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Hee Sup Shin Chang-Woo Ryu Jun Seok Koh Seung Hwan Lee 《Interventional neuroradiology》2014,20(4):418-423
995.
Kathleen Fisher FNP‐BC DNP RN Suha Al‐Oballi Kridli PhD RN 《International journal of nursing practice》2014,20(3):327-335
The study investigated the relationship between motivation, self‐efficacy and demographic variables, and determined if they affect the performance of health promotion behaviours in overweight or obese middle‐aged American women. The sample consisted of middle‐aged American women from a small town in Michigan. Two groups of women aged 30–65, one with a body mass index (BMI) range of 25–29, and the second with a BMI of ≥ 30, completed the Health Self‐Determinism Index, the General Self‐Efficacy Scale and the Health Promoting Lifestyle Profile‐II. Self‐efficacy was found to be a significant predictor in the performance of health‐promoting behaviours in both the overweight and obese participants in this study. Motivation was not found to be a significant predictor of performance of health promotion behaviours in either participant group. Education was found to be a significant predictor of performance of health promotion behaviours in the obese participants only. Nurses need to develop effective methods of supporting self‐efficacy in both the overweight and obese middle‐aged American women. Nursing‐based research focusing on interventions to improve self‐efficacy, as well as studies identifying effective educational techniques to improve the practice of health promotion behaviours in this population is necessary. Further investigation into the effect of motivation and demographics on the performance of health promotion behaviours is also needed. 相似文献
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Negative correlation between the change in bone mineral density and serum osteocalcin in patients with hyperthyroidism 总被引:9,自引:0,他引:9
M S Lee S Y Kim M C Lee B Y Cho H K Lee C S Koh H K Min 《The Journal of clinical endocrinology and metabolism》1990,70(3):766-770
To assess the changes in bone mineral density and osteoblastic activity in patients with hyperthyroidism and to investigate the relationship between those changes, we measured bone mineral density and serum osteocalcin in 109 patients with Graves' disease, comprising 75 untreated patients and 34 patients under treatment, and 200 normal controls. The degree of change in bone mineral density was quantified with Z transformation, in which we used means and SDs of bone mineral densities obtained in the process of age- and sex-matched 1:1 pairing developed by ourselves. Bone mineral density was low in female patients with hyperthyroidism in the spine, femur neck, trochanter, and Ward's triangle, but was not low in male patients. Serum osteocalcin was elevated in patients with untreated Graves' disease and correlated negatively with the Z values of bone mineral densities of the spine, femur neck, and trochanter. In conclusion, indices of osteoblastic activity were elevated in patients with hyperthyroidism, probably secondary to a thyroid hormone-induced increase in bone resorption which resulted in reduced bone mineral density. Quantification of the change in bone mineral density by using the parameters derived in the process of age- and sex-matched pairing seems to be an efficient method for statistical analyses. 相似文献
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K Jeon W J Koh O J Kwon G Y Suh M P Chung H Kim N Y Lee Y K Park G H Bai 《The international journal of tuberculosis and lung disease》2005,9(9):1046-1051
OBJECTIVE: To investigate the recovery rate of non-tuberculous mycobacteria (NTM) from acid-fast bacilli (AFB) smear-positive sputum specimens at a tertiary care medical centre in South Korea with a high pulmonary tuberculosis (PTB) burden. DESIGN: Retrospective analysis of data from AFB smear- and culture-positive sputum specimens collected between January 1998 and December 2001. RESULTS: Over 4 years, 1328 sputum specimens collected from 616 patients were AFB smear- and culture-positive. NTM were recovered from 9.1% (121/1328) of the smear-positive sputum specimens, and from 8.1% (50/616) of patients with smear-positive sputum. NTM were isolated at least twice in 94% (47/50) of the patients from whom NTM was recovered. The most common organism found was Mycobacterium avium complex, followed by M. abscessus. CONCLUSION: These results suggest that a substantial proportion of patients at a tertiary care medical centre in South Korea with AFB smear-positive sputum specimens may have NTM lung disease rather than PTB. 相似文献
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Lee KU Lee IK Han J Song DK Kim YM Song HS Kim HS Lee WJ Koh EH Song KH Han SM Kim MS Park IS Park JY 《Circulation research》2005,96(11):1200-1207
Increased oxidative stress in vascular cells plays a key role in the development of endothelial dysfunction and atherosclerosis. Uncoupling protein 2 (UCP2) is an important regulator of intracellular reactive oxygen species (ROS) production. This study was undertaken to test the hypothesis that, UCP2 functions as an inhibitor of the atherosclerotic process in endothelial cells. Adenovirus-mediated UCP2 (Ad-UCP2) overexpression led to a significant increase in endothelial nitric oxide synthase (eNOS) and decrease in endothelin-1 mRNA expression in human aortic endothelial cells (HAECs). Moreover, UCP2 inhibited the increase in ROS production and NF-kappaB activation, and apoptosis of HAECs induced by lysophophatidylcholine (LPC) and linoleic acid. LPC and linoleic acid caused mitochondrial calcium accumulation and transient mitochondrial membrane hyperpolarization, which was followed by depolarization. UCP2 overexpression prevented these processes. In isolated rat aorta, Ad-UCP2 infection markedly improved impaired vascular relaxation induced by LPC. The data collectively suggest that UCP2, functions as a physiologic regulator of ROS generation in endothelial cells. Thus, measures to increase UCP2 expression in vascular endothelial cells may aid in preventing the development and progression of atherosclerosis in patients with metabolic syndrome. 相似文献
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