全文获取类型
收费全文 | 105994篇 |
免费 | 6841篇 |
国内免费 | 876篇 |
专业分类
耳鼻咽喉 | 1231篇 |
儿科学 | 3144篇 |
妇产科学 | 2598篇 |
基础医学 | 13992篇 |
口腔科学 | 2582篇 |
临床医学 | 8538篇 |
内科学 | 23604篇 |
皮肤病学 | 2214篇 |
神经病学 | 9992篇 |
特种医学 | 4338篇 |
外国民族医学 | 23篇 |
外科学 | 15585篇 |
综合类 | 1674篇 |
一般理论 | 52篇 |
预防医学 | 5679篇 |
眼科学 | 1661篇 |
药学 | 8292篇 |
3篇 | |
中国医学 | 521篇 |
肿瘤学 | 7988篇 |
出版年
2023年 | 508篇 |
2022年 | 555篇 |
2021年 | 2299篇 |
2020年 | 1443篇 |
2019年 | 2028篇 |
2018年 | 2488篇 |
2017年 | 1924篇 |
2016年 | 2017篇 |
2015年 | 2347篇 |
2014年 | 3013篇 |
2013年 | 4310篇 |
2012年 | 5858篇 |
2011年 | 6015篇 |
2010年 | 3834篇 |
2009年 | 3389篇 |
2008年 | 5259篇 |
2007年 | 5360篇 |
2006年 | 5036篇 |
2005年 | 4827篇 |
2004年 | 5048篇 |
2003年 | 4850篇 |
2002年 | 4896篇 |
2001年 | 3813篇 |
2000年 | 3767篇 |
1999年 | 3062篇 |
1998年 | 1202篇 |
1997年 | 947篇 |
1996年 | 879篇 |
1995年 | 846篇 |
1994年 | 725篇 |
1993年 | 698篇 |
1992年 | 1834篇 |
1991年 | 1797篇 |
1990年 | 1526篇 |
1989年 | 1471篇 |
1988年 | 1353篇 |
1987年 | 1202篇 |
1986年 | 1182篇 |
1985年 | 1050篇 |
1984年 | 769篇 |
1983年 | 705篇 |
1982年 | 453篇 |
1981年 | 383篇 |
1979年 | 582篇 |
1978年 | 427篇 |
1975年 | 434篇 |
1974年 | 487篇 |
1973年 | 463篇 |
1972年 | 428篇 |
1971年 | 394篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
31.
Femoral access‐related complications during percutaneous transcatheter aortic valve implantation comparing single versus double Prostar XL device closure 下载免费PDF全文
32.
33.
Raffaella Marcheselli Alessia Bari Tamar Tadmor Luigi Marcheselli Maria Christina Cox Robel Papotti Angela Ferrari Luca Baldini Paolo Gobbi Ilana Levy Giuseppe Pugliese Massimo Federico Aaron Polliack Samantha Pozzi Stefano Sacchi 《Hematological oncology》2020,38(4):439-445
The main purpose of this study was to assess whether it is possible to improve the prognostic impact of international prognostic index (IPI) score by combining it with peripheral blood counts. Thus, we evaluated the prognostic power of lymphocyte, neutrophil, and monocyte counts in 520 patients with diffuse large B cell lymphoma treated with R-CHOP, confirming that these parameters have a strong impact on overall survival (OS). Using revised IPI (R-IPI), 44% of patients were categorized as poor-risk and showed an OS at 5 years of 46%. As OS at 5 years of the 520 patients is 67%, it is clearly evident that R-IPI tends to overestimate the proportion of patients with poor prognosis. Accordingly, in an attempt to improve the discriminating power of R-IPI, we evaluated and compared three different scores by combining the neutrophil lymphocyte ratio (NLR) and absolute monocyte count (AMC) with the following values: (a) IPI score 3-5, (b) age > 60 years and performance status, (c) age ≥ 65 years and LDH > ULN. The three indexes studied, had a similar 5 years OS for the high-risk group (46%-52%), but the proportion of patients classified as poor-risk were 37%, 20%, and 32%, respectively, which are lower than 44% identified with R-IPI. Thus, while R-IPI overestimates the number of high-risk patients, after applying our models, it is possible to recognize patients who are truly at high-risk. Of the three scores, the most accurate appears to be that based on NLR, AMC, LDH > ULN and age ≥ 65 years, which identifies 32% of high-risk patients, correlating well with what is seen in clinical practice. 相似文献
34.
35.
Psychological characteristics and physiological reactivity to acute stress in mothers of children with autism spectrum disorder 总被引:1,自引:0,他引:1
Elena Pattini Luca Carnevali Alfonso Troisi Guido Matrella Dolores Rollo Mauro Fornari Andrea Sgoifo 《Stress and health》2019,35(4):421-431
Stress related to parenting a child with autism spectrum disorder can differently affect caregiver's physiological reactivity to acute stress. Here, parental stress levels, psychological characteristics, and coping strategies were assessed alongside measures of heart rate, heart rate variability, and cortisol during a psychosocial stress test in mothers of children with ASD (M‐ASD, n = 15) and mothers of typically developing children (n = 15). M‐ASD reported significantly higher levels of parental stress, anxiety, negative affectivity, social inhibition, and a larger preference for avoidance strategies. M‐ASD showed larger heart rate and cortisol responses to the psychosocial stress test. A positive relationship was found between parental stress levels and the magnitude of the cortisol stress response in both groups. The present findings indicate exaggerated physiological reactivity to acute psychosocial stress in M‐ASD and prompt further research to explore the role of individual differences in mediating the effects of parental stress on physiological stress responses. 相似文献
36.
Miguel A. Sanz Pau Montesinos Haesook T. Kim Guillermo J. Ruiz-Argüelles María S. Undurraga María R. Uriarte Lem Martínez Rafael H. Jacomo Homero Gutiérrez-Aguirre Raul A. M. Melo Rosane Bittencourt Ricardo Pasquini Katia Pagnano Evandro M. Fagundes Edo Vellenga Alexandra Holowiecka Ana J. González-Huerta Pascual Fernández Javier De la Serna Salut Brunet Elena De Lisa José González-Campos José M. Ribera Isabel Krsnik Arnold Ganser Nancy Berliner Raul C. Ribeiro Francesco Lo-Coco Bob L?wenberg Eduardo M. Rego 《Annals of hematology》2015,94(8):1347-1356
37.
Alessandro De Cassai Tommaso Tonetti Helmut Galligioni Carlo Ori 《Brazilian Journal of Anesthesiology》2019,69(1):95-98
Background and objective
Erector spinae plane block is a valid technique to provide simultaneously analgesia for combined thoracic and abdominal surgery.Case report
A patient underwent open esophagectomy followed by reconstructive esophagogastroplasty but refused thoracic epidural analgesia; a multi‐modal analgesia with a multiple erector spinae plane block was then planned. Three erector spinae plane catheters (T5 and T10 on the right side and T9 on the left side) for continuous analgesia were placed before surgery. During the first 48 h pain was never reported in the thoracic area but the patient reported multiple times to feel a pain well localized in epigastrium, but never localized in any other abdominal quadrant.Discussion
Erector spinae plane block is a valid technique to provide analgesia simultaneously for combined thoracic and abdominal surgery and could be a valid alternative strategy if the use of epidural analgesia is contraindicated. 相似文献38.
Aoife De Brún Liran Shan Áine Regan Áine McConnon Patrick Wall 《Health communication》2016,31(10):1235-1241
The 2008 dioxin crisis occurred as a result of contamination of Irish pork. The event had significant implications for Ireland’s economy and the reputation of its agricultural industry, as well as raising concerns for human health. This study describes the results of a content analysis of Irish and UK newspaper coverage of the 2008 Irish dioxin crisis, as this is likely to provide insight into how public perceptions of this issue were shaped. Articles from 16 print publications were systematically sampled for the period December 2008 to February 2009. The resulting data set of 141 articles was examined using a coding protocol developed based on previous research and refined during piloting. Results indicated that the dioxin crisis was primarily portrayed by the media as an industry/economic crisis, dominant in 26.9% of articles in the sample. Within this dominant portrayal, the agricultural industry was frequently cited as being in crisis (42.6%); however, the implications of the crisis on the wider economic environment also received attention (17.7%). Differences between Irish and UK-based media were also examined, revealing that while the Irish media most frequently described the crisis in terms of its impact on the industry and economy, the UK media were more likely to portray the crisis as a risk to health. These dominant media messages and message framings have implications for the public understanding of the issue in each country and potential consequences regarding perception of the adequacy of existing food policy and regulatory oversight. 相似文献
39.
Alessandro Abbouda Paolo Tortorella Lucia Restivo Elisa Santoro Federica De Marco Maurizio La Cava 《Seminars in ophthalmology》2016,31(6):532-541
Purpose: To evaluate the rate and onset of intraoperative and postoperative complications post-phacoemulsification. Methods: One hundred sixty-two eyes of 145 patients with uveitis who underwent phacoemulsification between 2006 and 2009 were identified through surgical record review. Fifty-nine eyes of 46 patients met the inclusion criteria. Hazard ratio (HR) and Kaplan-Meier survival probability were calculated for each class of uveitis. Results: Macular edema (ME) resulted to be associated to chronic postoperative inflammation (r?=?0.6; p?=?0.00) and mostly related to patients who presented more than one postoperative relapse/year (r?=?0.2; p?=?0.02). Fuchs uveitis resulted to be a risk factor for posterior capsule opacification (PCO) (HR 3.36 IC95%1.0-10.5; p?=?0.03). Hypotony and elevated intraocular pressure (IOP) were detected in the anterior uveitis group (0.02 EY). Conclusion: The HR to develop ME was significantly related to chronic anterior uveitis. PCO and elevated IOP are most frequent in Fuchs uveitis. The postoperative visual acuity result was good among all the uveitis groups. 相似文献
40.
Albert De Decker Rosalie Fergusson Benjamin Ondruschka Niels Hammer Johann Zwirner 《Clinical anatomy (New York, N.Y.)》2020,33(4):522-529
For 50 years now, sacrospinous ligament fixation (SSLF) has been used to treat pelvic organ prolapse consequent on altered integrity of the pelvic myofascial structures. It is usually performed vaginally, but it has recently been performed laparoscopically through either an anterior or a posterior approach, with the broad ligament as a landmark to differentiate the two. In the present study, these two laparoscopic approaches were assessed using Thiel-embalmed cadavers. The anterior and posterior approaches were compared in terms of the closest distance to anatomical structures at risk, including pelvic viscera, the obturator nerve, and vascular structures. The posterior approach was more often closer to the investigated vessels and the rectum. The obturator nerve and the ureter were close to both the anterior and posterior approaches. The urinary bladder was closer using the anterior approach. From an anatomical standpoint, therefore, the anterior laparoscopic approach for SSLF is more likely to cause injury to the urinary bladder, whereas the posterior approach is more prone to causing rectal and vessel injuries. This study illustrates, from a basic science perspective, the importance of combining fascia research, novel endoscopic or minimally invasive surgical exposures informed by anatomy, and contemporary trends in gynecology in order to improve patient outcomes. Clin. Anat. 33:522–529, 2020. © 2019 Wiley Periodicals, Inc. 相似文献