Event-triggered synchronization strategy for complex dynamical networks with the Markovian switching topologies

This paper concerns the synchronization problem of complex networks with the random switching topologies. By modeling the switching of network topologies as a Markov process, a novel event-triggered synchronization strategy is proposed. Unlike the existing strategies, the event detection of this strategy only works at the network topology switching time instant, which can significantly decrease the communication frequency between nodes and save the network resources. Under this strategy, the synchronization problem of complex network is equivalently converted to the stability of a class of Markovian jump systems with a time-varying delay. By using the Lyapunov–Krasovskii functional method and the weak infinitesimal operation, a sufficient condition for the mean square synchronization of the complex networks subject to Markovian switching topologies is established. Finally, a numerical simulation example is provided to demonstrate the theoretical results.     

普通内科下呼吸道感染病原菌分布与耐药性分析

目的:探讨我院普通内科下呼吸道感染患者痰培养阳性标本的病原菌种类和耐药性情况,以规范使用抗生素。方法:回顾分析2009年10月~2010年4月49例患者的痰培养阳性标本病原菌种类和药敏试验结果。结果:检出致病细菌65株(包括G-杆菌47株、G+球菌18株)、真菌19株;多重耐药菌株十分普遍。结论:为避免盲目使用抗生素,及时、规范进行病原菌的采集和培养十分必要。     

新型送药车的研制与临床应用

随着护理模式的转变，陪住率的控制与“以病人为中心”的宗旨之间的矛盾日益突出。为了解决这一矛盾，我院采取了一系列措施，如后勤、检验、医技等科室时刻为临床服务，如成立药品配送中心，明显减少了护理人员及病人家属的负担。但在运行过程中，应用传统地送药车虽能基本满足病房使用要求，由于存在储物空间少，结构简单，且所送药品数量大、品种多，不易分类放置且易破损，新型送药车的应用能把药品按剂型、     

不同清洗方法对腹腔镜手术器械灭菌效果的影响

目的探讨不同清洗方法对腹腔镜手术器械清洗和灭菌效果的影响。方法选择2010年5月-2012年2月使用后的腹腔镜手术器械2 499件,将其随机分为A组833件、B组833件、C组833件,分别采用单纯手工清洗方法、手工加酶清洗方法、加酶超声清洗方法,清洗效果监测采用目测检查,3组器械均采用高压蒸汽灭菌器灭菌,灭菌后采用营养琼脂培养法对腹腔镜手术器械进行细菌学检测,数据采用SPSS13.0软件进行统计分析。结果清洗效果合格率A、B、C 3组分别为93.9%、97.4%、100.0%,C组清洗合格率明显优于B组和A组,差异有统计学意义(P<0.05);器械灭菌后A、B、C 3组细菌学检测合格率依次为95.7%、97.2%、100.0%,C组细菌学检测合格率明显优于B组和A组,差异有统计学意义(P<0.05)。结论超声联合多酶清洗显著提高器械的清洗质量,可作为一种有效、安全、简便的清洗方法在临床中广泛应用。     

Changes in lung cancer incidence by sex and smoking status in China: a multicentre observational study

Background

Lung cancer is traditionally more prevalent in elderly people, men, and smokers, and is usually diagnosed at an advanced stage. However, as low-dose CT (LDCT) lung cancer screening is increasingly popular in some regions of China, and since it might lead to the detection of more small-sized lung cancers, we hypothesised the spectrum of lung cancer might change.

急性脑梗死患者血清C反应蛋白与C_3水平变化及意义

目的进一步探讨急性脑梗死(ACI)发生、发展机制。方法选择ACI患者118例(ACI组)和健康体检者56例(对照组),应用免疫比浊法测定血清C反应蛋白(CRP)和C3水平。结果ACI组血清CRP和C3水平明显高于对照组,且随病情进展及梗死面积增大而升高;随血清CRP和C3水平升高,进展型ACI发病率升高。结论血清CRP和C3水平升高在ACI发病及进展中发挥重要作用,可作为预测ACI严重程度及进展的相关性生化指标。     

A new approach for transseptal catheterization in patients undergoing percutaneous balloon mitral valvuloplasty

AIMS: To evaluate the safety and efficacy of a new approach for transseptal catheterization in patients undergoing percutaneous balloon mitral valvuloplasty (PBMV). METHODS: One hundred and two patients with rheumatic mitral stenosis were randomized into two groups. In the study group (RA approach), an imaginary horizontal line was drawn from the top end of the tricuspid valve under anteroposterior fluoroscopic view. The intersection of the horizontal line and the right edge of the corresponding thoracic vertebra was defined as the upper border of the Fossa ovalis. The atrial septum was punctured from a point 0.5 cm below the upper border of the Fossa ovalis. In the control group (LA approach), an imaginary horizontal line was drawn between the upper and middle third of the left atrium, and the intersection of this horizontal line and the right edge of the corresponding thoracic vertebra was used as an atrial septum puncture point. RESULTS: Atrial septum puncture succeeded in all patients in the study group and in 72.6% of the patients in the control group (p < 0.01). The average fluoroscopy times for transseptal catheterization in the study and the control groups were 2.0 +/- 0.5 and 3.0 +/- 1.0 min, respectively (p < 0.01). Transseptal catheterization was subsequently achieved using the RA approach in the 14 patients from the control group in whom the LA approach failed. CONCLUSIONS: The RA approach is a safe and effective means for transseptal catheterization in patients undergoing PBMV.     

彩色多普勒超声引导下经皮门静脉穿刺留置导管的临床应用

目的探讨彩色多昔勒超声引导下经皮经肝穿刺门静脉留置导管的临床应用价值。方法100例肝细胞癌或转移癌患者，在彩色多普勒超声引导下经皮经肝穿刺门静脉置人中心静脉导管，观察穿刺及置管成功率、导管留置天数、并发症发生率和治疗效果。结果在100例患者中，穿刺一次成功率和置管一次成功率为98．0％；早期导管留置天数为7-14d，平均9．2±2．7d，改进后为23-60d，平均44．7±13．5d；无严重并发症发生。经门静脉注药治疗原发性肝癌和转移性肝癌的疗效优于外周静脉给药。讨论该方法可重复门静脉给药，能增加局部药物浓度，提高药物治疗的效果．并且安全、可靠，无严重并发症。     

bcl-xl基因蛋白在非小细胞肺癌中的表达及意义

目的探讨非小细胞肺癌（non-small cell lung cancer,NSCLC）中bcl-xl基因蛋白的表达及意义。方法应用组织芯片技术制成32例NSCLC组织芯片,采用免疫组织化学技术检测30例正常肺组织,32例NSCLC癌组织中bcl-xl基因蛋白的表达。结果bcl-xl在NSCLC组织中表达阳性率为81.3%,显著高于正常肺组织（6.7%,P〈0.05）。bcl-xl蛋白表达与细胞分化程度有密切关系（χ^2=3.87,P〈0.05）,与肿瘤TNM分期、淋巴结转移、肿瘤组织学类型、年龄、性别无明显关系（P〉0.05）。结论bcl-xl基因蛋白表达增强可能与NSCLC发生及早期发展有关。