脑血管狭窄患者介入治疗后并发症原因分析及护理

目的探究脑血管狭窄患者介入治疗后并发症原因分析及护理。方法将我院2011年1月~2012年4月收治的43例脑血管狭窄病患作为研究对象,对他们采用介入治疗(支架植入术)之后,有11例发生了并发症,类型为颈动脉窦反应(3)、穿刺部位出血(2)、脑过度灌注综合征(3)、脑血管痉挛(3)。针对这11例并发症病患发病原因进行分析,并采取对症措施加以护理,并对疗效进行观察总结。结果 11例并发症病患经过了对症护理之后,恢复状况良好,并未出现其它并发症。结论针对脑血管狭窄病患介入治疗后出现了并发症,我们应及时对并发症原因进行分析,在掌握并发症因的前提下采取对症的护理,方能有效避免其它并发症的发生,提高病患的恢复效果。     

预见性护理在糖尿病性白内障患者围术期护理中的应用

目的探究预见性护理在糖尿病性白内障患者围术期护理中的应用效果。方法从2018年5~11月聊城市第三人民医院收治的糖尿病性白内障手术患者中选出92例,随机分成两组,对照组采取常规护理,观察组采取“常规护理+预见性护理”,各46例。比较两组患者的并发症发生率、生活质量。结果观察组患者的并发症发生率显著低于对照组,生活质量评分显著高于对照组,差异均有统计学意义(均P<0.05)。结论预见性护理可显著降低糖尿病性白内障患者并发症发生率,提高患者生活质量。     

CXCR5+ CD8+ T cells could induce the death of tumor cells in HBV-related hepatocellular carcinoma

The follicular CXCR5⁺ CD8⁺ T cells have recently emerged as a critical cell type in mediating peripheral tolerance as well as antiviral immune responses during chronic infections. In this study, we investigated the function of CXCR5⁺ CD8⁺ T cells in HBV-related hepatocellular carcinoma patients. Compared to CXCR5⁻ CD8⁺ T cells, CXCR5⁺ CD8⁺ T cells presented elevated PD-1 expression but reduced Tim-3 and CTLA-4 expression. Upon anti-CD3/CD28 stimulation, CXCR5⁺ CD8⁺ T cells demonstrated higher proliferation potency than CXCR5⁻ CD8⁺ T cells, especially after PD-1 blockade. CXCR5⁺ CD8⁺ T cells also demonstrated significantly higher granzyme B synthesis and release, as well as higher level of degranulation. Tumor cells were more readily eliminated by CXCR5⁺ CD8⁺ T cells than by CXCR5⁻ CD8⁺ T cells. Interestingly, we found that B cells were more resistant to CXCR5⁺ CD8⁺ T cell-mediated killing than tumor cells, possibly through IL-10-mediated protection. In addition, the CXCR5⁺ CD8⁺ T cell-mediated cytotoxic effects on tumor cells could be significantly enhanced by PD-L1 blockade. Together, we presented that in patients with in HBV-related hepatocellular carcinoma, CXCR5⁺ CD8⁺ T cells could mediate tumor cell death more potently than the CXCR5⁻ CD8⁺ T cells in vitro while the autologous B cells were protected.     

浅谈医院行政管理人员绩效考核

行政管理人员绩效考核是医院人力资源管理的重要内容,也是医院建立现代管理制度的客观要求,在规范医院内部运行机制、创新医院用人制度、提高人力资源管理水平方面发挥着不容忽视的作用。该文从分析医院行政管理人员绩效考核存在的问题入手,提出完善绩效考核的对策建议,期望对提升行政管理人员工作效率,助力医院稳定持续发展有所帮助。     

The mediating role of emotional intelligence between negative life events and psychological distress among nursing students: A cross-sectional study

BackgroundPrevious studies have highlighted that negative life events and emotional intelligence are significant predictors of mental health. However, whether emotional intelligence mediates the relationship between negative life events and psychological distress among nursing students have not been given adequate attention.ObjectivesTo explore the relationship among negative life events, emotional intelligence and psychological distress and to examine the mediating role of emotional intelligence in psychological distress among Chinese nursing students.DesignA cross-sectional survey using convenience sampling.Settings and ParticipantsA total of 467 nursing students who were enrolled in a university in mainland of China.MethodsA structured questionnaire was administered from September–November in 2013 to participants who consented to participate in the study. Independent variables were personal variables, emotional intelligence and negative life events. Outcome variable was psychological health. The means and standard deviations were computed. Student's t-test and one-way analysis of variance (ANOVA) were performed, to test the differences among the demographic characteristics on the psychological distress scores. Pearson correlation analyses and hierarchical regression analyses were performed.ResultsNegative life events were positively associated with psychological distress. Emotional intelligence was negatively associated with psychological distress and negative life events. Emotional intelligence mediated the relationship between negative life events and psychological distress.ConclusionsThe findings support the theory of Salovey and his colleagues, and provide evidence for emotional intelligence as a factor that buffers effects of negative life events on psychological distress.