Traumatic anterior hip dislocation in a 12-year-old child

Hip dislocation in children can occur congenitally in isolation or in conjunction with other congenital abnormalities.Traumatic hip dislocations in children are relatively uncommon and anterior disloca...     

Outcome of rail fixator system in reconstructing bone gap

Background:

Bone loss following open fracture or infected gap nonunion is a difficult situation to manage. There are many modes of treatment such as bone grafting, vascularized bone grafting and bone transport by illizarov and monolateral fixator. We evaluated the outcome of rail fixator treatment in reconstructing bone and limb function. We felt that due to problems such as heavy apparatus, persistent pain, deformity of joints and discomfort caused by an Ilizarov ring fixator, rail fixator is a good alternative to treat bone gaps.

Materials and Methods:

20 patients (17 males and 3 females with mean age 30.5 years) who suffered bone loss due to open fracture and chronic osteomyelitis leading to infected gap nonunion. Ten patients suffered an open fracture (Gustilo type II and type III) and 10 patients suffered bone gap following excision of necrotic bone after infected nonunion. There were 19 cases of tibia and one case of humerus. All patients were treated with debridement and stabilization of fracture with a rail fixator. Further treatment involved reconstructing bone defect by corticotomy at an appropriate level and distraction by rail fixator.

Result:

We achieved union in all cases. The average bone gap reconstructed was 7.72 cm (range 3.5-15.5 cm) in 9 months (range 6-14 months). Normal range of motion in nearby joint was achieved in 80% cases. We had excellent to good limb function in 85% of cases as per the association for the study and application of the method of ilizarov scoring system[ASAMI] score.

Conclusion:

All patients well tolerated rail fixator with good functional results and gap reconstruction. Easy application of rail fixator and comfortable distraction procedure suggest rail fixator a good alternative for gap reconstruction of limbs.     

Burden of noncommunicable diseases and implementation challenges of National NCD Programmes in India

BackgroundOut of the total deaths globally, noncommunicable diseases (NCDs) account for 72% of the deaths. In India, as per the global burden of disease 2016 estimates, NCDs contributed to 62% of the deaths and 55% of the disability-adjusted life years, thereby posing a huge burden. Before 2010, there was no integrated programme, which addresses these NCDs, but there were many programmes parallelly running and catering to different aspects of these NCDs. Now almost 13 programmes are directly or indirectly contributing to the NCD prevention and control with many implementation challenges.MethodsA review on the status of NCD burden estimates globally and nationally was undertaken. The National NCD Programme and other strategies associated with addressing the NCDs were searched using the search engines PubMed and Google Scholar along with the websites of national ministries, government portals and meeting proceedings.ResultsHealth is a state subject, with National Health Mission (NRHM/NUHM) as a flagship programme of Ministry of Health and Family Welfare. There are 13 programmes contributing to NCD prevention and control directly or indirectly and the major one is the National Programme for prevention and control of cancer, diabetes, cardiovascular diseases and stroke (NPCDCS). The other initiatives taken for NCD prevention and control include the National Action Plan to achieve NCD targets by 2025 and development of Multisectoral Action Plan (2017–2022). The infrastructure for NPCDCS includes 524 district NCD cells, 565 district NCD clinics, 167 district cardiac care units, 164 district day care centres and 2759 Community Health Centre NCD clinics. The key challenges are with trained human resources for the screening of the NCDs, low budget allocation and utilisation, lack of access to diagnostics and regular supply of essential medicines. There is also poor focus on health promotion, multisectoral participation, surveillance, monitoring and evaluation of the programme at different levels of health care delivery.ConclusionThe government has taken different initiatives for the prevention and control but effective implementation is the major challenge in India. A health system strengthening with focus on health promotion in different settings, robust surveillance and access to individual clinical services is required. Collaborations with ministries, multisectoral approach, strengthening of referral system along with involvement/training of grassroot level workers who efficiently implement are needed. Bolstering of screening, diagnostic and treatment service will be fruitful.     

A Comparative Study of Bone Marrow Squash and Wedge Aspiration Smears

Bone marrow examination entails study of aspirate smears, touch imprints and trephine biopsy. Bone marrow aspirate smears can be prepared by the squash (crush) or wedge method. Both techniques have their own advantages and disadvantages. There is paucity of studies that have compared these smear types. This study was conducted over a period of one year. Two hundred and five bone marrow aspirates were included. Both squash and wedge smears were made. Blinded slide review was done. Bone marrow cellularity, megakaryocyte number, myeloid to erythroid (M:E) ratio, morphology and final diagnosis on each smear type was compared. Chi square test, t-test and Kappa were applied to study the agreement between the wedge and squash smears. Among the 205 patients studied, squash smears showed significant over estimation of cellularity and megakaryocyte number (p < 0.05). There was no significant difference (p > 0.05) in the M:E ratio and morphological scores. Most patients (188/205 [91.7%]) showed complete diagnostic concordance while 17 (8.3%) patients had discrepancy in diagnosis between the squash and wedge smears. In 8 (3.9%) of these, major discrepancies were seen while 9 (4.4%) patients had minor discrepancies. Bone marrow cellularity and megakaryocyte numbers were underestimated in wedge smears with no differences in M:E ratio or morphology. Acceptable agreement for diagnosis was seen for patients with most disorders. Major diagnostic discrepancies were seen in patients with lesions known to have focal distribution—lymphoma, myeloma and tuberculosis (granulomas). Both squash and wedge smears should be studied for bone marrow examination.     

Correlation between diastolic impairment and lipid metabolism in mild-to-moderate hypertensive postmenopausal women

BackgroundMany cardiovascular risk factors are found in hypertensive patients. The aim of this study was to evaluate the correlation between cardiac abnormalities (ie, diastolic and left ventricular hypertrophy) with other cardiovascular risk factors in postmenopausal women with hypertension.MethodsA total of 200 consecutive postmenopausal women (mean age 47.5 ± 4 years) with mild-to-moderate hypertension that had never been treated were studied. Mean systolic pressure was 163 ± 15 mm Hg and mean diastolic pressure 97 ± 75 mm Hg. All subjects underwent M-mode two-dimensional echocardiography and cardiac Doppler. The following measurements were made: peak velocity of early left ventricular filling (E); peak velocity of late ventricular filling (A), and the ratio between early and late flow velocity peaks (E/A). The E/A ratio was then normalized for heart rate (E/Ac). Left ventricular mass index normalized for body surface was also measured. In each patient, total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), and plasma triglycerides were measured. We evaluated the correlation of E/Ac and left ventricular mass index (LVMI) with the following variables: total cholesterol, HDL, LDL, triglyceridemia, smoking status, systolic and diastolic blood pressure, and body mass index.ResultsA significant negative correlation with total cholesterol (r = −0.15, P < .05) and LDL (r = −0.20; P = .005), as well as a significant positive correlation with HDL (r = 0.20, P < .01) were found. No other variable was significantly correlated with E/A. There was no correlation between LVMI and any variable analyzed.ConclusionIn postmenopausal women with mild-to- moderate hypertension, high total cholesterol levels and low HDL levels are associated with impaired diastolic function.