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331.
Sabreen Waleed Ibrahim Aula Kamal Rafeeq Mustafa Sabah Ahmedhamdi 《Saudi Dental Journal》2021,33(8):1142-1148
BackgroundThe application of nanoscale surface modification was found to be useful in the improvement of osseointegration of endosseous dental implants. The fluorapatite (FA)/alumina (Al2O3) mixture is recognized for its outstanding bioinertia and can significantly increase the biocompatibility and bioactivity of biomaterials.ObjectiveThe aim of the present work was to evaluate the bone response to nano-alumina- and fluorapatite-coated dental implants using rabbit tibiae.Material and MethodsThe coating was performed using the dip-coating method. Commercially pure titanium screw-type implants were used as a control group. The coated implants were the experimental group. Each group consisted of 12 screws that were surgically implanted in 6 healthy New Zealand rabbits. Histological and histomorphometric evaluations were performed at the bone to implant contact (BIC) interface, bone fraction area occupancy (BAFO) and fibrous tissue at 2 and 6 weeks of healing.ResultsThis analysis showed that the coated implants had more rapid osseointegration than the control group, with a significant difference after 2 and 6 weeks of healing for both groups. The histomorphometric evaluation demonstrated higher values for BIC% and BAFO% and lower values of fibrous tissue in the mixture-coated Ti implants than in the control group.ConclusionThe current study suggested that the nano-alumina and fluorapatite mixture coating is a favourable candidate for rapid osseointegration over uncoated implants. 相似文献
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《Burns : journal of the International Society for Burn Injuries》2023,49(5):1052-1061
ObjectiveTranscutaneous osseointegration for amputees (TOFA) surgically implants a prosthetic anchor into the residual limb’s bone, enabling direct skeletal connection to a prosthetic limb and eliminating the socket. TOFA has demonstrated significant mobility and quality of life benefits for most amputees, but concerns regarding its safety for patients with burned skin have limited its use. This is the first report of the use of TOFA for burned amputees.MethodsRetrospective chart review was performed of five patients (eight limbs) with a history of burn trauma and subsequent osseointegration. The primary outcome was adverse events such as infection and additional surgery. Secondary outcomes included mobility and quality of life changes.ResultsThe five patients (eight limbs) had an average follow-up time of 3.8 ± 1.7 (range 2.1–6.6) years. We found no issues of skin compatibility or pain associated with the TOFA implant. Three patients underwent subsequent surgical debridement, one of whom had both implants removed and eventually reimplanted. K-level mobility improved (K2 +, 0/5 vs 4/5). Other mobility and quality of life outcomes comparisons are limited by available data.ConclusionTOFA is safe and compatible for amputees with a history of burn trauma. Rehabilitation capacity is influenced more by the patient’s overall medical and physical capacity than their specific burn injury. Judicious use of TOFA for appropriately selected burn amputees seems safe and merited. 相似文献
335.
目的 研究紫外线光功能化对二氧化纳米管钛表面改性钛种植体骨结合的影响。方法 采用预阳极氧化法制备二氧化钛(TiO2)纳米管表面改性钛种植体,并用波长为250 nm、功率为2mW/cm2紫外线(UVA)对种植体进行处理。将种植体植入SD大鼠股骨,12周后取含种植体骨组织制作组织切片,通过显微镜观察种植体周围骨组织形成情况并计算骨结合率。结果UVA处理组种植体周围新生骨组织多于未UVA处理组,且更致密。UVA处理组和未UVA处理组的骨结合率分别为(72.21±10.42)%和(44.98±9.62)%,两组之间的差异具有统计学意义(P<.05)。结论UVA光功能化TiO2纳米管表面改性有助于促进钛种植体骨结合。 相似文献
336.
TM种植体的表面特征与骨整合 总被引:9,自引:1,他引:8
目的 对TM种植体的阳佳表面特征进行研究。方法 选用3种不同表面特征的TM种植体,建立山羊下颌骨种种植模型。通过骨一种植体硬组织切片,观察了骨一种植体界面。结果 粗化处理有利于骨整合的发生,低结晶度的生物生陶瓷涂层更有利于骨整合,且便于倒楔形间隙的骨形成。结论 TM种植体的表面最好采用低结晶度的生物活性陶瓷涂层。 相似文献