Fracture of the penis and long-term results of surgical treatment

Twenty-five patients with fracture of the penis were treated surgically between 1968 and 1984. Long-term follow-up was obtained in 17. In no case were there any early post-operative complications. All patients stated that they were achieving normal, painless erections; two patients developed a slight penile curvature but this did not affect their sexual activities. We strongly recommend early surgical intervention because of these encouraging results. Urethral injury associated with the fracture did not occur in this series.     

An unusual case of penile augmentation: subcutaneous stone implantation

Different techniques for penile augmentation have been published. We report a 45-year-old man who had undergone a subcutaneous penile stone implantation for enlargement, which is the first published report to our knowledge.     

Is midazolam effective as an antioxidant in preventing reperfusion injury in rat kidney?

This experimental study was designed to investigate whether midazolam hasantioxidant effects in reperfused rat kidneys following ischemia. TwentyWistar Albino rats were included in the study. Rats were anesthetized withthe mixture of ketamine 90 mg/kg and xylazine 10 mg/kg administeredintraperitoneally. Following anesthesia, the rats were divided into twogroups. The first group was considered as the control group, whereas thesecond group received additional midazolam 3.5 mg/kg intraperitoneally.The left kidney was approached via a transabdominal incision and the leftrenal artery was dissected. Left renal ischemia was created by clamping theleft renal artery for 45 minutes. Following the ischemia period, the kidneywas reperfused for one hour. Both kidneys were then removed. Half of theleft kidneys were immediately immersed in liquid nitrogen fortransportation and then frozen at –70 C until measurements of tissuemalondialdehyde (MDA) and glutathione (GSH) levels. The remaining halvesof the left kidneys and right kidneys were fixed in 10% formalin. Thechanges which developed during the ischemia-reperfusion period in theleft kidney were investigated by histopathological examination andcompared with those of the normal contralateral kidney.When compared with the control group, tissue MDA and GSH levels weresimilar in the midazolam group (p > 0.05). Tubular damage with tubulitis andfocal interstitial inflammatory infiltration were observed inhistopathological examinations of reperfused left kidneys of the controlgroup. There was PMNL infiltration only in perirenal fat tissue of themidazolam group. Right kidneys were histopathologically normal in bothgroups.We concluded that within this dosage midazolam does not have anyantioxidant effect in reperfused rat kidneys following ischemia.     

Spinal cord compression by primary amyloidoma of the spine

In this report, we presented a case of solitary spine amyloidoma, its clinical and radiological findings and management, and a review of the literature on vertebral amyloidosis.     

Thymidine labeling index in laryngeal squamous cell carcinoma in correlation with pTNM,age, histological grade and recurrence

In this study, our aim was to investigate the prognostic features of the thymidine labeling index (TLI) in laryngeal squamous cell carcinoma (SCC). The TLI values in tumor tissues and adjacent healthy tissues were assessed in 40 patients who had a pathological diagnosis of laryngeal SCC. The data were correlated with age, pTNM, histological grade and recurrence. The tissues (tumor and adjacent tumor-free tissue) obtained during surgery were labeled with (3)H-thymidine. A statistically significant difference was observed between tumoral tissue and adjacent tumor-free tissue (p < 0.05), but we could not confirm any statistically significant correlation between TLI and age, pTNM, histological grade and recurrence. In conclusion, TLI in laryngeal SCC had no significant relation with the clinicopathological features, probably due to the variation in tissue sampling and for tumor-dependent reasons. TLI may assist in differentiating malignant from benign lesions.     

Cochlear implantation in children with inner ear malformations: report of two cases

Cochlear implantation of congenitally deaf children with inner ear malformations is gaining special interest. Although the number of the reported cases is increasing, the decision for implantation needs thorough investigation. Preoperative evaluation, surgical approach and postoperative follow-up can be challenging. STUDY DESIGN: A retrospective analysis of two cases with inner ear malformations. PATIENTS: One patient was a 3-year-old-girl who had cochlear and cochleovestibular nerve aplasia on the left side and incomplete partition on the other side. The other patient was a 5-year-old-boy who had hypoplastic cochlea on both sides. Both of them also had vestibular anomalies. Cases were implanted by using multichannel cochlear implant. RESULTS: No complications were encountered. Both patients responded to acoustic stimuli, and their speech perception skills were improved. After 10 months of cochlear implant use, their results seem encouraging. CONCLUSION: Except cochlear or cochleovestibular nerve agenesis, inner ear malformations cannot be accepted as a contraindication for cochlear implantation. Although there can be difficulties during the surgery or in the postoperative period, patients with inner ear malformations can also benefit from cochlear implantation. It is essential that all possible complications and postoperative performance should be discussed with the parents.     

Ocular ochronosis: A case report and clinical findings

PURPOSE: To report a rare case of bilateral asymmetrical melanin-like pigments found in the cornea, conjunctiva and sclera. METHODS: Systemic investigation with clinical and laboratory analysis. RESULTS: The case was diagnosed as one of alkaptonuria and ocular ochronosis.