益母草防治初发期急性肾小管坏死的实验研究

ＳＤ成年雄性大鼠，禁止１６小时，肌注甘油引起急性肾小管坏死（ＡＴＮ），于其初发期给予不同药液，观察到益母草组３、２４及４８小时Ｂｃｒ升高值，２４及４８小时ＢＵＮ升高值均明显低于自来水组和单纯禁水组，而与校正对照异搏停组近似，肾组织损伤程度亦明显减轻。结果表明，益母草对初发期急性肾小管坏死（ＩＡＴＮ）有一定的防治作用。     

还原型谷胱甘肽治疗慢性乙型肝炎疗效观察

2002年10月-2003年9月,我院应用还原型谷光甘肽(古拉定)治疗慢性乙型肝炎90例,取得良好疗效,总结如下。资料与方法 一、病例选择 180例慢性乙型肝炎为我院住院病患者,诊断符合2000年9月中华医学会传染病与寄生虫病学分会和肝病学分会修订的诊断标准。随机分     

珠子参挥发油的化学成份

利用气相色谱—质谱—计算机联用仪分析了云南省腾冲县产珠子参挥发油的成份,从中鉴定了27种化合物,测定了它们的相对含量,其中有10种倍半萜烯和一种倍半萜醇。     

口内入路小型接骨板在下颌骨骨折治疗中的应用42例

1999年 5月至 2 0 0 2年 3月 ,作者对 4 2例下颌骨骨折患者采用口内入路小型接骨板坚强内固定治疗 ,报道如下。1　临床资料1.1　一般资料　本科近 3a来下颌骨新鲜骨折 (除外髁突髁颈及下颌升支骨折 )行口内入路小型接骨板坚强内固定治疗者 4 2例 ,共 4 8处。其中男 34例 ,女 8例 ,年龄 18～ 4 3岁 ,平均 2 9岁。颏孔前区单线骨折 18例 (18处 )、双线骨折 6例(6处 ) ,下颌体骨折 4例 (4处 ) ,下颌角骨折 8例 (8处 ) ,颏部和下颌角联合骨折 6例 (12处 )。 2 6例为开放性骨折 ,16例为闭合性骨折 ;骨折线上有牙齿存在者 19例 ,其中 8例为阻生齿…     

单纯病例研究方法在流行病学研究中的应用

流行病学在公共卫生决策与计划、预防疾病和促进健康方面正在发挥着愈来愈重要的作用。分子流行病学研究的兴起为揭开疾病的“黑匣子”之谜创造了条件 ,为阐明致病因素与发病机制提供了有利的工具 ,与此同时也促进了该领域方法学的研究 ,并取得了令人瞩目的进展。其中 ,单纯病例研究 (case onlystudy)方法在探索环境 基因交互作用、评价环境暴露和生物效应以及寻找突发病因的研究中已崭露头角 ,并在不断发展和完善之中。单纯病例研究的基本特征是研究对象仅用病例而不用对照。按其应用范围可分为四类 :病例分布研究 (case distributionstud…     

Effect of autocontrol micromotion intramedullary interlocking nail on fracture healing： an experimental study

Objective: To investigate the effect of autocontrol micromotion locking nail ( AMLN ) on experimental fracture healing and its mechanism. Methods: 16 goats undergoing both sides of transverse osteotomy of the femoral shafts were fixed intramedullary with AMLN and Gross-Kempf (GK) nail, respectively. The follow-up time was 7, 14, 28 and 56 days. Roentgenographic, biomechanical, histological, scanning electromicroscopic and biochemical analyses were done. Results: (1) The strength of anticompression, antiflexion and antitorsion in the fractural end in the AMLN-fixed group was higher than that of GK nail-fixed group; whereas, the rate of stress shelter in the fractured end decreased significantly (P<0.01). (2) The content of the total collagen, insoluble collagen, calcium and phosphate in the AMLN-fixed group was higher than that in the GK nail-fixed group (P<0.05). (3) Histological observation and quantitative analysis of calluses revealed that AMLN could promote the growth of bridge calluses and periosteum calluses. Hence the facture healing and remolding process achieved early, which was much better than traditional GK nail fixation. (P<0.05). (4) 7-14 days postoperation, the calluses of AMLN-fixed group was flourish and camellarly arranged and the collagen fibril formed constantly in the absorption lacuna of bone trabecula. 28-56 days postoperation, the collagen fibril was flourish around the absorption lacuna and was parallel to the bone's longitudinal axis. Active bony absorption and formation were seen, so was remolding and rebuilding. Haversian system was intact and the bony structural net was very tenacious because of the deposition of calcium salt. None of the above findings was observed in the GK nailfixed group. Conclusions: The design of AMLN accords well with the plastic fixation theory. As the geometry ametabolic system constituted by the intramedullary fixation instruments and the proximal and distal end of the fracture is very firm and stable, the disturbance to the physical stress distributed in the fractural end is light. The generation and conduct of the intermittent physical stress between the fractural parts could reach the balance between stress conduct and stress protection. The feature that the healing and remolding take place at the same time speeds up the fractural healing process.     

小儿哮喘危险因素临床分析

目的 探讨诱发哮喘的危险因素.方法 以问卷调查法总结2004～2006年河南科技大学第二附属医院儿科哮喘门诊及病房确诊的88例哮喘患儿的易感因素.结果 88例中有反复呼吸道感染84例(95.5%)、特异质81例(92%)、吸入过敏原57例(64.8%)、食入过敏原61例(69.3%)、人工喂养69例(78.4%)、早产儿和低体重儿63例(71.6%)、肥胖儿54例(61.4%)、天气变化(指气温骤降)52例(59.3%)、运动诱发39例(44.3%),其中吸入因素中被动吸烟38例(43.2%).两种以上因素76例(76.1%).结论 反复呼吸道感染是诱发哮喘的主要因素,多因素暴露对哮喘的发生起着关键性作用.     

甲基胂酸锌生产中的劳动卫生问题及其对细胞遗传效应的探讨

甲基肿酸锌是有机胂杀菌剂,对水稻纹枯病有较好疗效。为全面了解它在生产中的职业危害及对人类细胞遗传效应,1984年我们调查了某农药厂甲基胂酸锌生产车间的劳动卫生问题及对工人健康影响,现报告如下。方法和结果 (一)生产工艺与劳动条件。某农药厂甲基肿酸锌车间于1972年投产,产品为26％可湿性粉剂,其生产工艺流程: