全文获取类型
收费全文 | 45461篇 |
免费 | 4347篇 |
国内免费 | 3548篇 |
专业分类
耳鼻咽喉 | 478篇 |
儿科学 | 472篇 |
妇产科学 | 388篇 |
基础医学 | 4737篇 |
口腔科学 | 748篇 |
临床医学 | 5832篇 |
内科学 | 5996篇 |
皮肤病学 | 480篇 |
神经病学 | 2128篇 |
特种医学 | 1581篇 |
外国民族医学 | 20篇 |
外科学 | 4493篇 |
综合类 | 9526篇 |
现状与发展 | 8篇 |
一般理论 | 2篇 |
预防医学 | 3458篇 |
眼科学 | 1095篇 |
药学 | 5226篇 |
55篇 | |
中国医学 | 3051篇 |
肿瘤学 | 3582篇 |
出版年
2024年 | 198篇 |
2023年 | 753篇 |
2022年 | 1935篇 |
2021年 | 2387篇 |
2020年 | 1879篇 |
2019年 | 1438篇 |
2018年 | 1464篇 |
2017年 | 1559篇 |
2016年 | 1332篇 |
2015年 | 2144篇 |
2014年 | 2643篇 |
2013年 | 2531篇 |
2012年 | 3613篇 |
2011年 | 3742篇 |
2010年 | 2703篇 |
2009年 | 2031篇 |
2008年 | 2480篇 |
2007年 | 2455篇 |
2006年 | 2318篇 |
2005年 | 2045篇 |
2004年 | 1615篇 |
2003年 | 1661篇 |
2002年 | 1574篇 |
2001年 | 1245篇 |
2000年 | 1052篇 |
1999年 | 955篇 |
1998年 | 568篇 |
1997年 | 507篇 |
1996年 | 393篇 |
1995年 | 373篇 |
1994年 | 344篇 |
1993年 | 177篇 |
1992年 | 217篇 |
1991年 | 213篇 |
1990年 | 143篇 |
1989年 | 138篇 |
1988年 | 117篇 |
1987年 | 118篇 |
1986年 | 95篇 |
1985年 | 61篇 |
1984年 | 46篇 |
1983年 | 33篇 |
1982年 | 24篇 |
1981年 | 13篇 |
1980年 | 10篇 |
1979年 | 14篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
991.
为了探讨Id4基因的反义核酸对人红白血病K5 62细胞增生的作用 ,用DNA重组技术将人反义Id4基因插入到真核表达载体pXJ41 neo上 ,重组质粒和空载体分别转染K5 62细胞 ,得到 pAId4和 pK5 62 (对照 )克隆细胞株。发现 :pAId4的生长受到抑制 ,倍增时间加长。免疫印迹实验分析相关蛋白的表达 ,其中CDK4和CyclinD1在 pAId4细胞中的表达量均低于对照细胞 pK5 62 ,而RB蛋白在 pAId4细胞中的表达量高于对照细胞pK5 62 ,揭示了反义Id4引起细胞出现生长抑制的可能机制 ,并探讨了Id4基因对人红白血病K5 62细胞增生的具体作用。研究结果对造血干细胞的体外扩增、分化及红白血病的基因治疗均有重要的参考价值。 相似文献
992.
Shuai Yuan Cheng Fang Wei-Dong Leng Lan Wu Bing-Hui Li Xing-Huan Wang Hailiang Hu Xian-Tao Zeng 《军事医学研究(英文)》2021,8(4):564-578
Periodontitis has been proposed as a novel risk factor of genitourinary cancers:although periodontitis and genitourinary cancers are two totally distinct types ... 相似文献
993.
目的 探讨侵袭性肺曲霉病(IPA)的临床特征、实验室检查及预后风险因素。方法 回顾性分析2020年9月—2023年6月某院IPA患者的临床资料,分析其临床特征及预后风险因素。结果 共纳入111例IPA患者,年龄为(68.8±12.5)岁,以男性为主(63.1%),主要分布于呼吸科、重症监护病房(ICU)、血液科及感染科,共占75.6%。IPA常见的曲霉为烟曲霉、黄曲霉及黑曲霉,分别占67.6%、19.8%、4.5%。支气管肺泡灌洗液的(1,3)-β-D-葡聚糖抗原检测(G试验)、半乳甘露聚糖抗原检测(GM试验)阳性率分别为73.7%、68.0%。111例IPA患者中,32例(28.8%)随访发现预后不良,25例(22.5%)合并病毒感染。logistic多因素回归分析显示,合并病毒感染[OR(95%CI):4.535(1.385~14.846),P=0.012]、连续3周使用糖皮质激素史[OR(95%CI):9.128(2.293~36.341),P=0.002]、机械通气[OR(95%CI):4.690(1.100~19.990),P=0.037]及留置导尿管[OR(95%CI):7... 相似文献
994.
995.
996.
Shang-Ling Wu Long-Yun Peng Yu-Ming Chen Fang-Fang Zeng Shu-Yu Zhuo Yan-Bing Li Wei Lu Pei-Yan Chen Yan-Bin Ye 《Nutrients》2022,14(9)
The evidence regarding the impact of the scores on healthy eating indices on the risk of cardiovascular events among patients with type 2 diabetes (T2D) is limited. As such, in this study, we examined the associations of adherence to the Chinese and American dietary guidelines and the risk of cardiovascular disease (CVD) among Chinese individuals with T2D. We conducted a 1:1 age- and sex-matched case–control study based on a Chinese population. We used a structured questionnaire and a validated 79-item food-frequency questionnaire to collect general information and dietary intake information, and calculated the Chinese Healthy Eating Index (CHEI) and the Healthy Eating Index-2015 (HEI-2015). As participants, we enrolled a total of 419 pairs of hospital-based CVD cases and controls, all of whom had T2D. We found a significant inverse association between diet quality scores on the CHEI and HEI-2015 and the risk of CVD. The adjusted odds ratios (95% confidence interval) per five-score increment were 0.68 (0.61, 0.76) in the CHEI and 0.60 (0.52, 0.70) in the HEI-2015. In stratified analyses, the protective associations remained significant in the subgroups of sex, BMI, smoking status, tea-drinking, hypertension state, dyslipidemia state, T2D duration, and medical nutrition therapy knowledge (all p < 0.05). These findings suggest that a higher CHEI or HEI-2015 score, representing a higher-quality diet relative to the most recent Chinese or American dietary guidelines, was associated with a decreased risk of CVD among Chinese patients with T2D. 相似文献
997.
Magnetic domain motion has been widely studied in the fields of spintronics, nanowires, and thin films. However, there is a lack of such studies on industrial steels, especially for domain motion under the action of varying stress. Understanding domain motion under stress is helpful for the improvement of evaluation accuracy and the establishment of theoretical models of passive, nondestructive testing technology. This paper presents the influence of varying tensile stresses on the magnetic domain motion of silicon steel sheets. Magnetic domain rotation and domain wall displacement were characterized using magnetic domain images, and their motion mechanisms under elastic and plastic stresses are presented. The results show that the domain rotation under stress involves reversible and irreversible changes. The effect of material rearrangement on domain rotation and domain wall displacement after plastic deformation is discussed. Based on the motion mechanism, a threshold stress value (TSV) required for the complete disappearance of the supplementary domains in the elastic range is proposed, enabling the classification of the elastic stress ranges in which the reversible and irreversible domain rotations occur. In addition, the effect of microstructure on TSV is also discussed, and the results show that the regions far away from the grain boundary need larger stresses to complete an irreversible domain rotation. Additionally, the domain width and orientation also affect the TSV. These findings regarding the domain motion mechanism and TSV can help to explain the sequence of domain rotation under stress and modify the stress assessment under dynamic loads in electromagnetic nondestructive evaluation, especially in the magnetic memory method. 相似文献
998.
Haochen Liu Xuehan Bai Zhen Li Lin Fan Junlei Tang Bing Lin Yingying Wang Mingxian Sun 《Materials》2022,15(9)
Titanium alloys have high specific strength and excellent corrosion resistance and have been applied in deep-sea engineering fields. However, stress corrosion cracking may become one of the biggest threats to the service safety of a high-strength titanium alloy, as well as its weldment. In this work, stress corrosion cracking of a gas-tungsten-arc-welded Ti-6Al-3Nb-2Zr-1Mo (Ti6321) alloy influenced by the applied potentials in simulated deep-sea and shallow-sea environments was investigated by combining slow strain rate testing with electrochemical measurements. The results showed that the service environment and applied potential have a substantial effect on the stress corrosion cracking behavior of the Ti6321 welded joint. The Ti6321 welded joint exhibited higher stress corrosion susceptibility in a simulated deep-sea environment and at a strong polarization level owing to the diminishing protection of the passive film under passivation inhibition and the enhancement of the hydrogen effect. The fracture of a Ti6321 welded joint in the weld material could be attributed to the softening effect of the thick secondary α within the coarse-grained martensite. The electrochemical evaluation model of stress corrosion cracking susceptibility of a Ti6321 welded joint in a simulated marine environment was established by adding the criterion in the passivation region based on the literature model, and four potential regions corresponding to different stress corrosion cracking mechanisms were classified and discussed. Our study provides useful guidance for the deep-sea engineering applications of Ti6321 alloys and a rapid assessment method of stress corrosion risk. 相似文献
999.
1000.
目的:研究老年患者胸腔镜肺叶切除术(video-assisted thoracic surgery, VATS)前行胸椎旁神经阻滞(paravertebral nerve block, PVB)所需罗哌卡因的最佳药物浓度。方法:选取南京医科大学附属淮安第一医院2019年1月至2019年12月于全身麻醉下行VATS的老年... 相似文献