甘露醇脱水联合硬膜外封闭治疗腰椎间盘突出症128例

腰椎间盘突出症对于大多数初次发病的患者均应考虑非手术治疗。但传统的非手术疗法疗程长,见效慢。我科自2000年以来,采用甘露醇脱水联合皮质激素硬膜外封闭治疗腰椎间盘突出症128例,效果明显,现报告如下。 1临床资料 1.1 一般资料 本组128例,男108例,女20例;年龄18～56岁。病程10 d～1年不等,无明显诱因62例,明显外伤史8例,职业工种原因58例。单纯腰痛12例,单纯下肢疼痛10例,余均有腰痛伴程度不等的下肢放射痛症状,无大小便障碍和鞍区感觉异常等马尾神经受压病例。所有病例均摄X线片和行CT检查,脱垂游离型和腰椎管狭窄者不在此列。     

sCD40L蛋白联合彩超对卵巢成熟畸胎瘤的临床诊断价值研究

目的 分析sCD40L蛋白联合彩超对卵巢成熟畸胎瘤的临床诊断价值。方法 本文选取2021年3月～2022年7月之间濮阳市妇幼保健院诊治的成熟卵巢畸胎瘤患者89例设为观察组，另取于同期进行健康体检者50例设为对照组。所有患者均采用彩色多普勒超声诊断仪经腹部、阴道探查；双抗体夹心法测定sCD40L蛋白含量；比较两组彩超检查结果、sCD40L蛋白含量；分析彩超、sCD40L蛋白对卵巢成熟畸胎瘤的诊断价值。结果 与对照组相比，观察组研究对象sCD40L蛋白、子宫动脉阻力指数RI、搏动指数PI、螺旋动脉血流阻力指数RI、搏动指数PI较低，内膜厚度、内膜3D-PDA参数血管指数VI、血流指数FI、血管化血流指数VFI较高，有统计学差异(P<0.05)。彩超、sCD40L蛋白联合诊断AUC值(0.838)高于彩超(0.764)、sCD40L蛋白(0.774)。结论 对卵巢成熟畸胎瘤患者进行彩超检测研究所得出的彩超结果和sCD40L蛋白水平与患者病情密切相关，二者联合可有效提高卵巢成熟畸胎瘤的临床诊断准确性。     

Audio frequency and acupuncture point pressing to treat retention of urine

Background：Retentionofurineisacommandcomplicationforthepostoperativepatientswhoreceptethegeneralorvertebralcanalanesthesia．Becausethemicturitionreflexcenteristemporarilydis－turbedbytheanesthetic，thevegetativenervesystemthatcontrolthebladderisfunctionaldisorder．Theurinarybladdersphincterrela－tivelycontracts，andthedetrusorurinaeofbladderrelativelyrelax．Objective：Todiscusstheeffectofaudiofrequencyandacupuncturepointpressingtotreatretentionofurine．Unit：GeneralHospitalofShenyangMilita…     

脂肪肝影像学评价的研究进展

目的评价影像学技术在肝脂肪变性的定性及定量诊断中的价值。方法对比超声、CT及MRI对肝脂肪变性的定性及定量诊断的临床应用现况，总结它们各自的进展情况及其优、缺点。结果超声可对肝脂肪变性的定性及定量诊断进行初步的筛选和估计，CT对肝脂肪变性的定量诊断更为可靠，MRI则具有更高的灵敏度和特异性。结论影像学在肝脂肪变性的定性及定量诊断中具有重要的临床价值，特别是MRI波谱成像及双梯度回波成像可对肝脂肪变性作出准确的定量诊断。     

肾移植患者血清sIL-2R测定的意义

白细胞介素 2 (IL - 2 )是体内重要的细胞因子之一。其在免疫应答反应中的重要作用 ,是通过与靶细胞膜上的白细胞介素2受体 (IL - 2 R)的结合来实现的。 T细胞受有丝分裂原或抗原激活后会在细胞膜上表达 IL - 2 R,并释放可溶性 IL - 2 R(s IL - 2 R)到细胞外液中。近年来 ,一些研究提示 ,测定 s IL- 2 R在肾移植免疫监测中有一定价值[1 ,2 ] 。我们采用酶联免疫法 (ELISA法 )对肾移植患者血清 s IL- 2 R进行了检测 ,并对其临床意义进行了探讨。1　对象与方法1.1　对象　同种肾移植患者 39例。其中男 2 3例 ,女 16例 ;年龄 2 7～ …     

肾移植病人的饮食康复治疗

Background:Now renal transplantation is extensively used and recetpted in the clinic for treating chronic renal failure.Nutrition support and diet treatment are necessary for postoperative rehabilitation of patients underwent renal transplantation.Rigid nutrition treatment could prevent and treatment postoperative diabetes mellitus,hypertension and hyperlipemia.Diet control was also necessary for patients receiving immunodepressant.Standards and protocol for diet treatment are unavailable now.The incidence of acute rejection and allograft failure during the first year posttransplantation has been greatly reduced by advances in operative techniques, immunosuppressive agents and our understanding of their toxicities, donor selection and preservation, and donor and patient management. However, life-long immunosuppression is required to prevent the development of chronic rejection. Thus, either chronic rejection or the adverse side effects of chronic immunosuppression limit long-term survival. There is increasing incidence that posttransplant lipoprotein abnormalities may contribute to the development of cardiovascular disease (CVD). CVD is one of the most common causes of morbidity and mortality following renal transplantation. In addition, there is some indirect evidence that posttransplant lipoprotein abnormalities may influence the progression of chronic transplant nephropathy. While there are no intervention trials examining whether antilipemic therapy is beneficial in the prevention of CVD in renal transplant patients, it is reasonable to assume that the benefits of treating hyperlipidemia in renal transplant recipients may be comparable to those found in the general population. Objective:Protocol for diet treatment was determined for patients underwent renal transplantation to reduce renal load,promote recovery of renal function,and decreased the incidence of complications.     

老年男性高血压病患者健康教育效果评价

目的评价对老年男性高血压病患者实施健康教育的效果。方法采用随机整群抽取法对120例老年男性高血压病患者进行高血压病相关知识健康教育,并比较实施教育前后的差异。结果通过实施健康教育,多数患者改变了以往的不健康生活方式,80%以上的患者做到情绪稳定、生活规律、不吸烟、少饮酒,66%的患者饮食结构更为合理;患者的血压控制更为理想,尤其是收缩压明显降低(P<0.01)。结论对干部门诊老年男性高血压病患者实施健康教育效果明显。     

人喉癌细胞异质性亚群的克隆分离及性质初探

目的通过原代培养人喉癌细胞、克隆分离异质性细胞亚群,初步探讨喉癌异质性机制。方法原代培养人喉癌细胞,采用有限稀释法单细胞体外培养喉癌细胞,比较克隆分离得到的异质性亚群在功能状态、细胞周期、形态、在无血清干细胞培养基中生长情况及裸鼠异体移植成瘤能力等方面的差异。结果分离得到Ⅰ型和Ⅱ型两个具有明显形态差异的细胞亚群。Ⅰ型细胞呈多角形,突起多,裸鼠移植可成瘤(4/5);而Ⅱ型细胞呈长梭形,突起较少,裸鼠异体移植不成瘤(0/5)。Ⅰ型与Ⅱ型细胞相比,RNA含量低,体外增殖能力强,能在无血清干细胞培养基中聚集呈肿瘤细胞球状生长;Ⅰ型细胞处于细胞周期G0/G1的比例明显高于Ⅱ型细胞。对Ⅰ型细胞亚克隆培养,产生的子代克隆集落出现了异质性的细胞,而Ⅱ型细胞亚克隆培养未能产生子代细胞。结论原发性喉癌细胞中存在着异质性的肿瘤细胞亚群,Ⅰ型细胞具备肿瘤干细胞的特性。     

Analysis of TGFBI gene mutation in a Chinese family with atypical Reis-Bückler corneal dystrophy

Objective To identify the TGFBI gene mutation and the relationship between genotype and phenotype of a Chinese family with atypical Reis-Bückler corneal dystrophy (RBCD). Methods Four patients, two non-carrier relatives of the family were enrolled in the present study. In addition to ophthalmologic examinations, PCR amplification and DNA sequencing of exons 4, 11, 12, and 14 of the TGFBI gene were carried out. Exon 14 was also sequenced in 100 healthy controls. Results A G to A transition at eodon 623 in all affected members was identified. This mutation resulted in a substitution of glyeine (GGC) to aspartic acid (GAC) at the protein level. None of the healthy family members, or any of the 100 control subjects carried this mutation. Conclusion The G623D mutation of the TGFBI gene caused an atypical Reis-Buckler corneal dystrophy in this family. This mutation is reported in Chinese for the first time.     

老年糖尿病患者下肢血管病变25例护理分析

糖尿病下肢血管病变是糖尿病的并发症之一,是导致下肢截肢,特别是高位截肢的主要原因[1],若能得到积极治疗和护理可使病情好转,并可提高糖尿病患者的生活质量和存活时间,现将我科2008年1月～2009年12月对25例糖尿病合并下肢血管病变患者进行的预防治疗和护理体会总结如下.