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41.
Background - A case of primary thyroid T cell lymphoma leading to lethal tracheal perforation during chemotherapy is described. 相似文献
42.
An early radiological sign of anterior cruciate ligament deficiency is described. A retrospective study of the radiographs of 38 patients with chronic anterior cruciate ligament deficiency was performed. In 36 patients from this group an osteophyte was present on the medial femoral condyle adjacent to the medial tibial spine. This was best seen on a 30 ° notch view and was the earliest radiographic sign of chronic anterior cruciate ligament deficiency. 相似文献
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Michael Bach Graham E. Holder 《Documenta ophthalmologica. Advances in ophthalmology》1996,92(3):193-202
The pattern electroretinogram was recorded to checkerboard stimuli with a wide range of check sizes and two stimulus field
sizes. Check sizes ranged from 0.25° to 7° (field size, 16°×14°) and 0.25° to 15° (field size, 32°×27°) in 14 and seven subjects,
respectively. Reversal rate was 4.5/s. For minimal intrusion of blink artifacts the interrupted stimulation technique was
employed. The P50 and N95 components of the pattern electroretinogram were evaluated separately. With both stimulus field
sizes amplitude of P50 and N95 was maximal between 0.75° and 1°. With smaller check sizes the amplitude dropped monotonically.
With larger check sizes field size played a role: with the 16°×14° field, P50 gradually dropped to 89% from 1° to 7°, which
was paralleled by N95 only up to 7°, where N95 dropped to 81% (p<0.05). With the 32°×27° field, there was no significant difference in size dependency between P50 and N95 for large checks,
both components staying constant from 1° to 15° We conclude that there is only minor large-check attenuation of the pattern
electroretinogram, especially with a large field. The apparent field-size dependency may explain previous discrepancies in
the literature. 相似文献
46.
GABA RECEPTORS: AS COMPLEX AS ABC? 总被引:1,自引:0,他引:1
Graham A. R. Johnston 《Clinical and experimental pharmacology & physiology》1994,21(7):521-526
47.
Brenda M Sandmaier Storb Rainer Yanfang Liu Erlinda B Santos Eileen Bryant Friedrich G Schuening H Joachim Deeg Kristy Seidel Theodore Graham 《Transplant immunology》1996,4(4):271-274
920 cGy total body irradiation (TBI) is adequate for consistently successful engraftment of marrow from dog leukocyte antigen (DLA)-identical littermates; however, the dose is inadequate to ensure a marrow graft from DLA-nonidentical unrelated donors. Such mismatched grafts are successful only after 1800 cGy, given in three fractions. While anti-T-cell reagents enhance engraftment of DLA-identical littermate marrow after 920 cGy, they fail to be effective in the DLA-nonidentical setting. However, a monoclonal antibody (mAb) to CD44, S5, was found to be very effective in enhancing engraftment of DLA-nonidentical marrow. The current study asked whether mAb S5 was also effective in the setting of DLA-identical littermate transplants. To this purpose, the TBI dose was lowered to 450 cGy, a dose after which 70% of such grafts failed. Four dogs were treated with antibody S5, 0.2 mg/kg on days −7 though −2 (per previously published protocol), given 450 cGy TBI followed by marrow grafts from their DLA-identical littermates. All four dogs rejected their grafts; two of these died from marrow aplasia, and two survived with endogenous marrow recovery. This result was not statistically significantly different from that in 17, historical (n = 5) and concurrent (n = 12), control dogs where 11 of 17 animals rejected. Even if ten experimental animals were transplanted and all six remaining dogs engrafted, the results still would not have been significantly different from control. This result is in contrast to the successful engraftment promoted by pretreatment with antibody S5 of DLA-nonidentical unrelated dogs, consistent with the notion that different host cells are involved in graft rejection in the two disparate histocompatibility settings. 相似文献
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