全文获取类型
收费全文 | 39887篇 |
免费 | 2682篇 |
国内免费 | 95篇 |
专业分类
耳鼻咽喉 | 122篇 |
儿科学 | 15332篇 |
妇产科学 | 1236篇 |
基础医学 | 4462篇 |
口腔科学 | 188篇 |
临床医学 | 1971篇 |
内科学 | 6449篇 |
皮肤病学 | 351篇 |
神经病学 | 2979篇 |
特种医学 | 416篇 |
外国民族医学 | 1篇 |
外科学 | 3085篇 |
综合类 | 1258篇 |
现状与发展 | 1篇 |
一般理论 | 18篇 |
预防医学 | 2983篇 |
眼科学 | 188篇 |
药学 | 949篇 |
4篇 | |
中国医学 | 58篇 |
肿瘤学 | 613篇 |
出版年
2023年 | 685篇 |
2022年 | 831篇 |
2021年 | 1106篇 |
2020年 | 1193篇 |
2019年 | 858篇 |
2018年 | 1175篇 |
2017年 | 1133篇 |
2016年 | 1152篇 |
2015年 | 1259篇 |
2014年 | 2000篇 |
2013年 | 1635篇 |
2012年 | 1433篇 |
2011年 | 1436篇 |
2010年 | 1477篇 |
2009年 | 1462篇 |
2008年 | 1271篇 |
2007年 | 1265篇 |
2006年 | 1203篇 |
2005年 | 1227篇 |
2004年 | 1128篇 |
2003年 | 1096篇 |
2002年 | 1061篇 |
2001年 | 1162篇 |
2000年 | 1107篇 |
1999年 | 1118篇 |
1998年 | 747篇 |
1997年 | 669篇 |
1996年 | 714篇 |
1995年 | 721篇 |
1994年 | 689篇 |
1993年 | 657篇 |
1992年 | 831篇 |
1991年 | 929篇 |
1990年 | 913篇 |
1989年 | 799篇 |
1988年 | 794篇 |
1987年 | 480篇 |
1986年 | 258篇 |
1985年 | 268篇 |
1984年 | 237篇 |
1983年 | 224篇 |
1982年 | 255篇 |
1981年 | 201篇 |
1980年 | 188篇 |
1979年 | 183篇 |
1978年 | 161篇 |
1977年 | 163篇 |
1975年 | 141篇 |
1974年 | 135篇 |
1973年 | 139篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
《Journal of diabetes and its complications》2022,36(7):108205
AimsWe examined the impact of memory complaints on the concordance between self-report (SR) and electronically monitored (EM) medication adherence, independent of depression symptoms, among adults with type 2 diabetes (T2D).MethodsAdults (N = 104, age = 56.6 ± 9.2; 64% female) completed a prospective and retrospective memory questionnaire (PRMQ) and a depression symptom interview at baseline. EM was tracked over 3 months and participants rated adherence using SR. Multiple linear regression evaluated PRMQ as a moderator of the relationship between EM and SR, adjusting for depression and other covariates.ResultsPRMQ was correlated with lower SR (r = ?0.31, p = 0.001), but not with EM. PRMQ moderated the relationship between SR and EM, independent of depression symptoms. At low levels of PRMQ, SR and EM were closely related (β = 0.76, p < 0.001); at high levels of PRMQ the relationship was weaker (β = 0.28, p = 0.02). Participants who under-reported their adherence (SR < EM) had higher PRMQ scores than more concordant reporters (p = 0.016).ConclusionsSR and EM measures were less concordant among adults with T2D who endorsed higher PRMQ scores. Memory complaints may contribute to under-reporting of medication adherence in adults with T2D. 相似文献
2.
3.
4.
5.
6.
7.
8.
9.
《European journal of medical genetics》2021,64(12):104345
BackgroundEpidermolysis bullosa (EB) is a genodermatosis characterized by skin fragility and blisters with variable severity. Patients with Dystrophic EB (DEB) or Junctional EB (JEB) mainly present to clinic due to greater functional impairment. Pathogenic sequence variations in COL7A1 are implicated in DEB.ObjectiveWe have tried to decipher the molecular spectrum and genotype phenotype correlation of 21 Indian patients with EB.MethodsNext generation sequencing (NGS) was performed to determine the pathogenic variants. Sanger sequencing was also done for validation of the variants in eleven individuals.ResultsPathogenic variants were detected in 20 individuals (diagnostic yield of 95%). Majority of them (90%) had sequence variation in COL7A1 while two had pathogenic variants in ITGB4 and KRT14 respectively. Out of the 18 patients confirmed to have DEB, 3 had Dominant DEB (DDEB) whereas 15 patients had Recessive DEB (RDEB). Amongst 23 sequence variations identified, 12 were found to be novel (3 were missense, 5 were premature termination codon variants while 4 were splice-site changes).ConclusionGenotype phenotype correlation was noted with milder manifestations in those with dominant inheritance types. Exact molecular diagnosis can be ascertained by NGS in majority of cases. 相似文献
10.
《The lancet oncology》2022,23(1):125-137