全文获取类型
收费全文 | 27312篇 |
免费 | 2027篇 |
国内免费 | 273篇 |
专业分类
耳鼻咽喉 | 530篇 |
儿科学 | 353篇 |
妇产科学 | 373篇 |
基础医学 | 4486篇 |
口腔科学 | 826篇 |
临床医学 | 2480篇 |
内科学 | 5263篇 |
皮肤病学 | 1026篇 |
神经病学 | 2054篇 |
特种医学 | 1608篇 |
外科学 | 3454篇 |
综合类 | 136篇 |
现状与发展 | 3篇 |
一般理论 | 8篇 |
预防医学 | 1051篇 |
眼科学 | 490篇 |
药学 | 2627篇 |
中国医学 | 425篇 |
肿瘤学 | 2419篇 |
出版年
2023年 | 152篇 |
2022年 | 115篇 |
2021年 | 1084篇 |
2020年 | 587篇 |
2019年 | 805篇 |
2018年 | 944篇 |
2017年 | 750篇 |
2016年 | 1103篇 |
2015年 | 1500篇 |
2014年 | 1573篇 |
2013年 | 1878篇 |
2012年 | 2693篇 |
2011年 | 2493篇 |
2010年 | 1515篇 |
2009年 | 1189篇 |
2008年 | 1651篇 |
2007年 | 1454篇 |
2006年 | 1248篇 |
2005年 | 1175篇 |
2004年 | 936篇 |
2003年 | 826篇 |
2002年 | 677篇 |
2001年 | 406篇 |
2000年 | 390篇 |
1999年 | 311篇 |
1998年 | 143篇 |
1997年 | 125篇 |
1996年 | 85篇 |
1995年 | 68篇 |
1994年 | 71篇 |
1993年 | 64篇 |
1992年 | 112篇 |
1991年 | 130篇 |
1990年 | 109篇 |
1989年 | 97篇 |
1988年 | 90篇 |
1987年 | 76篇 |
1986年 | 78篇 |
1985年 | 62篇 |
1984年 | 42篇 |
1983年 | 38篇 |
1979年 | 53篇 |
1978年 | 37篇 |
1975年 | 52篇 |
1974年 | 29篇 |
1972年 | 39篇 |
1971年 | 49篇 |
1970年 | 34篇 |
1969年 | 27篇 |
1968年 | 31篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
961.
962.
JW Shin SW Jung BR Park CJ Kim JB Eum BG Kim ID Jeong SJ Bang SH Lee SR Kim NH Park 《Journal of viral hepatitis》2012,19(10):724-731
Summary. Quantitative hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) assays are emerging as effective tools of on‐treatment predictors of response to antiviral agents, in addition to monitoring serum HBV DNA levels. However, the dynamic relationship between quantitative HBsAg, as well as HBeAg and HBV DNA, and the predictability of subsequent clinical outcomes during entecavir (ETV) therapy remain unclear. Eighty‐two patients with HBeAg‐positive chronic hepatitis B (CHB) received ETV therapy for ≥3 years. Virologic response (VR) after 3 years of ETV therapy was achieved in 73 (89.0%) patients. Among baseline and on‐treatment factors, on‐treatment HBV DNA levels performed better with respect to the prediction of response than HBsAg and HBeAg levels. Especially, the performance of absolute values of HBV DNA with respect to response was superior to HBV DNA decline from the baseline. The best predictive value was an absolute HBV DNA level of 2.3 log10 IU/mL at month 6 (areas under the curve [AUROC], 0.977; 95% CI, 0.940–1.000; P < 0.001). HBeAg seroconversion after 3 years of therapy was achieved in 26 (31.7%) patients. On‐treatment HBeAg levels performed better with respect to the prediction of seroconversion than HBsAg and HBV DNA levels. The best cut‐off value for the HBeAg level at month 12 for the prediction of seroconversion was 0.62 log10 PEIU/mL. Although the HBsAg level at baseline is often used to predict the antiviral potency of entecavir, on‐treatment HBV DNA and HBeAg levels are more helpful for prediction of subsequent clinical outcomes in HBeAg‐positive CHB patients with entecavir treatment. 相似文献
963.
964.
965.
Chung SW Kim YH Lee EJ Kim DH Kim GY 《The Brazilian journal of infectious diseases》2012,16(2):200-203
Sparganosis in humans is an incidental infection and is known to be associated with eating insufficiently cooked meat of frogs and snakes or drinking unboiled stream water. Although it can involve various internal organs, pulmonary and pleural involvement due to sparganum is rare. Because we recently experienced two cases involving lung parenchyma and pleura that were misdiagnosed as bacterial pneumonia and lung cancer, we herein intend to present them in detail. 相似文献
966.
967.
ABSTRACT: BACKGROUND: Despite screening blood donations with advanced technologies and improved donor screening, the risk of transfusion-transmitted infections persists. This risk is mainly due to blood donations collected during the window period. A precise estimate of the transfusion risk of viral infection will help to determine the effect of new and current safety measures and to prioritize and allocate limited resources. Therefore, we estimated the risk of transfusiontransmitted viral infection in blood donations collected in Korea from 2000 to 2010. METHODS: Blood donations collected at 16 blood centers were tested for HIV, HCV, and HBV to estimate the residual risk of transfusion-transmitted viral infection. The residual risk was calculated in two-year periods using the incidence/window model. The incidence rates for HIV/HCV and the confirmed positive rate for HIV/HCV in first-time and repeat donors were compared. RESULTS: The residual risks for HIV in 2004/2005 and 2009/2010 were 1 in 1,080,244 and 1 in 1,356,547, respectively. The risks for HCV in 2000/2001 and 2009/2010 were 1 in 81,431 and 1 in 2,984,415, and the risks for HBV in 2000/2001 and 2009/2010 were 1 in 45,891 and 1 in 43,666. These estimates indicate that the residual risks for HCV in Korea have declined 36.6-fold, and those for HIV and HBV have not improved significantly, compared to previous estimates. The odds ratios for HCV and HBV positivity in first-time donors compared to repeat donors were 11.8 and 19.6, respectively. CONCLUSIONS: The residual risk of HCV declined over the last decade due to improved screening reagents, implementation of the nucleic acid amplification test, and tight application of strict donor selection procedures. Current residual risk estimates for HIV and HCV in Korea are extremely low, but the risk for HBV is still high; therefore, urgent measures should focus on decreasing the residual risk of HBV. Despite the introduction of more sensitive assays in blood screening, several other factors may influence the actual residual risk of transfusiontransmitted infection. A continuous monitoring of residual risk of transfusion-transmitted infection is crucial in managing blood safety. 相似文献
968.
969.
Bo Ram Kim So Hyun Kim JaeSang Ko Seung Woon Baek Yung Kyung Park Yoon Jung Kim Jin Sook Yoon 《Korean journal of ophthalmology : KJO》2021,35(1):37
PurposeWe sought to evaluate the safety and effectiveness of patient-specific ocular prostheses produced by three-dimensional (3D) printing and the sublimation technique. A comparison with prostheses produced using manual manufacturing methods was then performed.MethodsTo confirm the biological and physiochemical safety, cytotoxicity, systemic acute toxicity, intradermal reaction, and skin sensitization tests were conducted according to the International Organization for Standardization guidelines. The compressive strength of the prostheses was also tested. Further, a case series of three patients who wore the 3D printed prostheses for more than eight hours daily for 4 weeks was executed. Self-assessments by these individuals using a questionnaire and safety evaluations focusing on the occurrence of conjunctival inflammation or allergic reactions according to the Cornea and Contact Lens Research Unit criteria by slit-lamp examination and similarity assessment were completed.ResultsThe 3D printed ocular prostheses met the necessary qualifications per the biological and physiochemical safety tests, showing the absence of cytotoxicity, acute systemic toxicity, intradermal reactivity, and skin-sensitizing potency. Also, there was no difference in strength test results between previous ocular prostheses and the 3D printed ones. Self-assessment by the patients yielded satisfactory results, with no significant difference in the level of satisfaction reported for the 3D printed and previous handmade ocular prostheses. The 3D printed prosthesis did not trigger any side effects in the conjunctival sac and showed similar objective findings with respect to the color of the iris, sclera, and vessel patterns.ConclusionsOur study confirms the biologic and physiochemical safety of 3D-printed ocular prostheses created using computer-aided design technology and a sublimation technique. The patients’ questionnaires and the judgment of the ophthalmologists/ocularists showed that the 3D printed ocular prosthesis was acceptable in function and appearance through a case series report. 相似文献
970.
Kim Bo Ram Seo Yuri Lee Hyun Jung Chung So-Hyang Yoon Jin Sook 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2021,259(7):2055-2055
Graefe's Archive for Clinical and Experimental Ophthalmology - In the original publication, affiliations 1 and 4 are the same. Yuri Seo's affiliaiton should also be changed to Yongin... 相似文献