Biomechanics of lumbosacral spinal fusion in combined compression-torsion loads

The current study investigates the stabilizing effects of three different types of spinal fusion to the juxta-free motion segments and to the fused segment of the lumbosacral spine under combined compression-torsion loads. Sixteen fresh human cadaver lumbosacral spines were tested under a simulated physiologic loading condition. The relative movements of the motion segments, as well as the angular rotations and the center of rotation were then computed and analyzed. The average torsional stiffness of the unfused three-motion segment was found to be 2.35 nm/degree. After fusion, the torsional stiffness did not increase significantly. Under the compression-torsional load, the anterior and bilateral-lateral fusions provided adequate stabilizing effect on the fused segment. The posterior fusion provided the least amount of stabilizing effect. These findings are similar to the results of the compression-bending experiment. Whereas the compression-bending loads produced significantly increased stress at the juxta-free segments, the compression-torsional loads did not produce any significant amount of increase in torsional stress at the juxta-free segments.     

电针加穴位注射治疗偏头痛28例

笔者在临床中以电针、穴位注射治疗偏头痛,取得较好的疗效,现介绍如下。一般资料本组病例共28例,其中男性6例,女性22例;年龄26~58岁,平均42岁;病程3~18年,平均10.5年。治疗方法电针加TDP照射:取穴:太阳、阳白透鱼腰、率谷透角孙、风池、合谷、列缺。辨证加减:有痰加丰隆、印堂;     

临床随访研究

目的探讨目前国内临床随访的情况。方法通过电子检索查阅中国期刊网历年文献。并对每篇文献进行从随访形式，随访时间，随访资料和主要指标进行总结。结论目前国内随访工作正在开展，但尚需统一管理及完善。     

高龄人群口腔卫生保健情况调查

目的：了解高龄老人口腔卫生保健状况.方法：对80岁以上老年人口腔卫生知识问卷调查.结果：具有口腔健康行为的人群,其口腔健康状况良好.结论：加强口腔卫生保健知识教育,养成良好口腔行为习惯,对促进老年人口腔健康很重要.     

瞄准前沿以人为本全面提升医院的综合竞争力

介绍了医院创新工作思路和瞄准国际前沿,高起点培训专业技术人才,全面提升医院综合竞争力的主要做法及取得的成效.     

胰岛素样生长因子-1受体在子宫内膜癌中的表达及临床意义

目的 研究子宫内膜癌组织中IGF-1R的分布、表达及其临床意义。方法 选取30例子宫内膜癌手术标本，石蜡切片，采用PV-600PicTureTM检测试剂进行免疫组化，测定IGF-1R的分布及表达，分析与临床病理之间的关系。另取10例正常的增生期子宫内膜标本作为对照。结果 IGF-1R为膜受体。IGF-1R在10例正常增生期子宫内膜细胞中的阳性表达率为70％，无过度表达；而在30例子宫内膜癌细胞中的阳性表达率为90％，过度表达率为40％（中度阳性7例、强阳性5例）。统计表明，正常增生期子宫内膜细胞与子宫内膜癌细胞相比IGF-1R阳性表达率差异尤显著性（P=0．13）；IGF-1R过度表达率差异有显著性（P=0．017）。子宫内膜癌细胞膜IGF-1R阳性表达及过度表达在高分化与中、低分化之间有显著差异（与分级呈负相关系：分化越低，IGF-1R的表达越强，反之，分化高，IGF-1R的表达则弱）。IGF-1R的阳性表达及过度表达在临床分期Ⅰ-Ⅲ期各组间均无明显差异。结论 IGF-1R在子宫内膜癌细胞膜表达，且随恶性程度的增加其表达量增加，IGF-1R的表达量可以预测内膜癌的预后，对临床治疗可能具有一定的指导意义。     

截瘫患者医院感染的监测及预防措施

目的了解截瘫患者医院感染的病原菌对药物敏感情况. 方法回顾分析我院自1996年9月～2003年11月,316例截瘫患者的有关临床资料. 结果 98例患者发生医院感染,医院感染率为31.01%,感染部位主要以呼吸道、皮肤软组织、手术切口、泌尿道感染为多;医院感染的病原菌主要是条件致病菌,以G-菌为主.结论医护人员必须严格无菌操作,根据细菌药敏结果合理选用抗菌药物,加强营养,提高患者机体抵抗力.     

瘦素对肝细胞三酰甘油沉积的影响

目的观察瘦素对人L-02脂肪变肝细胞三酰甘油(TG)沉积的影响,探讨瘦素在非乙醇性脂肪性肝病发生、发展中的作用。方法人肝L-02细胞培养接种于50 m l培养瓶中,用50%胎牛血清1640培养基造模,时间24 h。设立正常组、模型组、瘦素处理1,2,3组,处理组瘦素浓度分别为10-7mol/L,10-6mol/L,10-5mol/L,分别处理6 h;再以10-6mol/L浓度瘦素建立时效关系分别处理(6,12及24 h)。每组均行油红“O”染色观察脂肪化情况,高效液相色谱测细胞内TG含量变化。结果油红“O”染色显示50%的胎牛血清的1640培养基24 h能成功地制造肝细胞脂肪变性模型,加入瘦素处理后脂肪化程度减轻。高效液相色谱显示细胞内TG明显减少,且与瘦素呈剂量、时间依赖性关系。结论肝细胞脂肪变性时,瘦素能使肝细胞脂肪化程度减轻,能减少肝细胞TG的沉积,对脂肪肝防治有一定的作用。     

伊柔美白霜对家兔皮肤祛斑效果的观察

目的考察伊柔美白霜的祛斑功效。方法在家兔皮肤上涂抹补骨脂酊，待日光照射使皮肤上形成黄褐斑后，涂抹伊柔美白霜。结果涂抹伊柔美白霜20d后，黄褐斑有明显减退。结论伊柔美白霜具有脱色、增白的功效。     

The use of microimplants in orthodontic anchorage.

PURPOSE: Various types of temporary implants have been introduced to serve as orthodontic anchorage. The hypothesis of this study is that microimplants of 1.2 mm diameter can be used as orthodontic anchors, and that their success is related to their length. The aim of this study is to determine the incidence of anchor retention after orthodontic force application for moving teeth, and to determine the relationship of microimplant length to retention rate. METHODS: Fifty-nine microimplants (diameter: 1.2 mm) were placed in 29 patients as orthodontic anchorages. After 2 weeks of microimplant placement, a force of 100 to 200 g was loaded with an elastometric chain or NiTi coil spring. Risk factors were characterized as to why a microimplant may fail, and Fisher's exact test was used for statistical analysis. RESULTS: Nine microimplants were removed and the overall success rate was 84.7%. Exploring the causes for failure, we found significant differences between the length of microimplants and success rate; 6 mm was 72.2% and 8 mm was 90.2%. CONCLUSIONS: The results suggest that microimplants are suited as an alternative orthodontic anchorage. We recommend that 8-mm microimplants are preferable to 6-mm.