全文获取类型
收费全文 | 13319篇 |
免费 | 369篇 |
国内免费 | 50篇 |
专业分类
耳鼻咽喉 | 134篇 |
儿科学 | 1608篇 |
妇产科学 | 503篇 |
基础医学 | 1585篇 |
口腔科学 | 264篇 |
临床医学 | 1236篇 |
内科学 | 1669篇 |
皮肤病学 | 154篇 |
神经病学 | 1518篇 |
特种医学 | 683篇 |
外科学 | 1834篇 |
综合类 | 480篇 |
一般理论 | 2篇 |
预防医学 | 1052篇 |
眼科学 | 262篇 |
药学 | 320篇 |
中国医学 | 21篇 |
肿瘤学 | 413篇 |
出版年
2023年 | 803篇 |
2022年 | 1164篇 |
2021年 | 1128篇 |
2020年 | 1320篇 |
2019年 | 738篇 |
2018年 | 532篇 |
2017年 | 510篇 |
2016年 | 586篇 |
2015年 | 477篇 |
2014年 | 921篇 |
2013年 | 673篇 |
2012年 | 520篇 |
2011年 | 363篇 |
2010年 | 624篇 |
2009年 | 533篇 |
2008年 | 234篇 |
2007年 | 258篇 |
2006年 | 174篇 |
2005年 | 124篇 |
2004年 | 120篇 |
2003年 | 135篇 |
2002年 | 195篇 |
2001年 | 156篇 |
2000年 | 107篇 |
1999年 | 149篇 |
1998年 | 118篇 |
1997年 | 109篇 |
1996年 | 99篇 |
1995年 | 85篇 |
1994年 | 77篇 |
1993年 | 37篇 |
1992年 | 27篇 |
1991年 | 28篇 |
1990年 | 30篇 |
1989年 | 27篇 |
1986年 | 17篇 |
1985年 | 29篇 |
1984年 | 43篇 |
1983年 | 31篇 |
1982年 | 23篇 |
1981年 | 18篇 |
1980年 | 23篇 |
1979年 | 33篇 |
1978年 | 16篇 |
1977年 | 16篇 |
1976年 | 24篇 |
1975年 | 17篇 |
1974年 | 20篇 |
1973年 | 27篇 |
1972年 | 14篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
《Journal of diabetes and its complications》2022,36(8):108260
AimTo verify whether arterial stiffness and endothelial dysfunction influence lower limb muscle strength and gait speed in older adults with type 2 diabetes mellitus (T2DM).MethodsCross-sectional study including seventy-eight older adults with T2DM (aged 67 ± 6 years and 42 % male). Arterial stiffness was assessed using pulse wave velocity (PWV), while endothelial function was measured by flow-mediated dilation (FMD). Lower limb muscle strength and gait speed were assessed using the 30-second chair stand test (30s-CST) and 10-Meter Walk Test, respectively.ResultsBoth PWV (m/s) and FMD (%) were univariately associated with number of repetitions in 30s-CST and gait speed (P < 0.05). After control for age, sex and body mass index, PWV remained associated with repetitions in 30s-CST (95 % CI: ?0.494 to ?0.054; P = 0.015) and gait speed (95 % CI: ?0.039 to ?0.002; P = 0.031). After adjustments for control variables, T2DM duration and glycemic control, FMD was associated with repetitions in 30s-CST (95 % CI: 0.008 to 0.324; P = 0.039) and gait speed (95 % CI: 0.011 to 0.038; P = 0.001).ConclusionIn older adults with T2DM, both arterial stiffness and endothelial dysfunction are associated with decreased leg muscle strength and slower gait speed. 相似文献
4.
5.
《European journal of surgical oncology》2022,48(3):621-631
ObjectivesThe aim of this meta-analysis was to conduct a contemporary systematic review of high quality non-randomised controlled trials to determine the effect of pre-liver transplantation (LT) transarterial chemoembolisation (TACE) on long-term survival and complications of hepatocellular carcinoma (HCC) patients.BackgroundTACE is used as a neoadjuvant therapy to mitigate waitlist drop-out for patients with HCC awaiting LT. Previous studies have conflicting conclusions on the effect of TACE on long-term survival and complications of HCC patients undergoing LT.MethodsCINAHL, Cochrane Controlled Register of Trials, Embase, PubMed, and Web of Science were systematically searched. Baseline characteristics included number of patients outside Milan criteria, tumour diameter, MELD score, and time on the waiting list. Primary outcomes included 3- and 5-year overall and disease-free survival. Secondary outcomes included tumour recurrence, 30-day postoperative mortality, and hepatic artery and biliary complications.ResultsTwenty-one high-quality NRCTs representing 8242 patients were included. Tumour diameter was significantly larger in TACE patients (3.49 cm vs 3.15 cm, P = 0.02) and time on the waiting list was significantly longer in TACE patients (4.87 months vs 3.46 months, P = 0.05), while MELD score was significantly higher in non-TACE patients (10.81 vs 12.35, P = 0.005). All primary and secondary outcomes displayed non-significant differences.ConclusionPatients treated with TACE had similar survival and postoperative outcomes to non-TACE patients, however, they had worse prognostic features compared to non-TACE patients. These findings strongly support the current US and European clinical practice guidelines that neoadjuvant TACE can be used for patients with longer expected waiting list times (specifically >6 months). Randomised controlled trials would be needed to increase the quality of evidence. 相似文献
6.
7.
《Journal of diabetes and its complications》2022,36(9):108265
ObjectiveThere may be gender difference in correlation of diabetes mellitus (DM) and cardiovascular events. We attempt to investigate whether there is gender-heterogeneity in one-year outcomes of atrial fibrillation (AF) patients with DM or not.MethodsPatients who were diagnosed with AF admitted to the emergency departments in the Chinese AF Multicenter Registry study were enrolled. Basic demographics information, initial Blood Pressure and heart rate, medical histories, and treatments of each patient were collected. Follow-up was carried out with a mean duration of one year. The primary endpoint was all-cause mortality and systemic embolism.ResultsA total of 2016 patients were selected from September 2008 and April 2011. All-cause mortality was significantly higher in male AF patients with DM than those without (21.8 % & 13.6 %, P = 0.014). Cox regression analysis showed that there was an interaction between gender and DM for one-year all-cause mortality (P = 0.049). DM was significantly associated with one-year all-cause mortality regardless of univariate analysis (HR = 1.436, 95%CI:1.079–1.911, P = 0.013) or multivariate analysis (HR = 1.418, 95%CI: 1.059–1.899, P = 0.019). For male patients with AF, DM was significantly associated with one-year all-cause mortality (P = 0.048), but not for female patients with AF (P = 0.362).ConclusionDM was independently associated with one-year all-cause mortality in the entire cohort of AF patients. This association was found mainly in male patients with AF, but not in female patients. DM management programs may need to reflect gender difference. 相似文献
8.
9.
10.