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91.
Rice body formation is generally a rare disorder related to rheumatoid arthritis. It can also be observed in cases of systemic
lupus erythematosus, seronegative arthritis, infectious arthritis (tuberculosis, atypical mycobacterial infection), nonspecific
arthritis, and osteoarthritis. It is generally located within joints or bursae. Multiple rice bodies of tendon sheaths are
rarely encountered. Rice body formation may also be encountered without underlying systemic disorders. We present a case of
multiple rice body formation that accompanied chronic nonspecific tenosynovitis of the flexor tendons of the wrist. 相似文献
92.
G. Mumcu H. Sur N. Inanc U. Karacayli H. Cimilli N. Sisman T. Ergun H. Direskeneli 《Journal of oral pathology & medicine》2009,38(10):785-791
Background: Although number, frequency and healing time of oral ulcers and pain are generally used for clinical practice and studies in Behcet's disease (BD) and recurrent aphthous stomatitis (RAS), no standardized activity index is currently present to monitor clinical manifestations associated with oral ulcers. The aim of this study was to develop a standardized composite index (CI) to assess oral ulcer activity in BD and RAS.
Methods: In this cross-sectional study, 121 patients with BD and 45 patients with RAS were included. Sixty-five percentage of BD and 68.9% of RAS patients were in active stage during the previous 3 months. The developed CI included the presence of oral ulcers, ulcer-related pain and functional status and was evaluated in patients with both active and inactive disease for content validity.
Results: Composite index score was observed to be higher in active patients with RAS (6.94 ± 2.19) compared with active BD patients (6.01 ± 2.04) ( P = 0.04). The number of oral ulcers and healing time of oral ulcers were significantly higher in RAS compared with BD ( P = 0.018, P = 0.001 respectively). CI score correlated with the number of oral ulcers in both BD and RAS ( P = 0.000, P = 0.002 respectively). CI score was '0' for inactive patients without oral ulcer in BD and RAS.
Conclusions: The presented CI as an oral ulcer activity index seems to be a reliable and suitable tool for evaluating the clinical impact and disease-specific problems in BD and RAS. 相似文献
Methods: In this cross-sectional study, 121 patients with BD and 45 patients with RAS were included. Sixty-five percentage of BD and 68.9% of RAS patients were in active stage during the previous 3 months. The developed CI included the presence of oral ulcers, ulcer-related pain and functional status and was evaluated in patients with both active and inactive disease for content validity.
Results: Composite index score was observed to be higher in active patients with RAS (6.94 ± 2.19) compared with active BD patients (6.01 ± 2.04) ( P = 0.04). The number of oral ulcers and healing time of oral ulcers were significantly higher in RAS compared with BD ( P = 0.018, P = 0.001 respectively). CI score correlated with the number of oral ulcers in both BD and RAS ( P = 0.000, P = 0.002 respectively). CI score was '0' for inactive patients without oral ulcer in BD and RAS.
Conclusions: The presented CI as an oral ulcer activity index seems to be a reliable and suitable tool for evaluating the clinical impact and disease-specific problems in BD and RAS. 相似文献
93.
Osman Faruk Senyuz Nur Danismend Ergun Erdogan Daver Yeker Cenk Buyukunal Nafi Oruc 《Surgery today》1989,19(6):764-767
Five infants with congenital lobar emphysema whose main symptoms included dyspnea, cyanosis and recurrent respiratory infections,
are presented herein. The most reliable diagnostic tool was plain chest X-ray films with antero-posterior and lateral views,
while radio-isotopic investigation of the lung perfusion state took second place in the diagnosis of this disease. The affected
lobes were the left upper lobe in four patients and the right middle lobe in one. Lobectomy was performed with good results
in 4 patients, however, 1 infant was lost following an emergency thoracotomy. 相似文献
94.
Effect of a dilacerated root on stress distribution to the tooth and supporting tissues 总被引:3,自引:0,他引:3
D.D.S. M.S. Ph.D.Emine Celik D.D.S. M.S. Ph.D.Ergun Aydinlik 《The Journal of prosthetic dentistry》1991,65(6):771-777
The configuration of the root of a prospective abutment tooth has a significant influence on its potential load-bearing capacity. Dilaceration is an angulation in the root or crown. This abnormality may also affect the stability and longevity of an abutment. Finite element stress analysis was used to investigate the effect of a root dilaceration on stress distribution to the tooth and its supporting structures. A normal and a dilacerated single-rooted tooth under three loads (axial, distooblique, and mesio-oblique) were analyzed and compared. The results indicated that a dilaceration concentrates the stresses in the supporting structures and may be taken into consideration as a risk factor in abutment selection. 相似文献
95.
Tulin Budak-Alpdogan Onder Alpdogan Debabrata Banerjee Eunice Wang Malcolm A S Moore Joseph R Bertino 《Molecular therapy》2004,10(3):574-584
An SFG-based retroviral bicistronic vector containing a double-mutant dihydrofolate reductase-cytidine deaminase fusion cDNA (F/S DHFR-CD) with IRES-eGFP confers resistance to both methotrexate (MTX) and cytarabine (ara-C). Two weeks after transplantation with marrow transduced with either a fusion or a control gene (eGFP-IRES-NeoR), human lymphoma (SKI-DLCL-1) cells were injected sc into the flanks of nonobese diabetic/severe combined immune deficiency mice. In mock-transplanted mice, maximal tolerated dose (MTD) of posttransplant MTX/ara-C (15/10 mg/kg/day, x3) was unable to control tumor growth. Transfer of the fusion gene allowed doses of MTX/ara-C (25/15 mg/kg/day, x4) twofold higher than the MTD to be tolerated. The tumor burden defined the efficiency of posttransplant chemotherapy; early treatment, 48 h after tumor inoculation, provided tumor-free survival, while starting treatment after having palpable tumor growth (7 days) delayed tumor growth a median time of 28 days. In addition, the early treated group had higher gene expression in peripheral blood and marrow cells than the late treated group (P < 0.05), suggesting that early treatment allowed for enrichment of transduced marrow progenitors. These results encourage clinical studies using this retroviral fusion gene construct. 相似文献
96.
Cakir E Deniz O Ozcan O Tozkoparan E Yaman H Akgul EO Bilgi C Bilgic H Ekiz K Erbil MK 《Clinical biochemistry》2005,38(3):234-238
BACKGROUND: Diagnosis of tuberculous pleuritis is difficult because of its nonspecific clinical presentation and decreased efficiency of traditional diagnostic methods. We investigated the use of procalcitonin (PCT) concentration in tuberculous pleuritis diagnosis. METHODS: A prospective clinical study was performed with two different patient groups. A total of 28 patients were included: 18 with tuberculosis and 10 with nontuberculous pleurisy. Serum and pleural fluid PCT concentrations were evaluated before treatment. RESULTS: Serum and pleural fluid PCT concentrations were statistically different between tuberculous and nontuberculous pleurisy groups (P = 0.012 and P = 0.004, respectively), even though they were not elevated in relation to the cut-off level of 0.5 ng/mL. A positive and significant correlation was detected between serum and pleural fluid PCT levels (r = 0.49, P = 0.008). Diagnostic specificity and sensitivity values for serum and pleural fluid PCT in discriminating tuberculous from nontuberculous pleurisy were 80% and 72.2%, and 90% and 66.7% at the 0.081 and 0.113 ng/mL cut-off values, respectively. CONCLUSION: Relative to the current cut-off level of 0.5 ng/mL, PCT concentration is not a useful parameter for the diagnosis of tuberculous pleurisy. Because there were PCT levels in patients with tuberculous pleurisy that were below the current cut-off level but were significantly different from those of the nontuberculous group, the use of PCT should be further investigated. 相似文献
97.
98.
Ufuk Ates Ergun Ergun Gulnur Gollu Sumeyye Sozduyar Meltem Kologlu Murat Cakmak Huseyin Dindar Aydin Yagmurlu 《Journal of pediatric surgery》2018,53(3):452-455
Introduction
Pilonidal sinus (PS) is an infectious and inflammatory disease of sacrococcygeal region. Current methods include; surgical excision with/without suturing the defect, rhomboid excision and flap and chemical substance application. In this study, crystallized phenol application was compared to excision and primary closure.Patients and methods
This retrospective study included pediatric patients with PS who were treated with excision and primer closure technique and phenol application. The patients' medical data were analyzed retrospectively.Results
This study included 117 patients with PS. There were 52 girls (44%) and 65 boys (56%). Mean age of children was 15.6 (12–20) years. Excision and primary closure were applied to 77 patients (66%) and phenol was applied to 40 patients (34%). The children in phenol group were discharged on the operation day; mean hospitalization time in the excision and primary closure group was 2.7 (1–14) days. Mean follow up was 44.6 (8–82) months for primary excision and closure group and 8.1 (1–19) months for phenol group.Conclusion
Although many surgical and non-surgical treatment modalities have been described for PS, the optimal one remains unknown. Limited with the retrospective nature of the data, crystallized phenol application seems a feasible minimal invasive alternative to primary closure of PS with lower recurrence and complication rates in children.Treatment study
Level III 相似文献99.
Orhan Yilmaz Gulin Sunter Celal Salcini P?nar Kahraman Koytak Tulin Tanridag Onder Us Kayihan Uluc 《JOURNAL OF CLINICAL NEUROLOGY》2016,12(2):166-171
MethodsThe study investigated 60 hands of 35 patients with clinical CTS and 60 hands of 34 healthy controls. Routine median and ulnar nerve conduction studies and MUNE analysis according to the multipoint stimulation method were performed.ResultsThe most common electrophysiological abnormality was reduced conduction velocity in the median sensory nerve (100% of the hands). The MUNE value was significantly lower for the patient group than for the control group (p=0.0001). ROC analysis showed that a MUNE value of 121 was the optimal cutoff for differentiating between patients and controls, with a sensitivity of 63.3% and a specificity of 68.3%. MUNE values were lower in patients with complaints of numbness, pain, and weakness in the median nerve territory (p<0.05, for all comparisons), and lower in patients with hypoesthesia than in patients with normal neurological findings (p=0.023).ConclusionsThe MUNE technique is sensitive in detecting motor nerve involvement in CTS patients who present with sensorial findings, and it may be useful in detecting the loss of motor units during the early stages of CTS. Larger-scale prospective clinical trials assessing the effect of early intervention on the outcome of these patients would help in confirming the possible benefit of detecting subclinical motor-unit loss in CTS. 相似文献