全文获取类型
收费全文 | 895篇 |
免费 | 172篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 48篇 |
妇产科学 | 12篇 |
基础医学 | 68篇 |
口腔科学 | 10篇 |
临床医学 | 151篇 |
内科学 | 224篇 |
皮肤病学 | 30篇 |
神经病学 | 45篇 |
特种医学 | 78篇 |
外科学 | 172篇 |
综合类 | 59篇 |
现状与发展 | 20篇 |
预防医学 | 60篇 |
眼科学 | 25篇 |
药学 | 20篇 |
中国医学 | 2篇 |
肿瘤学 | 48篇 |
出版年
2024年 | 6篇 |
2023年 | 42篇 |
2021年 | 17篇 |
2020年 | 22篇 |
2019年 | 10篇 |
2018年 | 51篇 |
2017年 | 46篇 |
2016年 | 32篇 |
2015年 | 43篇 |
2014年 | 46篇 |
2013年 | 58篇 |
2012年 | 23篇 |
2011年 | 30篇 |
2010年 | 52篇 |
2009年 | 62篇 |
2008年 | 31篇 |
2007年 | 23篇 |
2006年 | 29篇 |
2005年 | 14篇 |
2004年 | 12篇 |
2003年 | 14篇 |
2002年 | 16篇 |
2001年 | 19篇 |
2000年 | 11篇 |
1999年 | 18篇 |
1998年 | 30篇 |
1997年 | 32篇 |
1996年 | 43篇 |
1995年 | 29篇 |
1994年 | 17篇 |
1993年 | 21篇 |
1992年 | 7篇 |
1991年 | 9篇 |
1990年 | 10篇 |
1989年 | 13篇 |
1988年 | 15篇 |
1987年 | 14篇 |
1986年 | 13篇 |
1985年 | 12篇 |
1984年 | 6篇 |
1983年 | 6篇 |
1982年 | 8篇 |
1981年 | 4篇 |
1980年 | 5篇 |
1978年 | 12篇 |
1977年 | 8篇 |
1976年 | 7篇 |
1975年 | 5篇 |
1964年 | 5篇 |
1963年 | 4篇 |
排序方式: 共有1084条查询结果,搜索用时 328 毫秒
991.
Storb R; Raff RF; Appelbaum FR; Schuening FW; Sandmaier BM; Graham TC; Thomas ED 《Blood》1988,72(4):1300-1304
In view of reported attempts at marrow grafting after nuclear accidents with a broad range of radiation exposures, the present study explored the total-body irradiation (TBI) conditions needed for engraftment in a canine model by using marrow from DLA-identical littermates. Previous studies have shown that such grafts are consistently successful when recipients are exposed to 920 cGy of TBI delivered at a rate of 7 cGy/min from opposing dual cobalt sources. The present TBI doses were all in the lethal range. Five dogs were administered 450 cGy; seven dogs, 600 cGy; five dogs, 700 cGy; and five dogs, 800 cGy of TBI administered at 7 cGy/min. They received a median of 3.3 x 10(8) marrow cells/kg intravenously after completion of radiation. Results showed transient allogeneic marrow engraftment in all dogs administered the lowest dose of TBI studied (450 cGy). Importantly, transient grafts permitted four of five dogs to live long enough for autologous marrow recovery to occur. At increasing radiation doses, 600, 700, and 800 cGy, the risk of graft failure lessened, with 3 of 7, 2 of 5, and 1 of 5 dogs, respectively, showing graft rejection. Fewer dogs survived with autologous marrow recovery, and more showed sustained allogeneic engraftment (4 of 7, 3 of 5, and 4 of 5 dogs, respectively). We conclude that DLA-identical littermate marrow grafts are beneficial in the setting of otherwise lethal radiation exposures, with most dogs either experiencing sustained allogeneic engraftment or surviving with autologous marrow recovery due to the extended support provided by a transient allogeneic graft. 相似文献
992.
Twenty-six patients with pericardial constriction confirmed by catheterization were studied by dynamic computed tomography (CT). The posterolateral wall of the left ventricular myocardium was not detected in five patients (19.2%). None had evidence of previous myocardial infarction on electrocardiogram or levocardiogram. In 16 patients, a pericardiectomy was performed to remove pericardial constriction. All five patients with nondetectable posterolateral walls of the left ventricle died at or immediately following surgery because of acute myocardial failure. Nonvisualization of the posterolateral wall of the left ventricle in patients with constrictive pericarditis suggests the presence of myocardial fibrosis or atrophy. Surgery is an extremely high risk in these patients. 相似文献
993.
994.
Physiological insights gained in the 1980s into mechanisms of disease progression in experimental chronic nephropathies established the basis for therapeutic interventions to retard the progression of chronic renal disease in humans. In the 1990s, several large-scale clinical trials have confirmed the renoprotective effects of angiotensin-converting enzyme inhibitors in diabetic and nondiabetic nephropathies. Other studies have afforded strong support for the efficacy of dietary protein restriction in certain settings and underscored the importance of blood pressure control in proteinuric individuals. These interventions form the core of current strategies designed to preserve kidney function in patients with chronic renal disease. 相似文献
995.
996.
997.
Murray Esler MBBS PhD Graeme Eisenhofer PhD Jaye Chin PhD Garry Jennings MD BS Ian Meredith BSc MBBS Helen Cox BSc Gavin Lambert BSc Jane Thompson MBBS Anthony Dart BA DPhil BM BCh 《Clinical autonomic research》1991,1(2):103-108
Radiotracer methods were used to measure the rates of regional release of adrenaline and noradrenaline into plasma in man. This was done as a partial test of a theory of essential hypertension pathogenesis which envisages an important cotransmitter function for neuronally released adrenaline. In healthy resting men no release of adrenaline could be detected from the heart, lungs or liver. Adrenaline was released into the right renal vein but an adrenal medullary source is suspected. With the relatively limited activation of the cardiac sympathetic outflow which accompanied mental challenge and isometric exercise, cardiac adrenaline release remained undetectable. During supine bicycle exercise, which increased cardiac noradrenaline release 10–30 fold, to a mean value of 197ng/min, cardiac adrenaline release averaged 2.36 ng/min. In two clinical conditions associated with persistently elevated plasma adrenaline concentrations, cardiac failure and adrenaline-secreting phaeochromocytoma, regional release of adrenaline was clearly evident. Thus, in normal man during exercise, and in patients with cardiac failure at rest, adrenaline is released from non-adrenal sources, and probably from sympathetic nerves. Whether neuronal adrenaline release of the degree found would be sufficient to facilitate noradrenaline release, augment sympathetically-mediated cardiovascular responses and contribute to the development of arterial hypertension remains to be tested. 相似文献
998.
999.
Cardiac dysrhythmias during oral surgery. Comparison of hyoscine and droperidol premedication 总被引:1,自引:0,他引:1
The incidence of cardiac dysrhythmias during inpatient dental anaesthesia under halothane was studied following either hyoscine or droperidol as a supplement to papaveretum for premedication. Forty-three percent of patients given hyoscine exhibited cardiac dysrhythmias compared to 23 percent of the group given droperidol (p = 0.03). The incidence of dysrhythmias bore no relationship to the age, sex or weight of the patient, nor to the end tidal carbon dioxide tension. 相似文献
1000.