全文获取类型
收费全文 | 202篇 |
免费 | 6篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 1篇 |
妇产科学 | 2篇 |
基础医学 | 20篇 |
口腔科学 | 3篇 |
临床医学 | 13篇 |
内科学 | 37篇 |
皮肤病学 | 7篇 |
神经病学 | 7篇 |
特种医学 | 14篇 |
外科学 | 53篇 |
一般理论 | 1篇 |
预防医学 | 6篇 |
眼科学 | 8篇 |
药学 | 28篇 |
肿瘤学 | 9篇 |
出版年
2023年 | 2篇 |
2022年 | 3篇 |
2021年 | 18篇 |
2020年 | 2篇 |
2019年 | 5篇 |
2018年 | 8篇 |
2017年 | 3篇 |
2016年 | 1篇 |
2015年 | 4篇 |
2014年 | 6篇 |
2013年 | 5篇 |
2012年 | 17篇 |
2011年 | 18篇 |
2010年 | 11篇 |
2009年 | 11篇 |
2008年 | 10篇 |
2007年 | 7篇 |
2006年 | 15篇 |
2005年 | 24篇 |
2004年 | 9篇 |
2003年 | 15篇 |
2002年 | 7篇 |
2001年 | 1篇 |
1984年 | 1篇 |
1977年 | 1篇 |
1971年 | 1篇 |
1970年 | 1篇 |
1969年 | 1篇 |
1968年 | 1篇 |
1932年 | 1篇 |
排序方式: 共有209条查询结果,搜索用时 15 毫秒
101.
Badiu C Cristofor D Voicu D Coculescu M 《Revista medico-chirurgical?? a Societ????ii de Medici ??i Naturali??ti din Ia??i》2004,108(3):584-591
Porphyrias are metabolic disorders of heme biosynthesis, which encompass a broad range of symptoms and signs, neurologic, cutaneous or mixed. Because of lack of specificity and polymorphous clinical picture, porphyrias can mimic either neuropsychiatric, dermatologic, or gastrointestinal diseases. We present the case of a 58 years old man to whom clinical presentation suspicious of Addison's disease (melanoderma, fatigue, weight loss, intermittent abdominal pain) was the disguise of porphyria cutanea tarda. A general background of porphyrias and differential diagnosis with other forms of hepatic porphyria, as well as other causes of hyperpigmentation, are given. The clinician should be aware of the protean manifestations of porphyrias and include them in clinical judgment in various situations. 相似文献
102.
Venkataraman S Semelka RC Weeks S Braga L Vaidean G 《Journal of magnetic resonance imaging : JMRI》2003,17(1):43-53
PURPOSE: To evaluate magnetic resonance angiography (MRA) of the pelvis for the examination of the aorto-iliac system using arterial phase 3-D gradient echo and interstitial phase 2-D fat-suppressed spoiled gradient-echo (SGE), with comparison to surgery and angiography. MATERIALS AND METHODS: Ninety MR angiograms performed on 79 consecutive patients were analyzed, retrospectively, for the presence of narrowing, aneurysm, and dissection. Comparisons were made with angiography and surgery in 50 examinations, and a weighted kappa statistic test was applied to assess agreement. MR examinations were performed at 1.5T 3-D fast imaging in steady state precession (FISP) acquired immediately, and fat-suppressed SGE in the interstitial phase following gadolinium administration. RESULTS: MRA had overall sensitivities of 100% at aortic segments, 100% at common iliac, 93.8% at external, and 95.7% at internal iliac, and specificities of 100% at aortic segments, 89.7% at common iliac, 95.2% at external iliac, and 88.7% at internal iliac in detection of vascular disease. The agreement of MRA with the angiography and surgery yielded a weighted kappa statistic of 0.97 at the aortic, 0.94 at the common, 0.85 at the external, and 0.82 at the internal iliac segments. CONCLUSION: This study demonstrates an excellent performance of MRA in the evaluation of aorto-iliac arterial system and almost perfect agreement with angiography and surgery at all vascular levels. 相似文献
103.
Diaconu G Burlea M Grigore I Frasin M 《Revista medico-chirurgical?? a Societ????ii de Medici ??i Naturali??ti din Ia??i》2003,107(1):136-139
Epilepsy (E) is common in all types of cerebral palsy (CP) and in some varieties it is the rule. The aim of this study is to evaluate the nature, course and prognosis of seizures in patients with E and CP. Clinical observations were performed on a group of 109 patients, from 2.5 to 17 years of age, 2/3 associated mental retardation. The results proved that all types of seizures can be observed at the patients with CP and the epileptic attacks can be controlled in most cases with polytherapy. 相似文献
104.
Cafri C Fuchs S Slutzky O Weinstein JM Esanu G Ilia R 《The Journal of invasive cardiology》2003,15(5):285-288
Acute vessel closure complicates 0.5 9.3% of percutaneous coronary interventional procedures. This case series demonstrates the potential value of distal vessel angiographic visualization during abrupt vessel closure, which allows rapid determination of the underlying mechanism and the subsequent appropriate therapy. 相似文献
105.
Andersson Martin O. Marga Georgeta Banu Teofilia Dobler Gerhard Chitimia-Dobler Lidia 《Parasitology research》2018,117(5):1591-1597
Parasitology Research - Romania has a highly diverse tick fauna. Consequently, a high diversity of tick-transmitted pathogens might be a potential threat to humans. However, only a limited number... 相似文献
106.
Suspected pancreatic cancer: evaluation by dynamic gadolinium-enhanced 3D gradient-echo MRI 总被引:3,自引:0,他引:3
Birchard KR Semelka RC Hyslop WB Brown A Armao D Firat Z Vaidean G 《AJR. American journal of roentgenology》2005,185(3):700-703
OBJECTIVE: The objective of our study was to determine the sensitivity and specificity of gadolinium-enhanced 3D gradient-echo (GRE) MR images in the detection of pancreatic cancer. CONCLUSION: Dynamic gadolinium-enhanced 3D GRE images are both sensitive and specific in the detection of pancreatic cancer. Our study shows that the identification of pancreatic cancer using these images can be performed with a high degree of confidence and accuracy, making them very useful in the detection of pancreatic cancer. 相似文献
107.
108.
109.
Petrescu E Voicu PM Poiţelea M Stoica B Stănescu R Rusu M 《Revista medico-chirurgical?? a Societ????ii de Medici ??i Naturali??ti din Ia??i》2005,109(1):105-109
The aim of this study was to delete two genes from the genome of the fission yeast S. pombe in order to search for their functions in the cell. These genes are SPAC869.02c (MRI) and SPBC21C3.19 (MR2) and previous studies reported their significant induction after gamma irradiation. We carried out the deletions of the two genes and we replaced them with the selection marker ura4. Among the phenotype characteristics we tested the viability, the sexual behaviour and the radiosensitivity to ultraviolet and gamma irradiation. Our results indicate that MR1-deleted strain is sensitive to both UV and gamma irradiation, while the survival of the irradiated MR2-deleted strain doesn't appear to be influenced by the deletion. This suggests an involvement of MR1 gene in the adaptive response triggered by these types of genotoxic aggression. The comparison of MR1-d and MR2-d with the double deleted strains containing the deletion of MR1 or MR2 combined with the deletion of sty1 or rad3 genes led to a surprising result: the double mutants MR1-d sty1-d and MR1-d rad3-d were more resistant to both UV and gamma irradiation than the simple deleted strains sty1-d and rad3-d, respectively. This suggests a possible contribution of MR1 gene to the lethal process taking place in irradiated cells. 相似文献
110.
Billings SD Giblen G Fanburg-Smith JC 《The American journal of surgical pathology》2005,29(2):204-210
Low-grade fibromyxoid sarcoma (LGFMS), usually a deeply situated mass in adults, is uncommon in superficial soft tissue and in children. Nineteen superficial LGFMS from our files were studied for clinicopathologic features, the latter including tumor size, growth pattern, cellularity, collagen rosettes, vascularity, nuclear atypia, mitotic rate, necrosis, and immunophenotype. The patients included 12 males and 7 females who ranged in age from 2 to 70 years (mean, 29 years). There were 7 children. Tumor locations included the lower extremity (8), buttock (3), trunk (3), vulva/inguinal region (2), upper extremity (2), and unspecified subcutis (1). Clinical and histologic submitting diagnoses were mainly benign except for 3 cases, submitted as low-grade sarcoma, with only one as superficial LGFMS. The mean tumor size was 4.2 cm (range, 1.6-18 cm). Of 15 with evaluable resections, 5 had focal ink on tumor and 2 of these had known negative wider reexcisions. The tumors were relatively well circumscribed with low to moderate cellularity. The tumors alternated from myxoid zones with prominent curvilinear vasculature to collagenous fascicular zones. Collagen rosettes with peripheral round epithelioid cells and focal ischemic necrosis were present in 6 cases each. Mitotic rate was low (mean 1.6/50 HPF). Tumor cells were positive for vimentin and some were focally positive for actins, CD68, and EMA. CD34, keratins, and S-100 protein were negative. Follow-up (mean, 44 months; range, 10-84 months) on 16 patients demonstrated 14 with no evidence for disease, 2 with local recurrences at 5 and 16 months, but no metastases. Superficial LGFMS is more common than previously recognized and may affect children at a higher rate (7 of 19, 37%) than that for deep LGFMS. The prognosis is good and appears to be better than that for deep LGFMS. 相似文献