精液免疫抑制物质及其临床意义

近年来,随着免疫学的飞速发展,对机体的许多奥妙有了较多的了解。但迄今为止,还有一些难以理解的问题,生殖免疫中的某些现象即是一冽。如精子及精液都是高分子胶体蛋白质,在异体(雌体)中经子官腔上端的输卵管伞进入腹腔,理应刺激腹腔淋巴组织,引起免疫应答,甚至发生过敏反应,然而一般情况下并不发生。最近几年的生殖免疫研究资料揭示,精液中含有男性抑制物质(male inhibition material,MIM),随精子一起进入雌体生殖道,抑制了局部与全身免疫应答。不仅避免女性发生     

第7例 慢性肝病—顽固性腹水——胸水（Ⅱ）

一、临床分析1.早期肝硬化诊断明确 :本例患者为中年男性 ,起病缓慢 ,病情变化大 ,进行性加重。乙型肝炎病毒感染明确(ＨＢｓＡｂ、ＨＢｅＡｇ、ＨＢｃＡｂ阳性 ) ,反复ＡＬＴ升高 ,有乏力、纳差、恶心、厌油腻和肝病面容、肝掌、黄疸、低白蛋白血症、出凝血功能障碍等肝功能受损的表现 ,表明存在慢性乙型病毒性肝炎。在此基础上脾大、Ⅳ型胶原明显升高 ,提示肝炎后肝硬化的存在。但γ球蛋白不高 ,门脉不宽 ,血流速度正常 ,无腹壁静脉曲张和食管、胃底静脉曲张 ,无脾功能亢进 ,结合手术探查所见和综合分析 ,判定其肝硬化属早期。2 .早期肝硬…     

生长抑素对奥迪括约肌运动的作用机制

目的了解徨长抑素影响败类迪括约肌运动的神经通路成分。方法建立奥迪括约股测压慢性实验动物模型,研究Ｍ受体阻断剂、α受体阻断剂、β受体阻断剂、５－ＨＴ４受体阻断剂、一氧化氮合酶抑制剂和河豚毒素对生长抑素调节奥迪括约肌运动的影响。结果阿托品、二乙胺盐酸甲酯和河豚毒素阻断生长抑素对括约肌的兴奋作用;Ｌ－精氨酸甲酯阻断生长抑素对括约肌的抑制作用。结论生长抑素通过胆碱能和５－羟色胺神经元组成的兴奋性神经通路,     

急性心肌梗塞患者QT离散度与室性心律失常分级的关系及其 …

回顾性单盲法分析１０６例急性心肌梗塞患者入院后首次心电图,参照室律失常Ｌｏｗｎ和Ｗｏｆｆ分级分组,观察ＱＴ离散度与室性心律失常恶性程度的关系,探讨ＱＴｄ对ＡＭＩ患者预后的预测价值。认为ＱＴｄ值检测,对ＡＭＩ预后的预测具有一定的临床意义。     

急性心肌梗塞患者QT离散度与室性心律失常分级的关系及其临床意义

回顾性单盲法分析 10 6例急性心肌梗塞 (AMI)患者入院后首次心电图 ,参照室性心律失常Lown和Woff分级分组 ,观察QT离散度 (QTd)与室性心律失常恶性程度的关系 ,探讨QTd对AMI患者预后的预测价值。结果显示 ,QTd在AMI患者各亚组间和AMI组与正常对照组间差异均具有高度显著性 (P均 <0 0 1) ,且AMI组QTd与所发的室性心律失常恶性程度呈正相关 (rs’ =0 .5 73)。认为QTd值检测 ,对AMI预后的预测具有一定的临床意义     

Efficacy and Mechanism of Intravenous Sotalol for Termination of Paroxysmal Supraventricular Tachycardia

ＳＶＴ ,ｉｎｃｌｕｄｉｎｇＡＶＲＴａｎｄＡＶＮＲＴ ,ｉｓａｋｉｎｄｏｆａｒｒｈｙｔｈｍｉａｏｆｔｅｎｓｅｅｎｉｎｃｌｉｎｉｃａｌｐｒａｃ ｔｉｃｅ .Ｓｏｔａｌｏｌ,ａｃｌａｓｓⅢａｎｔｉ ａｒｒｈｙｔｈｍｉｃｄｒｕｇｗｉｔｈａｄｄｉｔｉｏｎａｌβ ｂｌｏｃｋｉｎｇａｇｅｎｔｐｒｏｐｅｒｔｉｅｓ ,ｈａｓｂｅｅｎｗｉｄｅｌｙｕｓｅｄｔｏｔｒｅａｔｖａｒｉｏｕｓａｒｒｈｙｔｈｍｉａ(ｓｕｐｒａ ｖｅｎｔｒｉｃｕｌａｒａｎｄｖｅｎｔｒｉｃｕｌａｒ)ｅｆｆｉｃｉｅｎｔｌｙｉｎｗｅｓｔｅｒｎｃｏｕｎｔｒｉｅｓ[1 9]…     

Retrospective Study on the Efficacy and Safety of Quinacrine Sterilization

Objective To observe and evaluate the efficacy and safety of quinacrine sterilization.Methods A total of 572 cases of quinacrine sterilization preformed during the 4 years from 1993to 1997in Jiangsu and Guizhou Provinces were employed in this study. The efficacy and safety of quinacrine sterilization in those case were studied and evaluated, with 588 cases of surgical sterilization performed at the same time being the control group.Results Both groups were with identical demographic and gynecological characteristics. The result of multiple decrement life table analysis showed the 12th gross cumulative failure rates for quinacrine sterilization was 3. 13% and serious side effects occurred in only 2 cases accounting for O. 35%. One was ectopic pregnancy (20 months after treatment). The other was due to anaphylaxis in 10 minutes after the second insertion). No difference in the liver and nephic functions was detected and no suspected cancer cells or cancer cells were found in the two groups. 99. 6% of the 572 women interviewed accepted the quinacrine sterilization.Conclusions Quinacrine sterilization method is with high acceptability but comparatively low effectiveness. It has been proved to be a safe method of contraception in short-term. However, the safety of long-term still needs further study.     

麦氏切口缝合的一点改进

我们自１９９８年４月始对经麦氏切口行化脓性阑尾炎阑尾切除术均实行腹膜外一层缝合,至１９９７年１２月共作３２３例,切口均一期愈合,效果满意,报告如下：１材料和方法全部化脓性阑尾炎病例不加选择,全部行麦氏切口腹膜外一层缝合。操作如下：（１）腹膜层用羊肠线...