全文获取类型
收费全文 | 7965篇 |
免费 | 235篇 |
国内免费 | 19篇 |
专业分类
耳鼻咽喉 | 34篇 |
儿科学 | 275篇 |
妇产科学 | 64篇 |
基础医学 | 395篇 |
口腔科学 | 55篇 |
临床医学 | 2935篇 |
内科学 | 1436篇 |
皮肤病学 | 17篇 |
神经病学 | 316篇 |
特种医学 | 150篇 |
外科学 | 1857篇 |
综合类 | 113篇 |
预防医学 | 261篇 |
眼科学 | 11篇 |
药学 | 218篇 |
中国医学 | 8篇 |
肿瘤学 | 74篇 |
出版年
2024年 | 10篇 |
2023年 | 511篇 |
2022年 | 690篇 |
2021年 | 923篇 |
2020年 | 849篇 |
2019年 | 438篇 |
2018年 | 355篇 |
2017年 | 341篇 |
2016年 | 430篇 |
2015年 | 325篇 |
2014年 | 501篇 |
2013年 | 375篇 |
2012年 | 292篇 |
2011年 | 188篇 |
2010年 | 317篇 |
2009年 | 258篇 |
2008年 | 132篇 |
2007年 | 167篇 |
2006年 | 173篇 |
2005年 | 96篇 |
2004年 | 73篇 |
2003年 | 63篇 |
2002年 | 87篇 |
2001年 | 62篇 |
2000年 | 68篇 |
1999年 | 85篇 |
1998年 | 62篇 |
1997年 | 41篇 |
1996年 | 53篇 |
1995年 | 47篇 |
1994年 | 28篇 |
1993年 | 18篇 |
1992年 | 23篇 |
1991年 | 21篇 |
1990年 | 15篇 |
1989年 | 23篇 |
1988年 | 18篇 |
1987年 | 14篇 |
1986年 | 9篇 |
1985年 | 11篇 |
1984年 | 7篇 |
1983年 | 5篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 4篇 |
1976年 | 3篇 |
排序方式: 共有8219条查询结果,搜索用时 15 毫秒
1.
Yosuke Homma Takashi Shiga Hiraku Funakoshi Dai Miyazaki Atsushi Sakurai Yoshio Tahara Ken Nagao Naohiro Yonemoto Arino Yaguchi Naoto Morimura 《The American journal of emergency medicine》2019,37(2):241-248
Objective
This study assessed the association between the timing of first epinephrine administration (EA) and the neurological outcomes following out-of-hospital cardiac arrests (OHCAs) with both initial shockable and non-shockable rhythms.Methods
This was a post-hoc analysis of a multicenter prospective cohort study (SOS-KANTO 2012), which registered OHCA patients in the Kanto region of Japan from January 2012 to March 2013. We included consecutive adult OHCA patients who received epinephrine. The primary result included 1-month favorable neurological outcomes defined as cerebral performance category (CPC) 1 or 2. Secondary results included 1-month survival and return of spontaneous circulation (ROSC) after arrival at the hospital. Multivariable logistic regression analysis determined the association between delay per minute of the time from call to first EA in both pre- or in-hospital settings and outcomes.Results
Of the 16,452 patients, 9344 were eligible for our analyses. In univariable analysis, the delay in EA was associated with decreased favorable neurological outcomes only when the initial rhythm was a non-shockable rhythm. In multivariable analyses, delay in EA was associated with decreased ROSC (adjusted odds ratio [OR] for one minute delay, 0.97; 95% confidence interval [CI], 0.96–0.98) and 1-month survival (adjusted OR, 0.95; 95% CI, 0.92–0.97) when the initial rhythm was a non-shockable rhythm, whereas during a shockable rhythm, delay in EA was not associated with decreased ROSC and 1-month survival.Conclusions
While assessing the effectiveness of epinephrine for OHCA, we should consider the time-limited effects of epinephrine. Additionally, consideration of early EA based on the pathophysiology is needed. 相似文献2.
3.
4.
5.
6.
7.
8.
9.
BACKGROUND/PURPOSE: Abdominal nontuberculous mycobacterial infection is a rare condition. Continuous ambulatory peritoneal dialysis (CAPD)-associated peritonitis is the most common manifestation of infection due to nontuberculous mycobacteria (NTM). There are limited data on the clinical manifestations of nontuberculous mycobacterial infection. This study investigated the diagnostic features, clinical presentation, mycobacteriology, treatment and outcome of all abdominal NTM infections treated over a 7-year period at a major teaching hospital in Taiwan. METHODS: The medical records of all patients with a diagnosis of abdominal NTM infection from January 1997 through to December 2003 were retrospectively reviewed. RESULTS: All 11 patients with abdominal NTM infections identified during the 7-year period were included. Among these patients, six were male and five were female, with a mean age of 64.5 years. The disease manifested as peritonitis (9 patients, 82%), splenic abscess (1, 9%), or perirenal abscess (1, 9%). Most patients (73%) had underlying malignancy, most often hepatoma (45%). Immunocompromised status (liver cirrhosis, malignancy, acquired immunodeficiency syndrome) was noted in 10 patients (91%). None of our patients who developed NTM peritonitis had received CAPD. The peritoneal fluid appearance varied considerably, with no particular predominance of clear, turbid, bloody, or chylous findings. Rapidly growing mycobacteria were the major etiology (46%) of abdominal NTM infection, and Mycobacterium abscessus played a major role (27%). Overall, eight patients died, and only one patient survived longer than 1 year. Seven patients (64%) died before diagnosis. CONCLUSION: Abdominal NTM infection is frequently overlooked because of its rarity and nonspecific symptoms, with consequent delays in diagnosis and treatment. In immunocompromised patients with ascites from any cause (liver cirrhosis, malignant ascites, etc.), NTM peritonitis should be considered early in the differential diagnosis of symptoms including fever, abdominal pain and weight loss. The poor prognosis of abdominal NTM infection appears to be related to the severity of underlying conditions, most often malignancy. 相似文献
10.