全文获取类型
收费全文 | 10722篇 |
免费 | 1254篇 |
国内免费 | 212篇 |
专业分类
耳鼻咽喉 | 78篇 |
儿科学 | 190篇 |
妇产科学 | 61篇 |
基础医学 | 1333篇 |
口腔科学 | 1484篇 |
临床医学 | 784篇 |
内科学 | 1335篇 |
皮肤病学 | 123篇 |
神经病学 | 1637篇 |
特种医学 | 337篇 |
外科学 | 1004篇 |
综合类 | 1129篇 |
预防医学 | 778篇 |
眼科学 | 753篇 |
药学 | 681篇 |
15篇 | |
中国医学 | 209篇 |
肿瘤学 | 257篇 |
出版年
2024年 | 16篇 |
2023年 | 135篇 |
2022年 | 211篇 |
2021年 | 650篇 |
2020年 | 465篇 |
2019年 | 453篇 |
2018年 | 429篇 |
2017年 | 475篇 |
2016年 | 479篇 |
2015年 | 513篇 |
2014年 | 687篇 |
2013年 | 815篇 |
2012年 | 593篇 |
2011年 | 672篇 |
2010年 | 532篇 |
2009年 | 489篇 |
2008年 | 449篇 |
2007年 | 422篇 |
2006年 | 352篇 |
2005年 | 341篇 |
2004年 | 292篇 |
2003年 | 285篇 |
2002年 | 270篇 |
2001年 | 217篇 |
2000年 | 149篇 |
1999年 | 145篇 |
1998年 | 153篇 |
1997年 | 143篇 |
1996年 | 154篇 |
1995年 | 108篇 |
1994年 | 104篇 |
1993年 | 90篇 |
1992年 | 95篇 |
1991年 | 100篇 |
1990年 | 74篇 |
1989年 | 67篇 |
1988年 | 61篇 |
1987年 | 62篇 |
1986年 | 69篇 |
1985年 | 73篇 |
1984年 | 54篇 |
1983年 | 47篇 |
1982年 | 42篇 |
1981年 | 51篇 |
1980年 | 33篇 |
1979年 | 21篇 |
1978年 | 20篇 |
1976年 | 7篇 |
1975年 | 5篇 |
1973年 | 6篇 |
排序方式: 共有10000条查询结果,搜索用时 17 毫秒
11.
12.
13.
Altan Ahmed John A. Stauffer Jordan D. LeGout Justin Burns Kristopher Croome Ricardo Paz-Fumagalli Gregory Frey Beau Toskich 《Journal of gastrointestinal oncology.》2021,12(2):751
BackgroundNeoadjuvant yttrium-90 transarterial radioembolization (TARE) is increasingly being used as a strategy to facilitate resection of otherwise unresectable tumors due to its ability to generate both tumor response and remnant liver hypertrophy. Perioperative outcomes after the use of neoadjuvant lobar TARE remain underinvestigated.MethodsA single center retrospective review of patients who underwent lobar TARE prior to major hepatectomy for primary or metastatic liver cancer between 2007 and 2018 was conducted. Baseline demographics, radioembolization parameters, pre- and post-radioembolization volumetrics, intra-operative surgical data, adverse events, and post-operative outcomes were analyzed.ResultsTwenty-six patients underwent major hepatectomy after neoadjuvant lobar TARE. The mean age was 58.3 years (17–88 years). 62% of patients (n=16) had primary liver malignancies while the remainder had metastatic disease. Liver resection included right hepatectomy or trisegmentectomy, left or extended left hepatectomy, and sectorectomy/segmentectomy in 77% (n=20), 8% (n=2), and 15% (n=4) of patients, respectively. The mean length of stay was 8.3 days (range, 3–33 days) and there were no grade IV morbidities or 90-day mortalities. The incidence of post hepatectomy liver failure (PHLF) was 3.8% (n=1). The median time to progression after resection was 4.5 months (range, 3.3–10 months). Twenty-three percent (n=6) of patients had no recurrence. The median survival was 28.9 months (range, 16.9–46.8 months) from major hepatectomy and 37.6 months (range, 25.2–53.1 months) from TARE.ConclusionsMajor hepatectomy after neoadjuvant lobar radioembolization is safe with a low incidence of PHLF. 相似文献
14.
The aim of this study was to design a new intravenous blood–gas exchange device and to estimate the design characteristics
of the device with a dimensionless function by using a substance that can be used instead of bovine blood. In addition, the
characteristics of oxygen transfer were estimated using empirical formulas and the reliability of the equations was ascertained
by comparing their output with an experiment performed using bovine blood. The dimensionless function was derived using distilled
water and bovine blood to estimate the oxygen transfer rate. Using the derived equations, the calculated oxygen transfer rates
for bovine blood and distilled water were similar for Reynolds numbers ranging from 0.7 to 7.0. Therefore, it is possible
to estimate the oxygen transfer rate in bovine blood, which is a non-Newtonian fluid, using distilled water, which is a Newtonian
fluid. Moreover, it was possible to verify the related equations because the oxygen transfer rate could be estimated using
the derived equations, according to the diameters of the various device modules. 相似文献
15.
放射性肝纤维化过程的定量研究 总被引:6,自引:0,他引:6
经^60Coγ线照射大鼠肝区,通过光镜、电镜和图像分析仪、宣研究了照后1年肝脏的病理改变。结果表明,30Gy组在照射后1年内逐渐发生了放射性肝纤维化病变。在肝纤维化发生过程中,肝细胞内糖原颗凿含量进行性减少,间质中胶原纤维含量进行性增加,网状纤维于照射1-3个月呈进行性增加。 相似文献
16.
Xin Mei Jiang Akio Ohnishi Tatsunori Yamamoto Yoshiyuki Murai Akira Awaya Masato Ikeda 《Acta neuropathologica》1995,90(2):130-134
One of the pyrimidine compounds, 2-piperadino-6-methyl-5-oxo-5,6-dihydro(7H)pyrrolo[3,4-d]pyrimidine (MS-818), has neurotropic effects in vitro. Therefore, we studied the effect of MS-818 on the regeneration of the peroneal nerve in C57BL/6J mice after a crush injury. Two test groups, which received a daily intraperitoneal injection of 5 mg/kg or 10 mg/kg MS-818, respectively, were compared with controls, which received daily intraperitoneal injections of physiological saline, over a 14-day period. The maximum foot-width ratio (crushed side/uncrushed side) was obtained on days 1, 8 and 14 after the crush injury, and the various morphometric parameters were evaluated at both 5 and 10 mm distal to the proximal portion of the crush site. The significant effects of MS-818 included a larger maximum foot width (P<0.04) and a greater number of unmyelinated axons per nerve at both levels (P<0.003) in both test groups than in controls. MS-818 had no significant effects on body weight, the increase of total transverse fascicular area after the crush injury, the total number of myelinated fibers with their size distributions, or the number of nuclei of Schwann cells and macrophages. Therefore, we conclude that MS-818 promotes axonal sprouting and elongation after a crush injury in mice. 相似文献
17.
J. Saßmannshausen N. Bornfeld A. Kluge W. Sauerwein F. Härting A. Wessing 《International ophthalmology》1989,13(4):243-251
Advanced malignant melanomas of the uvea unsuited for an eye salvaging approach require enucleation of the tumor containing eye. A series of 68 patients is reported who underwent enucleation combined with insertion of a spherical dura-encased implant after 30 Gray pre-irridiation therapy of the orbit. Postoperative results with special attention to cosmetic outcome and motility of the prosthesis suggest that the insertion of an orbital implant should be preferred to the enucleation with no implant. 相似文献
18.
19.
目的 探讨彩超在肾移植术后并发肝脏恶性肿瘤监测中的应用价值。 方法 应用 Acuson12 8XP彩色多普勒超声诊断仪 ,对在我院行异体肾移植手术的终末期尿毒症患者 12 0 0例进行规律随访。 结果 发现 17例恶性肿瘤 ,其中肝癌 7例 ,占 4 1.17%。 5例肿块单发 ,2例多发 ;肿块最大 10 cm× 10 cm,最小 2 .3cm× 2 .1cm。其中 6例手术病理证实 ,1例肝活检证实。 结论 对移植肾术后患者 ,首选彩超随访肝脏变化 ,能早期发现肿瘤 ,为临床选择治疗方案提供时机 ,并提高换肾后发生恶性肿瘤患者的存活率 相似文献
20.