针刺疣体加5-Fu注射液点涂治疗寻常疣110例

为寻找简便易行治疗寻常疣的方法,我科应用针刺疣体加五氟尿嘧啶注射液(5-Fu)局部点涂治疗寻常疣,并与YAG激光汽化疣体进行疗效对比观察,现报告如下。     

假性湿疣102例误诊分析

随着我国性传播疾病的增加 ,加上各种小广告对尖锐湿疣(CA)的非法宣传的误导 ,因此 ,一些诊所和医疗科室将外阴部的假性湿疣 (PCV)误诊为CV的病例时有发生。本文对我院 2 0 0 0～2 0 0 2年诊治并误诊为CA的 10 2例分析如下。1　临床资料1 1　一般资料　本组病例系皮肤科或由妇产科转入皮肤科的门诊病例。患者年龄 2 0～ 45岁 ,平均 2 9岁 ;已婚 91例 ,未婚 11例。有滴虫性阴道炎病史 7例 ,白带增多 5 9例 ,无症状 3 2例。1 2　皮损部位及特点　皮损均位于小阴唇内侧 ,10例同时波及阴道前庭及阴道口或尿道口。皮疹多表现为密集对称分布的…     

噻替派灌注治疗男性尿道内尖锐湿疣

临床资料　21例男性尖锐湿疣患者均有典型损害,并位于尿道舟状窝,多无自觉症状,少数有尿道刺痒感,均有尿流变形或呈喷状。8例作病检证实。随机分为治疗组(11例)及对照组(10例),两组条件相近。治疗方法　排尿后取截石位,常规消毒尿道外口及龟头,将锥形器(耳科窥器已消毒)轻轻插入舟状窝。治疗组灌注0.05%噻替派溶液5～8ml,对照组灌注1%病毒唑溶液5～8ml,随后紧夹尿道海绵体中部并使阴茎垂直于地面,防止药液外溢,保留20min。每周2次,连续8次后停止治疗,随访3个月作疗效判断,如治疗中疣体消退则停治疗。治疗前后分别查血、尿常规、肝功能,每次…     

咳喘平汤剂治疗慢性支气管炎临床及实验研究

运用自拟方咳喘平治疗急发期与慢迁期慢性支气管炎31例的临床与实验研究,并以古方清金化痰汤作为对照(31例)。结果:观察组控显率为67.74%,总有效率为93.55%;对照组控显率为41.94%,总有效率有74.19%,两组比较有显著性差异,P<0.05。动物实验结果提示,咳喘平具有较强的祛痰、镇咳、平喘和抑菌作用,与对照方比较差异非常显著,P<0.01。临床与实验的资料均证实,本方不失为治疗慢性支气管炎有效方剂。     

自血疗法治疗慢性荨麻疹35例

2001年，我们采用自血疗法治疗慢性荨麻疹35例，获得满意效果，总结报告如下。     

中国南方四省区流行的HIV-1 CRF01_AE病毒株基因特征研究

Objective To analyze the genetic characteristics of HIV-1 CRF01_AE strains prevailing in. the four provinces of southern China. Methods Plasma samples were collected from the newly diagnosed HIV-1 individuals reported in 2006 in Guangdong, Guangxi, Jiangxi and Hunan province. The gag and env gene fragments were amplified from RNA template extracted from plasma using RT and nested PCR methods. CRF01_AE sequences were analyzed by phylogcnetie methods and characterized by calculating the genetic distance and Entropy analysis. Results Two main epidemic clusters were found to exist in the CRF01 AE strains from 210 HIV-1 CRF01 AE infected individuals collected in the 4 provinces, southern China. It was found that no international reference strain was closely correlated with cluster Ⅰ , which including 123 samples. The strains in cluster Ⅱ, consisting 57 cases of samples, were closely related with the strains identified in Vietnam. Genetic distance analysis of gag and env genes showed that the diversity of cluster Ⅰ was obviously less than that of cluster Ⅱ. Data on nucleotide polymorphism showed that nucleotides compositions of 42 sites in gag and 40 sites in env wer esignificantly different between the two clusters. When compared with cluster Ⅱ , the polymorphism decreased at 61 nucleotide sites but increased at 21 sites in cluster Ⅰ. Conclusion This was the first report describing that two main epidemic clusters were existed in CRF01_AE strains prevailing in the 4 provinces, Southern China. The vires in cluster Ⅰ was the dominant strain in this region, with shorter period of circulation and higher proportion seen in the HIV-infected population, which might belong to CRF01_AE strain with certain features facilitating the spread of the virus. The virus in cluster Ⅱ was highly homology with the CRF01_AE strains from Vietnam, and seemed to have had several events of epidemics in populations in border regions of China and Vietnam.     

中国南方四省区流行的HIV-1 CRF01_AE病毒株基因特征研究

Objective To analyze the genetic characteristics of HIV-1 CRF01_AE strains prevailing in. the four provinces of southern China. Methods Plasma samples were collected from the newly diagnosed HIV-1 individuals reported in 2006 in Guangdong, Guangxi, Jiangxi and Hunan province. The gag and env gene fragments were amplified from RNA template extracted from plasma using RT and nested PCR methods. CRF01_AE sequences were analyzed by phylogcnetie methods and characterized by calculating the genetic distance and Entropy analysis. Results Two main epidemic clusters were found to exist in the CRF01 AE strains from 210 HIV-1 CRF01 AE infected individuals collected in the 4 provinces, southern China. It was found that no international reference strain was closely correlated with cluster Ⅰ , which including 123 samples. The strains in cluster Ⅱ, consisting 57 cases of samples, were closely related with the strains identified in Vietnam. Genetic distance analysis of gag and env genes showed that the diversity of cluster Ⅰ was obviously less than that of cluster Ⅱ. Data on nucleotide polymorphism showed that nucleotides compositions of 42 sites in gag and 40 sites in env wer esignificantly different between the two clusters. When compared with cluster Ⅱ , the polymorphism decreased at 61 nucleotide sites but increased at 21 sites in cluster Ⅰ. Conclusion This was the first report describing that two main epidemic clusters were existed in CRF01_AE strains prevailing in the 4 provinces, Southern China. The vires in cluster Ⅰ was the dominant strain in this region, with shorter period of circulation and higher proportion seen in the HIV-infected population, which might belong to CRF01_AE strain with certain features facilitating the spread of the virus. The virus in cluster Ⅱ was highly homology with the CRF01_AE strains from Vietnam, and seemed to have had several events of epidemics in populations in border regions of China and Vietnam.     

卡介菌多糖核酸与干扰素治疗尖锐湿疣的复发率比较

我们用卡介菌多糖核酸注射液（BCG－PSN）联合YAG激光、γ干扰素（IFN-γ）联合YAG激光对比治疗尖锐湿疣（CA）,观察其临床疗效、复发率和影响复发的因素,及 BCG－PSN对外周血Ｔ淋巴细胞及亚群的调节作用进行了初步探讨,现将结果报告如下……     

中国南方四省区流行的HIV-1 CRF01_AE病毒株基因特征研究

Objective To analyze the genetic characteristics of HIV-1 CRF01_AE strains prevailing in. the four provinces of southern China. Methods Plasma samples were collected from the newly diagnosed HIV-1 individuals reported in 2006 in Guangdong, Guangxi, Jiangxi and Hunan province. The gag and env gene fragments were amplified from RNA template extracted from plasma using RT and nested PCR methods. CRF01_AE sequences were analyzed by phylogcnetie methods and characterized by calculating the genetic distance and Entropy analysis. Results Two main epidemic clusters were found to exist in the CRF01 AE strains from 210 HIV-1 CRF01 AE infected individuals collected in the 4 provinces, southern China. It was found that no international reference strain was closely correlated with cluster Ⅰ , which including 123 samples. The strains in cluster Ⅱ, consisting 57 cases of samples, were closely related with the strains identified in Vietnam. Genetic distance analysis of gag and env genes showed that the diversity of cluster Ⅰ was obviously less than that of cluster Ⅱ. Data on nucleotide polymorphism showed that nucleotides compositions of 42 sites in gag and 40 sites in env wer esignificantly different between the two clusters. When compared with cluster Ⅱ , the polymorphism decreased at 61 nucleotide sites but increased at 21 sites in cluster Ⅰ. Conclusion This was the first report describing that two main epidemic clusters were existed in CRF01_AE strains prevailing in the 4 provinces, Southern China. The vires in cluster Ⅰ was the dominant strain in this region, with shorter period of circulation and higher proportion seen in the HIV-infected population, which might belong to CRF01_AE strain with certain features facilitating the spread of the virus. The virus in cluster Ⅱ was highly homology with the CRF01_AE strains from Vietnam, and seemed to have had several events of epidemics in populations in border regions of China and Vietnam.