腰椎间盘突出症治疗方法与肌电图变化的相关性研究

腰椎间盘突出症(lumbar disc herniation，LDH)是导致腰腿痛的主要病因，本研究对具有典型临床症状、相应体征及MR或CT等影像学资料确诊的LDH，采用规范化非手术治疗，经规范化保守治疗无效者选用手术治疗，治疗前后均行肌电图(elec-tromyograptly，EMG)检查，旨在探讨肌电图变化与治     

双眼外直肌后徙矫正大角度外斜视

本文报告２０例大角度（≥６０△）外斜视，施行双眼外直肌同时等量后徙（多数患者采用超常量后徙）及非注视眼内直肌切除术。一次手术正位率９０％。外转有轻度不足现象，但不影响其外观及向前方注视。避免了双眼分次手术，维持了双眼对称性运动。     

Immunogenicity of four Haemophilus influenzae type b conjugate vaccines in 17- to 19-month-old children

OBJECTIVE: To compare the immunogenicity of four Haemophilus influenzae type b (Hib) conjugate vaccines in different populations of 17- to 19-month-old children in the United States. DESIGN: Four immunogenicity trials with sera were assayed in one laboratory. Trials 1 and 2 each compared one vaccine in two regions, and trials 3 and 4 were randomized comparisons of multiple vaccines within a region. SUBJECTS: A convenience sample of 313 healthy children recruited from pediatric practices in Minneapolis, Minn., Dallas and Houston, Tex., and Sellersville, Pa. MEASUREMENTS AND RESULTS: Children with prevaccination antibody greater than 0.15 microgram/ml showed higher antibody responses to vaccination than children with less than or equal to 0.15 microgram/ml (p less than 0.001). Among the former, there were no significant differences in antibody response to vaccination with the different conjugates within any of the trials. Among children with less than or equal to 0.15 microgram/ml of antibody before vaccination, there were no significant differences in the geometric mean antibody responses of children in trial 1 vaccinated with polyribosylribitol phosphate-diphtheria toxoid (PRP-D) in Dallas or in Minneapolis, or of children in trial 3 in Dallas randomly assigned to receive Hib oligosaccharide-CRM197 (HbOC) or PRP-D. In contrast, in trial 2, children given PRP-tetanus toxoid (PRP-T) in Pennsylvania had a significantly higher geometric mean antibody response than children given PRP-T in Houston (13.5 vs 3.0 micrograms/ml; p = 0.005). In trial 4 in Minneapolis, the geometric mean antibody response was highest in children randomly assigned to receive PRP-outer membrane protein (OMP) (9.3 micrograms/ml), followed by PRP-D (5.0 micrograms/ml) and HbOC (2.3 micrograms/ml) (PRP-OMP vs HbOC; p = 0.005). In all four trials, IgG1 responses predominated compared with IgG2 responses. CONCLUSIONS: All four conjugate vaccines are immunogenic in children 17 to 19 months of age. However, the magnitude of the anticapsular antibody response varied by vaccine type, the level of antibody in prevaccination sera, and geographic location.     

口溃液治疗复发性口腔溃疡208例疗效观察

口溃液主要成分为三氯化铁。本品经对２０８例复发性口腔溃疡患者的临床疗效观察，总有效率为９７．１％，并具有显效迅速，作用持久、涂抹方便等优点。     

攀枝花市公共场所基本卫生状况分析

本文攀枝花市公共场所环境卫生质量进行了调查和分析。结果表明：空气中细菌总数超标８２．７％，气湿超标７１％，风速超标５４．３％，噪声超标４５．６％，ＣＯ２超标１３．６％，ＣＯ超标９％。为改善公共场所卫生质量提出了建议。     

舒芬太尼复合罗哌卡因用于腹部手术后硬膜外自控镇痛

目的:研究舒芬太尼复合罗哌卡因用于腹部手术后硬膜外自控镇痛(patient-controlled analgesia,PCA)的效果和不良反应。方法:选择全身麻醉耐受能力(ASA)Ⅰ~Ⅱ级择期行腹部手术的88例,随机分为舒芬太尼组和芬太尼组。两组术后分别复合0.2%罗哌卡因行硬膜外PCA,观察并记录两组术后16、32小时的静息、咳嗽、活动时的视觉模拟评分(VAS),实际镇痛时间以及术后恶心、呕吐、尿潴留、呼吸抑制、皮肤瘙痒等不良反应。结果:舒芬太尼组术后16、32小时的静息、咳嗽、活动时的VAS评分与芬太尼组比较,差异具有显著统计学意义(P<0.05);在术后镇痛不良反应中,芬太尼组呼吸抑制发生率为17.8%,舒芬太尼组发生率为0,两组比较,差异具有显著统计学意义(P<0.05)。实际镇痛时间:舒芬太尼组为(46.51±1.32)小时,芬太尼组为(36.24±2.28)小时,两组比较,差异具有非常显著统计学意义(P<0.01)。结论:舒芬太尼复合罗哌卡因用于腹部术后硬膜外PCA较芬太尼复合罗哌卡因镇痛效果好,不良反应小,安全性高。     

胫腓骨下段开放性粉碎骨折的治疗(附20例临床报告)

目的探讨胫腓骨下段开放性粉碎骨折的综合治疗。方法20例胫腓骨下段开放性粉碎骨折采用半环槽式外固定器固定、皮瓣转移、腓骨内移、骨折端加压并同期行上干骺端骨延长等综合治疗方法。结果伤口均一期愈合，所有皮瓣均成活，骨折临床愈合平均时间19周，7例因严重骨缺损经骨折端加压并同期行上干骺端骨延长后肢体均恢复正常长度。无1例针眼感染和血管、神经损伤。临床优良率为90％(18／20)。结论a)半环槽外固定器能克服胫腓骨下段开放性粉碎骨折的治疗困难，具有立体均衡固定。刚性可调，避免肢体受压。便于再次创面处理以及同期行骨折端加压和肢体延长等优点。b)半环槽式外固定器结合皮瓣转移、腓骨内移以及骨折端加压并同期行上干骺端骨延长等综合治疗方法是胫腓骨下段开放性粉碎骨折可选择的较好治疗措施之一。     

硝基化合物还原、氢化的研究 Ⅳ.用Fe~(3+)催化转移氢化3,3′-二硝基-4,4′-二氨基二苯醚

以Fe~(3+)代替Pd-C和Raney Ni为催化剂、水合肼为供氢体、3,3′-二硝基-4,4′-二氨基二苯醚为受氢体、甲醇为溶剂,进行催化转移氢化反应,产物3,3′,4,4′-四氨基二苯醚(TADPO)质量好,得率可达80%。此外,还对反应温度、时间、以及水合肼、催化剂、溶剂用量,水合肼浓度、催化剂重复使用等影响因素进行了研究,获得了较佳工艺条件。本法制得的TADPO与均苯四甲酸二酐缩聚可制得性能良好的聚眯唑吡咙。     

长沙地区孕妇CMV感染状况及其临床追踪观察

研究了７７例长沙地区孕、产妇的宫颈排毒（ＣＭＶ）情况及母、婴的免疫状态，并对宫颈排毒及ＣＭＶ一ＩｇＭ阳性的母亲所生小孩进行临床追踪。结果显示：孕妇宫颈排毒率为４．５％，抗ＣＭＶ－ＩｇＧ和抗ＣＭＶ－ＩｇＭ阳性率分别为７７％和１３％，５９例脐血ＣＭＶ－ＩｇＭ阴性。宫颈排毒的３例其抗体检测抗ＣＭＶ－ＩｇＧ均阳性，抗ＣＭＶ－ＩｇＭ仅一例阳性。作者认为，对妊娠期活动性ＣＭＶ感染的诊断，仅检测抗ＣＭＶ－ＩｇＧ和抗ＣＭＶ－ＩｇＭ抗体滴度仍不足，尚须结合病毒分离和其它检测手段。