甘肃地区汉族和回族脑出血患者α-内收蛋白基因rs4963多态性分析

目的 分析甘肃地区汉族和回族脑出血患者α-内收蛋白基因rs4963多态性的分布情况。方法 对甘肃地区汉族和回族脑出血患者各176例应用血液基因组DNA提取试剂盒方法检测α-内收蛋白基因rs4963多态性,比较rs4963多态性的分布差异。结果 汉族组和回族组α-内收蛋白基因rs4963基因型分布、等位基因频率均无明显差异(P>0.05); 按性别分层后汉族组与回族组基因型分布和等位基因频率仍均无明显差异(P>0.05)。结论 α-内收蛋白基因rs4963多态性在甘肃地区汉族和回族脑出血人群中无民族差异。     

肠梗阻的CT诊断

目的:探讨CT诊断肠梗阻的价值。方法:回顾性分析经手术或临床证实51例肠梗阻患者的CT资料。结果:CT对梗阻病因诊断准确46例(90.2%);对梗阻部位诊断准确49例(96.1%);诊断绞窄性肠梗阻9例(100%)。结论:CT检查可判断肠梗阻,确定肠梗阻的原因、部位以及性质,是肠梗阻检查的最佳方法。     

胃间质瘤的CT诊断

胃肠道间质瘤（ Gastrointestinal stromal tumors, GIST）是常见的胃肠道间叶性肿瘤,起源于胃肠道、大网膜及肠系膜的KIT（CD117干细胞因子受体）染色阳性的梭形细胞或上皮样细胞的间质肿瘤。最常发生于胃（约60％～70％）,占胃部肿瘤的1％-3％。     

维生素A防治小儿反复呼吸道感染的疗效观察

目的 探讨维生素A治疗反复呼吸道感染(RRTI)的临床与免疫抗体变化.方法 随机选择反复呼吸道感染患儿204例,对照组100例,给予一般抗炎及对症处理,观察组在一般治疗基础上加用维生素A,比较两组患儿治疗后的临床疗效,同时检测治疗前后免疫抗体的变化.结果 维生素A观察组显效率、总有效率均明显高于对照组,差异有显著性(P＜005).维生素A治疗后较治疗前IgA及IgG均明显升高,与对照组比较差异有显著性(P＜005).结论 维生素A可通过增强细胞和体液免疫功能,阻止淋巴细胞过度凋亡来提高治疗小儿RRTI临床疗.     

Clinical analysis of stage Ⅰ and Ⅱ cervical carcinoma in elderly women

Objective To explore the characteristics, related risk factors and prognosis of cervical carcinoma in elderly women. Methods 163 cases with stage Ⅰ-Ⅱ cervical carcinoma according to International Federation of Gynecology and Obstetrics (FIGO) criteria underwent radical hysterectomy and pelvic lymph dissection from January 1997 to December 2006. They were divided into aged group, adult group and young group. The clinical pathological data, prognosis and recurrence were retrospectively analyzed. Results The prevalence rate of stage Ⅱ cervical carcinoma was 78.7% (37/47) in aged group, 61.7 % (58/94) in adult group and 59.1% (13/22) in young group. The prevalence difference was statically significant. The prevalence rate of non-squamous cell carcinoma was 8. 5 % (4/47) in aged group, which was higher than that in adult group [5.3%(5/94)]and lower than that in young group [18. 2% (4/22)] (P<0.05). In aged group, pathological grading were 78.7% (37/47) of middle differentiation and 4. 3% (2/47) of low differentiation(P<0. 01). The rate of lymph node metastasis was 8. 51% (4/47)in aged women, 27.7 % (26/94) in adult women and 40.90% (9/22) in young women (P<0. 01). The recurrence rate was similar among the three groups. The death rate was 85.7% in overall recurrent cases, (12/14)in aged group, 73.1% (19/26)in adult group and 50.0% (4/8)in young group, and there was no significant difference (P=0. 193). Conclusions Cervical carcinoma in elderly women has a later clinical stage, higher prevalence of non-squamous cell carcinoma, more middle differentiation tumour tissues and fewer lymphatic metastasis, which can provide evidence for clinical diagnosis and treatment.     

Clinical analysis of stage Ⅰ and Ⅱ cervical carcinoma in elderly women

Objective To explore the characteristics, related risk factors and prognosis of cervical carcinoma in elderly women. Methods 163 cases with stage Ⅰ-Ⅱ cervical carcinoma according to International Federation of Gynecology and Obstetrics (FIGO) criteria underwent radical hysterectomy and pelvic lymph dissection from January 1997 to December 2006. They were divided into aged group, adult group and young group. The clinical pathological data, prognosis and recurrence were retrospectively analyzed. Results The prevalence rate of stage Ⅱ cervical carcinoma was 78.7% (37/47) in aged group, 61.7 % (58/94) in adult group and 59.1% (13/22) in young group. The prevalence difference was statically significant. The prevalence rate of non-squamous cell carcinoma was 8. 5 % (4/47) in aged group, which was higher than that in adult group [5.3%(5/94)]and lower than that in young group [18. 2% (4/22)] (P<0.05). In aged group, pathological grading were 78.7% (37/47) of middle differentiation and 4. 3% (2/47) of low differentiation(P<0. 01). The rate of lymph node metastasis was 8. 51% (4/47)in aged women, 27.7 % (26/94) in adult women and 40.90% (9/22) in young women (P<0. 01). The recurrence rate was similar among the three groups. The death rate was 85.7% in overall recurrent cases, (12/14)in aged group, 73.1% (19/26)in adult group and 50.0% (4/8)in young group, and there was no significant difference (P=0. 193). Conclusions Cervical carcinoma in elderly women has a later clinical stage, higher prevalence of non-squamous cell carcinoma, more middle differentiation tumour tissues and fewer lymphatic metastasis, which can provide evidence for clinical diagnosis and treatment.     

64排螺旋CT血管成像胸痛三联检查智能触发阈值的合理选择

目的探讨不同智能触发阈值对64排螺旋CT一次性心胸联合检查同时显示肺动脉、主动脉及冠状动脉成像质量的影响。方法 120例患者随机分成4组,分别按触发阈值70 HU(A)、90 HU(B)、110HU(C)、130 HU(D)启动扫描,行64排螺旋CT胸部动脉成像,在心电门控下一次性完成主动脉、肺动脉及冠状动脉扫描,比较各组间肺动脉、主动脉强化CT值,同时比较四组间肺动脉和冠状动脉成像质量的差别。结果肺动脉强化CT值及图像质量各组间均有统计学意义(F=266.443,χ2=78.89,P=0.000),A组平均CT值最高,成像质量较好,D组平均CT值较低,成像质量较差;主动脉平均强化CT值A组较低,四组间差异有统计学意义(F=24.14,P=0.000),B、C、D三组间差异无统计学意义(P>0.05);冠状动脉成像质量四组间差异有统计学意义(χ2=79.70,P=0.000),C组成像质量最好,A组较差。结论不同触发阈值对64排螺旋CT胸部动脉三联检查成像质量有一定的影响,当触发阈值为90¹10 HU时可以同时获得主动脉、肺动脉及冠状动脉的较为理想的图像以满足临床诊断需要。     

正畸治疗中牙周健康维护的临床观察

目的观察口腔健康教育和牙周洁治对正畸患者牙周健康维护的影响.方法选择固定正畸患者60例,随机分为2组,观察组接受口腔健康教育,正畸治疗6月全口洁治一次.对照组不采取任何措施.分别于治疗后4月、8月检查口腔卫生指数(OHI-S)、牙龈指数(GI)并进行分析.结果观察组牙周健康指数明显低于对照组.结论正畸治疗可致牙周组织损害,口腔健康教育和牙周洁治是正畸治疗中牙周健康维护的有效方法.     

北京市2000～2004年妊娠糖尿病文献统计分析

以CBMdisc及CMCI为检索工具，探讨北京市近5年的妊娠糖尿病的研究现状与发展趋势，揭示一些医疗机构的治疗水平、相关的核心作者、研究焦点等，得出一些启示供大家参考。