Clinical and experimental observation on treatment of sensorineural deafness with Bushen Conger tablet

Objective: To observe the effect of Bushen Conger (BSCE) tablet, a pure Chinese herbal medicine for reinforcing Kidney, removing blood stasis and opening apertures, in treating sensorineural deafness.Methods: Three hundred and ten patients were treated by BSCE tablet and the effects were observed. At the same time the effects of BSCE tablet on hearing, SOD, LPO, etc. were also assayed in guinea pigs.Results: The clinical total effective rate of BSCE tablet was 71.9%. Animal experiment proved that the drug was effective in preventing and treating toxic deafness induced by aminoglycoside antibiotics.Conclusion: BSCE tablet could cure sensorineural deafness through adjusting the cochlear cyclic neucleotides as well as its SOD level, reducing the LPO level, and raising the thyroid and sexual glandular functions.