Perceived social support in the lives of gay,bisexual and queer Hispanic college men

In this qualitative study, we examined the sources and nature of social support reported by 24 gay, bisexual and queer Hispanic college men at a small liberal arts college and a large university in the USA. We identified four themes of support across the interviews: Shared experiences (46%), Protector (42%), Support in the air (33%) and Gradual support (29%). Shared experiences included support from those who had previous experience with the lesbian, gay or bisexual community. Protector indicated a type of support that was psychologically, emotionally or physically protective in nature. Participants also reported receiving indirect support such as nonverbal behaviours or indirect gestures of endorsement and caring (support in the air). Participants reported that many of their network members came to support them gradually over time (gradual support). Within each theme we found support from both women and men, who provided support in gender-consistent ways. Our results highlight that despite continued prejudice and discrimination in society, sexual and racial/ethnic minority men have strongholds of support from men and women in their lives that enable them to navigate their development successfully.     

Impact of forest fires on PAH level and distribution in soils

Surface (0–5 cm) and subsurface (−5 to 15 cm) soils from burned forest areas in South of France were analyzed to determine contents of 14 priority polycyclic aromatic hydrocarbons (PAHs) and their distribution profile. The sampling procedure allowed us to study the effect of the frequency of fire as well as the influence of the time elapsed since the last fire. The contribution of forest fires to the content of PAHs in soils was demonstrated, as well as the decrease of their total level with time. The hypothesis is that a natural remediation takes place a few years after the last fire event. The lowest molecular weight studied PAHs (naphthalene, acenaphtene, fluorene, phenanthrene, anthracene, fluoranthene and pyrene) appear to be the major ones produced by forest fire. Naphtalene levels are remarkably high in burned soils (more than 70 μg kg⁻¹, i.e. more than 20 times higher than in the control soils) and still remain important years after the last fire event. The time elapsed since the last fire appears to be a more influencing factor than the fire frequency. The index defined from the PAH levels shows values reflecting the time elapsed since the last fire.     

人口老龄化与老年残疾人状况分析

老龄化是当代人口发展的必然趋势.在人口老龄化的过程中,老年残疾人的数量也大幅增长.老年残疾人作为特殊群体,应受到社会的特别关注.在分析人口老龄化与老年残疾人增长之间关系的基础上,进一步对我国老年残疾人的状况、老年残疾人的等级及致残原因进行了分析,并提出了人口老龄化状况下的残疾预防对策.     

Physical and chemical characterization of mefenamic acid in different pharmaceutical dosage forms and their stability studies using novel RP-HPLC method

A novel RP-HPLC method for the determination of mefenamic acid in raw material, different pharmaceutical forms, and in human serum for routine analysis, therapeutic purposes, and stability studies was developed and validated. This study is also a collection of studies performed on the physical and chemical aspects of mefenamic acid. The method developed constitutes mobile phase, acetonitrile:acetic acid:water (72.5:1:26.5, v/v/v) at pH 3 and mefenamic acid was monitored with UV detection at 279?nm, eluting out at 3.98?min. The present HPLC method was found to be linear (100–300?μg?mL^?1), accurate, and least time consuming with very good recovery. The limits of detection of the method were found to be 10?μg?mL^?1. This method was also used to study the stability profile of mefenamic acid in tablets for 5?years and suspension for 4?years. The excipients present in the formulation did not interfere with the assay. The present method was also compared with the UV–visible technique and it was observed that HPLC method is more precise, sensitive, and accurate.     

The association with age,human tissue kallikreins 6 and 10 and hemostatic markers for survival outcome from epithelial ovarian cancer

Purpose  

To assess known cancer biomarkers CA-125, human tissue kallikreins KLK6 and KLK10, hemostatic markers and age with 5-year survival outcome from epithelial ovarian cancer.     

Colorectal neoplasm in asymptomatic Asians: a prospective multinational multicenter colonoscopy survey

BACKGROUND: Colorectal neoplasm is rapidly increasing in Asia, but a guideline for screening is not available. OBJECTIVE: To evaluate the characteristics of colorectal neoplasm in asymptomatic Asian subjects. DESIGN: Prospective cohort study. SETTING: Multinational multicenters, including both primary and referral centers in Asia. PATIENTS: A total of 860 consecutive asymptomatic adults undergoing screening colonoscopy in 11 Asian cities from July 2004 to December 2004. Patients under 16 years old; those patients with a colorectal resection history, colonoscopies, or barium enema within 5 years; symptoms suggestive of colorectal diseases; and those who had undergone surveillance colonoscopy were excluded. MAIN OUTCOME MEASUREMENTS: The incidence and distribution of colorectal neoplasm and advanced neoplasm. RESULTS: The mean age (+/-SD) was 54.4+/-11.6 years; 471 were men (54.8%). The prevalence of colorectal neoplasm and advanced neoplasm was 18.5% and 4.5%, respectively. Male sex, advancing age, and a family history of colorectal cancer were risk factors for advanced neoplasm. Of the 168 patients with colorectal neoplasm, 76 had distal neoplasm only (45.2%), 66 had proximal neoplasm only (39.3%), and 26 had both proximal and distal neoplasms (15.5%). Although the presence of distal advanced neoplasm was a significant risk factor for proximal advanced neoplasm, 14 of the 758 subjects without distal neoplasm had proximal advanced neoplasm (1.8%). LIMITATIONS: The small number of enrolled subjects, especially from certain ethnic groups. CONCLUSIONS: The overall prevalence of advanced colorectal neoplasm in asymptomatic Asians is comparable with the West. Male sex, advancing age, and a family history of colorectal cancer were associated with a higher risk of advanced neoplasm.     

Isolated CNS Whipple disease: acute onset and relapsing-remitting course

Isolated CNS Whipple disease (WD) carries a poor prognosis, particularly if untreated. We describe 2 patients with isolated CNS WD who presented unusually with an acute onset followed by a relapsing-remitting course. Neither was diagnosed with WD until they had had several relapses.