IS THE SEVERITY OF OSTEOSCLEROSIS OF FLUOROSIS PROPORTIONAL TO THE DOSE OF FLUORIDE INTAKE?

Histomorphometric study was made on a series of sections of undecalcified epiphyseal femoral specimens from rats with experimental fluorosis. The results revealed osteosclerosis in Group A (5 ppm) being more severe than that in Group B (25 ppm) With the increase of fluoride dose, the parameters fell down instead of increased in parallel. There is seemingly a threshold over which osteosclerosis in fluorosis becomes less severe. In contrast to Bely's conclusion the authors proposed that, fluoride toxi- city, besides decreasing the number of osteoblasts, may also activate the osteoblasts. The number of osteoblasts may be increased with relative lower dose of fluoride also. The net outcome is the in crement in bone volume. When toxic dose of fluoride is higher enough (higher than the proposed threshold), however, the number of osteoblasts and its activity are inhibited. So are the osteocytes. This interpretation may be the cytological basis for osteosclerosis in the experimental fluorosis.     

冬凌草糖浆治疗慢性咽炎20例

目的 据世界卫生组织调查统计，慢性咽炎患病率高达80％以上，成年人为最多。严重危害着人们的身体健康。患者对慢性咽炎的困扰深恶痛绝，但知之甚少，使病情被忽视或逐年加重。为此广大医药工作者和患者均应引起高度重视。探索有效的治疗方法。方法用冬凌草糖浆治疗慢性咽，炎20例观察。结果 通过三个月治疗，治愈率达85％，有效率95％。结论 冬凌草糖浆治疗慢性咽炎效果显著。     

甜梦口服液配伍安定治疗顽固性失眠临床应用研究

失眠症是由多种因素引起的临床常见病症,患者难以入睡或睡后易醒,严重影响工作学习和日常生活.尤其是顽固性失眠,给予传统镇静催眠药(如安定)后效果不理想,由于病程较长,常引发精神异常和其他功能障碍,使患者身心遭受严重伤害,带来巨大痛苦.笔者在临床中用甜梦口服液配伍安定治疗顽固性失眠效果显著,故在动物实验的基础上制定了临床观察计划,对其配伍应用效果进行对比研究,现报告如下.     

糖尿病人高血压降压药物的选择

高血压是糖尿病人一个常见的并发症,它可促使其他并发症的发生,增加死亡率,因此要提高糖尿病的治疗效果,降低死亡率就必须及时有效的控制好血压。众所周知抗高血压药物可产生一些代谢方面的副作用,这对有代谢障碍的糖尿病人来说其副作用可能会更大,因此正确选择好糖尿病人的降血压药物是一个很重要的问题。     

Ⅳ型胶原和透明质酸测定早期肝纤维化的临床价值

肝纤维化是一切恶性肝病的共同病理学基础,是肝硬变的初级阶段,并与肝癌的发生有一定关系,肝纤维化是细胞外基质,合成和降解失衡的结果,在进入肝硬变之前尚有逆转的可能。Ⅳ型胶原和透明质酸是细胞外基质的主要成分,作为检测肝纤维化的指标[1]。我科通过检测56例健康人和108例肝病患者血清HA和IV-C的含量,并探讨其临床价值。     

内镜治疗胆漏18例临床分析

目的：探讨胆道术后胆漏内镜治疗的效果。方法：回顾性分析行内镜治疗18例胆道术后胆漏患者的临床资料。结果：18例胆漏全部治愈，随访6～12个月，无再发胆漏。结论：内镜下治疗胆漏具有安全、疗效肯定、创伤小和并发症少等优点。可作为大多数胆漏患者的首选治疗方法。