首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   9639篇
  免费   227篇
  国内免费   27篇
耳鼻咽喉   15篇
儿科学   153篇
妇产科学   221篇
基础医学   918篇
口腔科学   133篇
临床医学   1064篇
内科学   2104篇
皮肤病学   105篇
神经病学   503篇
特种医学   456篇
外科学   607篇
综合类   40篇
预防医学   2294篇
眼科学   70篇
药学   574篇
中国医学   20篇
肿瘤学   616篇
  2024年   13篇
  2023年   746篇
  2022年   917篇
  2021年   859篇
  2020年   1144篇
  2019年   621篇
  2018年   424篇
  2017年   562篇
  2016年   524篇
  2015年   474篇
  2014年   721篇
  2013年   498篇
  2012年   253篇
  2011年   125篇
  2010年   371篇
  2009年   363篇
  2008年   112篇
  2007年   151篇
  2006年   103篇
  2005年   56篇
  2004年   46篇
  2003年   51篇
  2002年   71篇
  2001年   76篇
  2000年   44篇
  1999年   57篇
  1998年   79篇
  1997年   58篇
  1996年   65篇
  1995年   56篇
  1994年   29篇
  1993年   25篇
  1992年   13篇
  1991年   16篇
  1990年   13篇
  1989年   13篇
  1988年   25篇
  1987年   22篇
  1986年   30篇
  1985年   7篇
  1984年   15篇
  1983年   8篇
  1982年   9篇
  1981年   7篇
  1980年   8篇
  1979年   4篇
  1978年   2篇
  1977年   4篇
  1976年   3篇
排序方式: 共有9893条查询结果,搜索用时 12 毫秒
1.
2.
IntroductionTreatment satisfaction of men receiving phosphodiesterase 5 inhibitors (PDE5) for erectile dysfunction (ED) and their partners is essential to successful long‐term therapy.AimThis study aims to assess treatment satisfaction, in men with a partial response to on‐demand (PRN) PDE5 and their female partners, following tadalafil 5 mg once daily or placebo.MethodsThe study was randomized, double‐blind, parallel, and placebo‐controlled in men primarily with mild to moderate ED. Treatment satisfaction was assessed following a 4‐week maximum dose PRN lead‐in, 4‐week nondrug washout, and treatment through 12 weeks. Men were ≥18 years old with ED for ≥3 months and International Index of Erectile Function Erectile Function score of ≥17 and <26 at screening and <26 following PRN lead‐in.Main Outcome MeasuresTreatment satisfaction was assessed using the Treatment Satisfaction Scale (TSS) for patients and partners. TSS domain scores range from 0 to 100, with higher values indicating greater satisfaction. Statistical comparisons were made using analysis of covariance.ResultsTreatment satisfaction was significantly greater with tadalafil once daily vs. placebo across all TSS domains for both patients and their partners (all P < 0.001). For patients, mean scores for the TSS domains Confidence to Complete Sexual Activity and Satisfaction with Orgasm ranged from 53.7 to 57.8 after the PRN lead‐in and 26.7 to 31.9 following the nondrug washout. Following randomized treatment, scores for tadalafil and placebo were 55.4 and 32.6, respectively, for Confidence to Complete Sexual Activity and 57.5 and 37.9, respectively, for Satisfaction with Orgasm. Results were comparable for other TSS domains and between men and their partners.ConclusionsTreatment satisfaction was comparable for tadalafil 5 mg once daily and PRN PDE5 for both patients and female partners, suggesting that tadalafil once daily is a viable therapy option for men with ED who had a partial response to PRN PDE5 therapy. Burns PR, Rosen RC, Dunn M, Baygani SK, and Perelman MA. Treatment satisfaction of men and partners following switch from on‐demand phosphodiesterase type 5 inhibitor therapy to tadalafil 5 mg once daily. J Sex Med 2015;12:720–727.  相似文献   
3.
Alveolar soft part sarcoma is a rare malignancy mainly localized in the deep soft tissue of the extremities. This is the first report of an alveolar soft part sarcoma originating from the sphincter ani externus. A 27-year-old pregnant woman presented with a tumour located in the right ischiorectal fossa which had rapidly enlarged during pregnancy 6 years after first detection. Admitted to our hospital, she presented with a continuous strong vaginal bleeding, multiple pulmonal metastases and an inoperable local tumour mass. Palliative chemotherapy was unsuccessful, control of local bleeding was only possible with multiple embolisations. The patient died 43 months after initial diagnosis. Our intention is to point out the remarkable origin, a rapid tumour growth during pregnancy, and the possibility of controlling massive tumour bleeding by embolisation.  相似文献   
4.
5.
《IBS, Immuno》2005,20(6):360-371
Influence of maternal smoking on newborn's behaviour: determination urinary nicotine metabolites levels in mothers and infants.Objective. – Effects of smoking during pregnancy on newborn's behaviour at 2 or 3 days. Intoxication? Withdrawal?Population and method. – Urinary cotinine levels were measured using DPC® technique in 142 mothers during labour and in their 138 normal, full-term newborns kept with their mothers at about 3 days. Infants' Finnegan scores were estimated, Lamour/Barraco tests, too.Results. – There are significant correlations: maternal cotinine (ng/mg) = 382,67 + 264,79 cigarettes/day, R = 0,70, P < 0,001; newborn cotinine (ng/mg) = 74,28 + 68,49 cigarettes/day, R = 0,69, P < 0,001; newborn cotinine (ng/mg) = 57,59 + 0,18 maternal cotinine (ng/mg), R = 0,73, P < 0,001. Newborns' cotinine concentrations (47% corresponds with smokers' levels) are with breast-milk 4,94 times lower than that of their mothers vs 3,65 with artificial milk. Incidence of colic increases (P = 0,008) and the neurologic scores average decreases (P = 0,059).Conclusions. – Newborns' high cotinine levels, digestive and neurologic symptoms modification suggest tobacco intoxication. Therefore withdrawal would appear later. Breast-milk seems to accelerate cotinine elimination.  相似文献   
6.
7.
8.
9.
Epidural blockade in children has become more popular for postoperative analgesia in recent years owing to increased experience, greater confidence and the development of appropriate equipment. In the UK, approximately 2000 lumbar epidural and continuous caudal blocks are performed each year. Spinal anaesthesia remains popular for babies at risk of postoperative apnoea, but is being superseded by light general anaesthesia with desflurane or sevoflurane combined with caudal blockade. Contraindications to neuraxial blockade include patient or parental refusal, coagulation abnormalities, septicaemia, raised intracranial pressure, meningitis, infection at the entry site, allergy to local anaesthetics, myelomeningocele (spina bifida) and abnormal sacral anatomy for a caudal epidural.  相似文献   
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号