全文获取类型
收费全文 | 1383篇 |
免费 | 56篇 |
国内免费 | 7篇 |
专业分类
耳鼻咽喉 | 32篇 |
儿科学 | 37篇 |
妇产科学 | 38篇 |
基础医学 | 185篇 |
口腔科学 | 11篇 |
临床医学 | 68篇 |
内科学 | 301篇 |
皮肤病学 | 17篇 |
神经病学 | 79篇 |
特种医学 | 29篇 |
外科学 | 125篇 |
综合类 | 15篇 |
预防医学 | 196篇 |
眼科学 | 36篇 |
药学 | 97篇 |
中国医学 | 4篇 |
肿瘤学 | 176篇 |
出版年
2023年 | 3篇 |
2022年 | 14篇 |
2021年 | 72篇 |
2020年 | 38篇 |
2019年 | 28篇 |
2018年 | 38篇 |
2017年 | 29篇 |
2016年 | 31篇 |
2015年 | 36篇 |
2014年 | 45篇 |
2013年 | 62篇 |
2012年 | 108篇 |
2011年 | 112篇 |
2010年 | 57篇 |
2009年 | 54篇 |
2008年 | 86篇 |
2007年 | 122篇 |
2006年 | 120篇 |
2005年 | 86篇 |
2004年 | 94篇 |
2003年 | 62篇 |
2002年 | 80篇 |
2001年 | 8篇 |
2000年 | 2篇 |
1999年 | 5篇 |
1998年 | 9篇 |
1997年 | 3篇 |
1996年 | 9篇 |
1995年 | 2篇 |
1994年 | 4篇 |
1992年 | 3篇 |
1989年 | 3篇 |
1988年 | 3篇 |
1987年 | 1篇 |
1986年 | 1篇 |
1985年 | 3篇 |
1984年 | 1篇 |
1983年 | 2篇 |
1982年 | 1篇 |
1980年 | 4篇 |
1977年 | 2篇 |
1976年 | 1篇 |
1974年 | 1篇 |
1960年 | 1篇 |
排序方式: 共有1446条查询结果,搜索用时 15 毫秒
101.
van Kranen HJ Mortensen A Sørensen IK van den Berg-Wijnands J Beems R Nurmi T Adlercreutz H van Kreijl CF 《Nutrition and cancer》2003,45(2):203-210
Phytoestrogens, like isoflavonoids and lignans, have been postulated as possible colorectal cancer protective constituents. To investigate this hypothesis, two high-fiber sources rich in lignan precursors, i.e., rye bran and flaxseed, were tested for their ability to modulate intestinal tumor development in ApcMin mice. Test diets consisted of a control diet (a Western-style diet, adjusted for fiber and/or phytate content) supplemented with 5% flaxseed or 30% rye bran. Chemical analysis of diets and blood samples confirmed the enhanced systemic exposure of mice fed the test diets to the major lignan precursors, i.e., secoisolariciresinol and matairesinol. No statistically significant difference was observed in the incidence and multiplicity of small intestinal and colon tumors at terminal sacrifice between mice fed the control diet or the diet supplemented with 5% flaxseed. With the rye bran diet a statistically significant enhancement of the number of small intestinal tumors in female mice was observed. The number of colon tumors, however, was comparable between the control and rye bran-fed mice of either sex. Furthermore, no activating point mutations in the K-ras oncogene nor positive immunohistochemical staining for the p53 gene were observed in a set of 48 colon tumors. In conclusion, our results demonstrate that increased intake of lignan precursors from flaxseed or rye bran, administered in a Western-style diet, does not protect against intestinal tumor development in an appropriate animal model for intestinal neoplasia such as the ApcMin mice. 相似文献
102.
Bartnik W Bartnik-Krystalska A 《Otolaryngologia polska. The Polish otolaryngology》2003,57(4):527-530
Treatment and results of 13 laryngeal and trachea traumas have been presented. All patients were operated in 24 hours after the injury. We had good results, only two patients had vocal chord paralysis. After phoniatric rehabilitation they regained good voice. 相似文献
103.
104.
105.
Marcin Barczynski Aleksander Konturek Alicja Hubalewska-Dydejczyk Stanislaw Cichon Wojciech Nowak 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2009,394(5):843-849
Background and aims Intraoperative parathyroid hormone assay (IOPTH) has been used during minimally invasive parathyroidectomy (MIP) to predict
operative success. However, the applied criteria are not equivalent in detection of multiglandular disease (MGD) and predicting
cure. The purpose of this study was to evaluate the most commonly applied criteria of IOPTH in patients undergoing MIP in
a tertiary referral center.
Materials and methods A retrospective review of 260 patients with sporadic primary hyperparathyroidism and concordant results of sestamibi scanning
and ultrasound of the neck undergoing MIP (135 video-assisted and 125 open) between Dec 2002 and May 2008, with a 6-month
postoperative follow-up of intact parathyroid hormone and serum calcium levels, was performed. The main outcome measures included
evaluation of predictive values of Halle, Miami, Rome, and Vienna IOPTH interpretation criteria.
Results The following overall accuracy, sensitivity, specificity, positive predictive value, and negative predictive values were found,
respectively: 65%, 62.9%, 100%, 100%, and 14.2% for Halle criterion; 97.3%, 97.6%, 93.3%, 99.6%, and 70% for Miami criterion;
83.8%, 82,9%, 100%, 100%, and 26.3% for Rome criterion; and 92.3%, 92.2%, 93.3%, 99.6%, and 60.9% for Vienna criterion.
Conclusions Miami criterion followed by Vienna criterion was found to be the best balanced among other criteria, with the highest accuracy
in intraoperative prediction of cure. However, Rome criterion followed by Halle criterion was found to be the most useful
in intraoperative detection of MGD. Nevertheless, their application in patients qualified for MIP with concordant results
of sestamibi scanning and ultrasound of the neck would result in a significantly higher number of negative conversions to
bilateral neck explorations and only a marginal improvement in the success rate of primary operations.
Presented at the 3rd Workshop of the European Society of Endocrine Surgeons (ESES), “Modern techniques in primary hyperparathyroidism
surgery: An evidence based perspective”, 19-21 of March 2009, Lund, Sweden. 相似文献
106.
107.
Alicja Tymczewska Bliss Ursula Furtado Jacek Nowaczyk Katarzyna Hrynkiewicz Aleksandra Szydowska-Czerniak 《Materials》2021,14(11)
The use of industrial waste as a material for the development of natural innovative and active packaging is economically and environmentally appealing. The aim of this study was to develop and characterize active gelatin films incorporating rapeseed oil industry waste. Water (RM-WE) and methanolic (RM-MWE) extracts of rapeseed meal (RM) were used as active agents in film formulations. The active films were produced by a casting technique. The physicochemical, mechanical, optical, morphological, radical scavenging, and antibacterial properties of the films were analyzed. The addition of RM-WE and RM-MWE in the concentrations range between 4 and 12% promoted an increase of Young’s modulus (YM) and radical scavenging properties of films investigated by the direct QUick, Easy, New, CHEap and Reproducible procedure using 2,2-diphenyl-1-picrylhydrazyl (QUENCHERDPPH) and 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (QUENCHERABTS) radicals. The antibacterial properties of films were examined against five bacterial strains: E. coli, S. enterica, M. luteus, L. monocytogenes, and S. aureus. Additionally, color and opacity of the control and fortified films differed significantly. The gelatin films with RM extracts are resistant to the microbial spoilage and could be used to produce active packaging for food that is vulnerable to rancidity effects. 相似文献
108.
109.
110.
Comparative evaluation of simple indices using a single fasting blood sample to estimate beta cell function after islet transplantation
下载免费PDF全文
![点击此处可从《American journal of transplantation》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Justyna E. Gołębiewska Julia Solomina Celeste Thomas Mark R. Kijek Piotr J. Bachul Lindsay Basto Karolina Gołąb Ling‐jia Wang Natalie Fillman Martin Tibudan Kamil Ciepły Louis Philipson Alicja Dębska‐Ślizień J. Michael Millis John Fung Piotr Witkowski 《American journal of transplantation》2018,18(4):990-997