH patients who met the International Classification of Headache Disorders (ICHD-3) or the Dandy modified criteria were included from three different French hospitals. They all underwent LP following the same process with the same type of needle. We recorded PDPH occurring within five days after LP, as defined by ICHD-3 criteria.ResultsSeventy-four IIH patients were recruited, of whom 23 (31%) presented with PDPH. Neither classical risk factors for PDPH such as body mass index, age or gender, nor cerebrospinal fluid opening pressure, or specific IIH features were associated with occurrence of PDPH.ConclusionPDPH can occur after LP in IIH patients. Clinicians should be aware of this possible event during the IIH diagnosis assessment and should not automatically reconsider IIH diagnosis. PDPH prevention using an atraumatic needle and dedicated PDPH treatment seem relevant in IIH patients.